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Gene Symbol(s):
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Trim21
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| Organism: |
Mus musculus |
| View Gene in Tree |
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| Gene Name: |
E3 ubiquitin-protein ligase TRIM21
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| Gene ID: |
MGI:106657
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| Protein ID: |
Q62191
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| Persistent Id: |
PTN000646688 |
| Alternate Ids: |
| RO52_MOUSE(UniProtKB-ID) |
Ssa1(Synonym) |
| 507042968(GI) |
2.3.2.27 {ECO:0000269|PubMed:17579016}(EC) |
| L27990(EMBL) |
MGI:106657(MGI) |
| Trim21(Symbol) |
AAB51154(EMBL-CDS) |
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Show All
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| Pathway Categories: |
No pathway information available
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| GO MF Complete: |
DNA binding, ubiquitin-protein transferase activity, zinc ion binding, identical protein binding, ubiquitin protein ligase activity, RNA binding, protein binding, transcription coactivator activity
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| GO BP Complete: |
positive regulation of protein binding, positive regulation of cell cycle, positive regulation of DNA-binding transcription factor activity, protein K27-linked ubiquitination, negative regulation of innate immune response, stress granule disassembly, pyroptotic inflammatory response, proteasomal protein catabolic process, protein autoubiquitination, protein K48-linked ubiquitination, negative regulation of NF-kappaB transcription factor activity, protein polyubiquitination, response to type II interferon, negative regulation of protein deubiquitination, protein monoubiquitination, protein destabilization, positive regulation of autophagy, regulation of viral entry into host cell, suppression of viral release by host, innate immune response, regulation of gene expression, protein K63-linked ubiquitination, protein K6-linked ubiquitination, protein ubiquitination, negative regulation of viral transcription
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| GO CC Complete: |
nucleus, cytoplasmic stress granule, cytoplasm, P-body, cytoplasmic vesicle, SCF ubiquitin ligase complex, ribonucleoprotein complex, autophagosome, nucleoplasm
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| Reactome Pathways: |
Cellular responses to stimuli, Immune System, Innate Immune System, Regulation of innate immune responses to cytosolic DNA, Cellular response to chemical stress, KEAP1-NFE2L2 pathway, Antigen processing: Ubiquitination & Proteasome degradation, Class I MHC mediated antigen processing & presentation, Cytosolic sensors of pathogen-associated DNA , Adaptive Immune System, Cellular responses to stress
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