PANTHER Gene Information

Gene Symbol(s):

Organism:

lepisosteus oculatus

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Gene Name:

dihydrofolate reductase

Gene ID:

ENSLOCG00000015270.1

Protein ID:

W5NDT1

Persistent Id:

PTN002735706

Alternate Ids:

W5NDT1_LEPOC(UniProtKB-ID)	ENSLOCP00000018790(Ensembl_PRO)
573890906(GI)	XM_006633150(refSeq)
AHAT01025403(EMBL)	ENSLOCG00000015270(Ensembl)
ENSLOCT00000018822(Ensembl_TRS)	W5NDT1(Synonym)
102694946(GeneID)
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PANTHER Classification

PANTHER Family:	DIHYDROFOLATE REDUCTASE (PTHR48069)
PANTHER Subfamily:	DIHYDROFOLATE REDUCTASE (PTHR48069:SF5)
PANTHER GO-slim Molecular Function:	nucleotide binding oxidoreductase activity
PANTHER GO-slim Biological Process:	dicarboxylic acid metabolic process amide metabolic process organonitrogen compound biosynthetic process organic cyclic compound biosynthetic process cellular nitrogen compound biosynthetic process aromatic compound biosynthetic process heterocycle biosynthetic process folic acid-containing compound metabolic process
PANTHER GO-slim Cellular Component:	mitochondrion
PANTHER protein class:	reductase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	NADP binding, dihydrofolate reductase activity
GO BP Complete:	dihydrofolate metabolic process, folic acid metabolic process, tetrahydrofolate biosynthetic process, one-carbon metabolic process
GO CC Complete:	mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
XENLA\|Gene=dhfrl.S\|UniProtKB=A0A8J1MSA8	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-975267\|UniProtKB=Q28J42	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000016391.2\|UniProtKB=H2MP65	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-060929-1190\|UniProtKB=Q1LWC6	Danio rerio	LDO
CIOIN\|Ensembl=ENSCING00000019832.1\|UniProtKB=H2XNW6	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000022228.1\|UniProtKB=H2XLB1	Ciona intestinalis	O
BRAFL\|Gene=LOC118412318\|UniProtKB=A0A9J7KUU4	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC575335\|UniProtKB=A0A7M7RBU0	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00007974\|UniProtKB=Q93341	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00033316\|UniProtKB=A8XF85	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00099425\|UniProtKB=A0A2A6C9P0	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00110364\|UniProtKB=A0A2A6D2B5	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00274181\|UniProtKB=A0A2A6BKN1	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0004087\|UniProtKB=P17719	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP010278\|UniProtKB=Q7Q0L5	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC030679\|UniProtKB=D6WRE9	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_240087\|UniProtKB=E9GAU4	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_301858\|UniProtKB=E9GAU3	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG98642\|UniProtKB=T1G9P0	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g210271\|UniProtKB=A7SCT0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g146670\|UniProtKB=A7T5F9	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG52382\|UniProtKB=B3RI81	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_29079\|UniProtKB=A9VA22	Monosiga brevicollis	O
YEAST\|SGD=S000005762\|UniProtKB=P07807	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ACR124W\|UniProtKB=Q75BZ5	Eremothecium gossypii	O
CANAL\|CGD=CAL0000177250\|UniProtKB=Q5A5E0	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_C12771g\|UniProtKB=Q6CC38	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_06108\|UniProtKB=Q5B022	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_2G08890\|UniProtKB=Q4X1T0	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU16651\|UniProtKB=U9W889	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_08803\|UniProtKB=A7ETZ6	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_13852\|UniProtKB=Q0U312	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPCC1223.08c\|UniProtKB=P36591	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_01198\|UniProtKB=B6K009	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNJ01940\|UniProtKB=Q07801	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_10394\|UniProtKB=A0A0D1CPU1	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_11433\|UniProtKB=E3KLR5	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_91777\|UniProtKB=F4PBG6	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0286755\|UniProtKB=Q54LA0	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_88906\|UniProtKB=F0ZSE1	Dictyostelium purpureum	O
THAPS\|EnsemblGenome=THAPSDRAFT_261857\|UniProtKB=B8BYC4	Thalassiosira pseudonana	O
MAIZE\|EnsemblGenome=Zm00001eb027080\|UniProtKB=A0A804LPV2	Zea mays	O
HELAN\|EnsemblGenome=HanXRQr2_Chr15g0709291\|UniProtKB=A0A251SBZ0	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C500271850\|UniProtKB=A0A9R1X9X5	Lactuca sativa	O
GOSHI\|Gene=LOC107960692\|UniProtKB=A0A1U8PQF3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107905452\|UniProtKB=A0A1U8JFU3	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_034096\|UniProtKB=A0A061FK09	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g024737mg\|UniProtKB=A0A067HA24	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_005G230700v3\|UniProtKB=A0A2K2AL36	Populus trichocarpa	O
POPTR\|Gene_ORFName=POPTR_005G230400\|UniProtKB=A0A3N7GB50	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_18G020100\|UniProtKB=A0A2C9TZL9	Manihot esculenta	O
MYCTU\|Gene_OrderedLocusName=Rv2763c\|UniProtKB=P9WNX1	Mycobacterium tuberculosis	O
MYCGE\|EnsemblGenome=MG_228\|UniProtKB=P47470	mycoplasma genitalium	O
STRR6\|EnsemblGenome=spr1429\|UniProtKB=Q7CRB0	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_01434\|UniProtKB=Q2FYK6	Staphylococcus aureus	O
LISMO\|Gene=Q8Y627_LISMO\|UniProtKB=Q8Y627	Listeria monocytogenes	O
THEMA\|EnsemblGenome=TM_1641\|UniProtKB=Q60034	Thermotoga maritima	O
DEIRA\|EnsemblGenome=DR_2632\|UniProtKB=Q9RR65	Deinococcus radiodurans	O
GLOVI\|Gene=Q7NHQ9_GLOVI\|UniProtKB=Q7NHQ9	Gloeobacter violaceus	O
BACTN\|EnsemblGenome=BT_2048\|UniProtKB=Q8A638	Bacteroides thetaiotaomicron	O
CHLTR\|EnsemblGenome=CT_612\|UniProtKB=O84618	Chlamydia trachomatis	O
RHOBA\|EnsemblGenome=RB12617\|UniProtKB=Q7UIC9	Rhodopirellula baltica	O
FUSNN\|EnsemblGenome=FN0241\|UniProtKB=Q8RGP5	Fusobacterium nucleatum	O
NEIMB\|EnsemblGenome=NMB0308\|UniProtKB=Q9K168	Neisseria meningitidis serogroup b	O
GEOSL\|EnsemblGenome=GSU0571\|UniProtKB=Q74FN5	Geobacter sulfurreducens	O
BRADU\|Gene=folA\|UniProtKB=Q89G37	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_1993\|UniProtKB=Q83AB2	Coxiella burnetii	O
HAEIN\|EnsemblGenome=HI_0899\|UniProtKB=P43791	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_3646\|UniProtKB=Q8EB86	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_0440\|UniProtKB=Q9KUS5	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC0788\|UniProtKB=Q8PCE6	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA0350\|UniProtKB=Q9I6E3	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM0087\|UniProtKB=Q8ZRW1	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO0486\|UniProtKB=A0A3N4BLI0	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAB96616\|UniProtKB=P0ABQ4	Escherichia coli	O