PANTHER Gene Information

Gene Symbol(s):

Trim5

Organism:

Rattus norvegicus

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Gene Name:

Tripartite motif-containing 5

Gene ID:

1304579

Protein ID:

A0A0G2K6C7

Persistent Id:

PTN007774307

Alternate Ids:

1304579(RGD)	A0A0G2K6C7_RAT(UniProtKB-ID)
ENSRNOP00000073760(Ensembl_PRO)	ENSRNOT00000082645(Ensembl_TRS)
ENSRNOG00000017191(Ensembl)	A0A0G2K6C7(Synonym)
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PANTHER Classification

PANTHER Family:	E3 UBIQUITIN-PROTEIN LIGASE TRIM (PTHR24103)
PANTHER Subfamily:	TRIPARTITE MOTIF-CONTAINING PROTEIN 5 (PTHR24103:SF416)
PANTHER GO-slim Molecular Function:	ubiquitin protein ligase activity
PANTHER GO-slim Biological Process:	protein ubiquitination innate immune response regulation of gene expression
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	ubiquitin-protein ligase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ubiquitin-protein transferase activity, protein kinase binding, zinc ion binding, identical protein binding, ubiquitin protein ligase activity, protein homodimerization activity, transcription coactivator activity, pattern recognition receptor activity, protein-macromolecule adaptor activity
GO BP Complete:	regulation of protein localization, positive regulation of canonical NF-kappaB signal transduction, positive regulation of MAPK cascade, positive regulation of DNA-binding transcription factor activity, positive regulation of NF-kappaB transcription factor activity, regulation of viral entry into host cell, activation of innate immune response, suppression of viral release by host, positive regulation of DNA-templated transcription, negative regulation of viral entry into host cell, autophagy, innate immune response, regulation of gene expression, protein K63-linked ubiquitination, regulation of lipopolysaccharide-mediated signaling pathway
GO CC Complete:	cytoplasm, P-body, omegasome

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=16276\|UniProtKB=Q9C035	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000003258\|UniProtKB=Q5D7J1	Pan troglodytes	LDO
GORGO\|Gene=TRIM5\|UniProtKB=Q5C8T6	Gorilla gorilla gorilla	LDO
GORGO\|Ensembl=ENSGGOG00000014804.3\|UniProtKB=G3S2X6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000335.4\|UniProtKB=A0A1D5QRR8	Macaca mulatta	LDO
MACMU\|Gene=TRIM5\|UniProtKB=Q0PF16	Macaca mulatta	LDO
MOUSE\|MGI=MGI=3646853\|UniProtKB=E9PV98	Mus musculus	O
MOUSE\|MGI=MGI=1923931\|UniProtKB=Q99PQ1	Mus musculus	O
MOUSE\|MGI=MGI=4821183\|UniProtKB=D3Z3L3	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000038536.3\|UniProtKB=A0A3Q1MQM2	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000005609.6\|UniProtKB=G5E5Y3	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000052606.1\|UniProtKB=A0A3Q1LM24	Bos taurus	LDO
BOVIN\|Ensembl=ENSBTAG00000005251.6\|UniProtKB=E1BM69	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000014670.6\|UniProtKB=F1RLV7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000055639.1\|UniProtKB=A0A3Q2KXP0	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000054507.1\|UniProtKB=F6TSM5	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000016298.4\|UniProtKB=F7B986	Equus caballus	LDO
HORSE\|Ensembl=ENSECAG00000042725.2\|UniProtKB=A0A3Q2HW62	Equus caballus	O
MONDO\|Ensembl=ENSMODG00000039692.1\|UniProtKB=A0A5F8GSI3	Monodelphis domestica	O
CHICK\|Ensembl=ENSGALG00010029560.1\|UniProtKB=A0A8V1AP69	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000025926.3\|UniProtKB=G1KUV1	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000014928.4\|UniProtKB=H9GLQ3	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000017237.3\|UniProtKB=H9GP47	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000011368.4\|UniProtKB=G1KL65	Anolis carolinensis	O
ORYLA\|Ensembl=ENSORLG00000007167.2\|UniProtKB=H2LSC7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-060825-228\|UniProtKB=F1Q977	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009030.1\|UniProtKB=W5MRJ6	lepisosteus oculatus	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_107250\|UniProtKB=C3ZKR2	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_118421\|UniProtKB=C3ZGA6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417355\|UniProtKB=A0A9J7MTS3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118423726\|UniProtKB=A0A9J7LSV8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417354\|UniProtKB=A0A9J7MU30	Branchiostoma floridae	O
BRAFL\|Gene=LOC118429289\|UniProtKB=A0A9J7M7K9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118426733\|UniProtKB=A0A9J7M0M9	Branchiostoma floridae	O
CAEEL\|WormBase=WBGene00021640\|UniProtKB=Q9N3T6	Caenorhabditis elegans	O
HELRO\|EnsemblGenome=HelroG193539\|UniProtKB=T1FV38	helobdella robusta	O
DICPU\|EnsemblGenome=DICPUDRAFT_96644\|UniProtKB=F0ZA65	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_36_1550\|UniProtKB=Q4Q1S1	Leishmania major	O
PARTE\|EnsemblGenome=GSPATT00006650001\|UniProtKB=A0C977	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019138001\|UniProtKB=A0DPI9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00002189001\|UniProtKB=A0DG93	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00005047001\|UniProtKB=A0BP31	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00004438001\|UniProtKB=A0BCS7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00027177001\|UniProtKB=A0EHR0	Paramecium tetraurelia	O