PANTHER Gene Information

Gene Symbol(s):

C1R

Organism:

Monodelphis domestica

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Gene Name:

Complement C1r

Gene ID:

ENSMODG00000018171.4

Protein ID:

F7BU27

Persistent Id:

PTN000014207

Alternate Ids:

ENSMODP00000022662(Ensembl_PRO)	XP_007503746(refSeq)
F7BU27(Synonym)	ENSMODT00000023060(Ensembl_TRS)
612052167(GI)	F7BU27_MONDO(UniProtKB-ID)
100016799(GeneID)	ENSMODG00000018171(Ensembl)
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PANTHER Classification

PANTHER Family:	COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED (PTHR24255)
PANTHER Subfamily:	COMPLEMENT C1R SUBCOMPONENT (PTHR24255:SF25)
PANTHER GO-slim Molecular Function:	serine-type endopeptidase activity
PANTHER GO-slim Biological Process:	zymogen activation
PANTHER GO-slim Cellular Component:	extracellular space
PANTHER protein class:	serine protease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	DNA-binding transcription factor activity, metal ion binding, calcium ion binding, serine-type endopeptidase activity, serine-type peptidase activity, sequence-specific DNA binding
GO BP Complete:	complement activation, zymogen activation, complement activation, classical pathway, innate immune response, proteolysis, regulation of DNA-templated transcription
GO CC Complete:	extracellular space, blood microparticle, extracellular region

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=21265\|UniProtKB=Q9NZP8	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000004607.6\|UniProtKB=H2Q5C0	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000011542.3\|UniProtKB=G3R7C3	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000008897.4\|UniProtKB=H9EXP2	Macaca mulatta	O
MOUSE\|MGI=MGI=2660692\|UniProtKB=Q3UZ09	Mus musculus	O
RAT\|RGD=1302936\|UniProtKB=Q6IE64	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000016204.5\|UniProtKB=F1N1S6	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000033913.3\|UniProtKB=F1SLV7	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000014251.4\|UniProtKB=F7A1L2	Equus caballus	O
CANLF\|Ensembl=ENSCAFG00845024953.1\|UniProtKB=A0A8I3S504	Canis lupus familiaris	O
HUMAN\|HGNC=1246\|UniProtKB=P00736	Homo sapiens	LDO
PANTR\|Gene=C1R\|UniProtKB=Q5R1W3	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000004606.7\|UniProtKB=H2RB01	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000039052.1\|UniProtKB=A0A2I2ZAV7	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000006470.4\|UniProtKB=H9FZ50	Macaca mulatta	LDO
MOUSE\|MGI=MGI=3779804\|UniProtKB=Q8CFG9	Mus musculus	O
MOUSE\|MGI=MGI=1355313\|UniProtKB=Q8CG16	Mus musculus	LDO
RAT\|RGD=1309091\|UniProtKB=B5DEH7	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000008612.5\|UniProtKB=A5D9E9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000060530.1\|UniProtKB=A0A480RJC3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000021429.4\|UniProtKB=A0A9L0SLY6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000045616.2\|UniProtKB=A0A337SDE6	Felis catus	O
FELCA\|Ensembl=ENSFCAG00000000177.6\|UniProtKB=M3VU82	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845025120.1\|UniProtKB=A0A8I3PJQ7	Canis lupus familiaris	LDO
CHICK\|Ensembl=ENSGALG00010023655.1\|UniProtKB=A0A8V0ZNL2	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000007262.4\|UniProtKB=H9GCQ9	Anolis carolinensis	LDO
XENLA\|Gene=c1r.L\|UniProtKB=Q6GLK4	Xenopus laevis	O
XENTR\|Gene=LOC116406517\|UniProtKB=A0A8J1JZ09	Xenopus tropicalis	O
XENLA\|Gene=MGC130869.L\|UniProtKB=Q2VPN1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-995376\|UniProtKB=A0A8J0QSW6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000012367.2\|UniProtKB=H2MAD0	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000007599.1\|UniProtKB=W5MLG1	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000007589.1\|UniProtKB=W5MLE9	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000007609.1\|UniProtKB=W5MLI1	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000012352.2\|UniProtKB=H2MAB2	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000007540.1\|UniProtKB=W5MLB6	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000002726.3\|UniProtKB=F6TQ36	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000002747.3\|UniProtKB=F7AGV3	Ciona intestinalis	O
BRAFL\|Gene=LOC118430323\|UniProtKB=A0A9J7MBI6	Branchiostoma floridae	O
STRPU\|EnsemblGenome=GeneID_585663\|UniProtKB=A0A7M7P290	Strongylocentrotus purpuratus	O
ANOGA\|EnsemblGenome=AGAP029047\|UniProtKB=A0A1Y9IGS6	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003136\|UniProtKB=D6WF18	Tribolium castaneum	O
IXOSC\|EnsemblGenome=ISCW007056\|UniProtKB=B7PTI3	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW007148\|UniProtKB=B7PVI9	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g215748\|UniProtKB=A7SQB2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g223268\|UniProtKB=A7T766	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g138799\|UniProtKB=A7SZ55	Nematostella vectensis	O