PANTHER Gene Information   
Gene Symbol(s): RYR2
Organism: Macaca mulatta
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Gene Name: Ryanodine receptor 2
Gene ID: ENSMMUG00000001060.4
Protein ID: F6QN38
Persistent Id: PTN000346522
Alternate Ids:
F6QN38_MACMU(UniProtKB-ID) ENSMMUT00000001510(Ensembl_TRS)
966924023(GI) XM_015126668(refSeq)
ENSMMUG00000001060(Ensembl) 717179(GeneID)
F6QN38(Synonym) ENSMMUP00000001421(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: B30.2/SPRY DOMAIN-CONTAINING PROTEIN (PTHR46399)
PANTHER Subfamily: RYANODINE RECEPTOR 2 (PTHR46399:SF7)  
PANTHER GO-slim Molecular Function: calcium channel activity
ligand-gated monoatomic cation channel activity
PANTHER GO-slim Biological Process: release of sequestered calcium ion into cytosol
striated muscle contraction
PANTHER GO-slim Cellular Component: bounding membrane of organelle
calcium channel complex
endoplasmic reticulum membrane
Z disc
sarcoplasmic reticulum
sarcolemma
PANTHER protein class:
Pathway Categories: Beta1 adrenergic receptor signaling pathway
   ER-type Ca2+ channel
CCKR signaling map
   RYR1/2/3
Beta2 adrenergic receptor signaling pathway
   ER-type Ca2+ channel

GO MF Complete: protein kinase binding, intracellularly gated calcium channel activity, identical protein binding, suramin binding, calcium channel activity, ryanodine-sensitive calcium-release channel activity, calmodulin binding, organic cyclic compound binding, calcium-induced calcium release activity, calcium ion binding, protein kinase A regulatory subunit binding, protein kinase A catalytic subunit binding, enzyme binding
GO BP Complete: positive regulation of heart rate, type B pancreatic cell apoptotic process, striated muscle contraction, cardiac muscle contraction, calcium ion transport into cytosol, response to hypoxia, cellular response to epinephrine stimulus, regulation of atrial cardiac muscle cell action potential, positive regulation of sequestering of calcium ion, calcium ion transport, calcium ion transmembrane transport, positive regulation of the force of heart contraction, regulation of ventricular cardiac muscle cell action potential, release of sequestered calcium ion into cytosol, establishment of localization in cell, cellular response to caffeine, calcium-mediated signaling, response to muscle stretch, response to muscle activity, transmembrane transport, Purkinje myocyte to ventricular cardiac muscle cell signaling, ventricular cardiac muscle cell action potential, embryonic heart tube morphogenesis, left ventricular cardiac muscle tissue morphogenesis, cardiac muscle hypertrophy, intracellular calcium ion homeostasis, regulation of heart rate, detection of calcium ion, response to redox state, calcium ion transmembrane import into cytosol, release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, response to caffeine, establishment of protein localization to endoplasmic reticulum, regulation of cardiac muscle contraction by calcium ion signaling, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of cardiac muscle contraction, regulation of SA node cell action potential, regulation of AV node cell action potential
GO CC Complete: Z disc, calcium channel complex, sarcoplasmic reticulum, smooth endoplasmic reticulum, sarcolemma, membrane, protein-containing complex, sarcomere, sarcoplasmic reticulum membrane
Reactome Pathways: -