PANTHER Gene Information

Gene Symbol(s):

TRIM5

Organism:

Macaca mulatta

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Gene Name:

Tripartite motif-containing protein 5

Gene ID:

TRIM5

Protein ID:

Q0PF16

Persistent Id:

PTN008394641

Alternate Ids:

124053417(GI)	TRIM5(Symbol)
Q2YEN1(AltAccession)	TRIM5_MACMU(UniProtKB-ID)
TRIM5(Synonym)	574288(GeneID)
ABG67966(EMBL-CDS)	AY899883(EMBL)
2.3.2.27(EC)	NM_001032910(refSeq)
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PANTHER Classification

PANTHER Family:	E3 UBIQUITIN-PROTEIN LIGASE TRIM (PTHR24103)
PANTHER Subfamily:	TRIPARTITE MOTIF-CONTAINING PROTEIN 5 (PTHR24103:SF416)
PANTHER GO-slim Molecular Function:	ubiquitin protein ligase activity
PANTHER GO-slim Biological Process:	protein ubiquitination innate immune response regulation of gene expression
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	ubiquitin-protein ligase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	cyclosporin A binding, ubiquitin-protein transferase activity, protein kinase binding, peptidyl-prolyl cis-trans isomerase activity, zinc ion binding, identical protein binding, ubiquitin protein ligase activity, protein binding, protein homodimerization activity, pattern recognition receptor activity, metal ion binding, transferase activity
GO BP Complete:	regulation of protein localization, positive regulation of canonical NF-kappaB signal transduction, positive regulation of MAPK cascade, protein folding, positive regulation of DNA-binding transcription factor activity, positive regulation of NF-kappaB transcription factor activity, regulation of viral entry into host cell, activation of innate immune response, suppression of viral release by host, negative regulation of viral entry into host cell, autophagy, innate immune response, apoptotic process, regulation of gene expression, defense response to virus, protein K63-linked ubiquitination, negative regulation of viral genome replication, regulation of lipopolysaccharide-mediated signaling pathway, protein ubiquitination, negative regulation of viral transcription
GO CC Complete:	nucleus, cytoplasm, P-body, extracellular region

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=16276\|UniProtKB=Q9C035	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000003258\|UniProtKB=Q5D7J1	Pan troglodytes	LDO
GORGO\|Gene=TRIM5\|UniProtKB=Q5C8T6	Gorilla gorilla gorilla	LDO
GORGO\|Ensembl=ENSGGOG00000014804.3\|UniProtKB=G3S2X6	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=3035181\|UniProtKB=E9PWL0	Mus musculus	O
MOUSE\|MGI=MGI=98178\|UniProtKB=P15533	Mus musculus	O
MOUSE\|MGI=MGI=4821257\|UniProtKB=D3YVI9	Mus musculus	O
RAT\|RGD=1566132\|UniProtKB=A0A0G2JYE1	Rattus norvegicus	O
MOUSE\|MGI=MGI=3646853\|UniProtKB=E9PV98	Mus musculus	O
MOUSE\|MGI=MGI=1923931\|UniProtKB=Q99PQ1	Mus musculus	O
MOUSE\|MGI=MGI=4821183\|UniProtKB=D3Z3L3	Mus musculus	LDO
RAT\|RGD=1304579\|UniProtKB=A0A0G2K6C7	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000038536.3\|UniProtKB=A0A3Q1MQM2	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000005609.6\|UniProtKB=G5E5Y3	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000052606.1\|UniProtKB=A0A3Q1LM24	Bos taurus	LDO
BOVIN\|Ensembl=ENSBTAG00000005251.6\|UniProtKB=E1BM69	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000014670.6\|UniProtKB=F1RLV7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000055639.1\|UniProtKB=A0A3Q2KXP0	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000054507.1\|UniProtKB=F6TSM5	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000016298.4\|UniProtKB=F7B986	Equus caballus	LDO
HORSE\|Ensembl=ENSECAG00000042725.2\|UniProtKB=A0A3Q2HW62	Equus caballus	O
MONDO\|Ensembl=ENSMODG00000039692.1\|UniProtKB=A0A5F8GSI3	Monodelphis domestica	O
CHICK\|Ensembl=ENSGALG00010029560.1\|UniProtKB=A0A8V1AP69	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000025926.3\|UniProtKB=G1KUV1	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000014928.4\|UniProtKB=H9GLQ3	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000017237.3\|UniProtKB=H9GP47	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000011368.4\|UniProtKB=G1KL65	Anolis carolinensis	O
ORYLA\|Ensembl=ENSORLG00000007167.2\|UniProtKB=H2LSC7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-060825-228\|UniProtKB=F1Q977	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009030.1\|UniProtKB=W5MRJ6	lepisosteus oculatus	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_107250\|UniProtKB=C3ZKR2	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_118421\|UniProtKB=C3ZGA6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417355\|UniProtKB=A0A9J7MTS3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118423726\|UniProtKB=A0A9J7LSV8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417354\|UniProtKB=A0A9J7MU30	Branchiostoma floridae	O
BRAFL\|Gene=LOC118429289\|UniProtKB=A0A9J7M7K9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118426733\|UniProtKB=A0A9J7M0M9	Branchiostoma floridae	O
CAEEL\|WormBase=WBGene00021640\|UniProtKB=Q9N3T6	Caenorhabditis elegans	O
HELRO\|EnsemblGenome=HelroG193539\|UniProtKB=T1FV38	helobdella robusta	O
DICPU\|EnsemblGenome=DICPUDRAFT_96644\|UniProtKB=F0ZA65	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_36_1550\|UniProtKB=Q4Q1S1	Leishmania major	O
PARTE\|EnsemblGenome=GSPATT00006650001\|UniProtKB=A0C977	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019138001\|UniProtKB=A0DPI9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00002189001\|UniProtKB=A0DG93	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00005047001\|UniProtKB=A0BP31	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00004438001\|UniProtKB=A0BCS7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00027177001\|UniProtKB=A0EHR0	Paramecium tetraurelia	O