PANTHER Gene Information   
Gene Symbol(s): Trim21
Organism: Rattus norvegicus
View Gene in Tree
Tree Reduced Tree  
Tree Reduced Tree
Gene Name: RING-type E3 ubiquitin transferase
Gene ID: 1305795
Protein ID: D4ACF2
Persistent Id: PTN000646689
Alternate Ids:
D4ACF2(Synonym) NM_001082572(refSeq)
ENSRNOT00000024992(Ensembl_TRS) D4ACF2_RAT(UniProtKB-ID)
ENSRNOP00000024992(Ensembl_PRO) 1305795(RGD)
ENSRNOG00000018517(Ensembl) 564330089(GI)
308901(GeneID)
Show All

PANTHER Classification
PANTHER Family: E3 UBIQUITIN-PROTEIN LIGASE TRIM (PTHR24103)
PANTHER Subfamily: E3 UBIQUITIN-PROTEIN LIGASE TRIM21 (PTHR24103:SF46)  
PANTHER GO-slim Molecular Function: ubiquitin protein ligase activity
PANTHER GO-slim Biological Process: protein ubiquitination
innate immune response
regulation of gene expression
PANTHER GO-slim Cellular Component: cytoplasm
PANTHER protein class: ubiquitin-protein ligase
Pathway Categories: No pathway information available
GO MF Complete: ubiquitin-protein transferase activity, zinc ion binding, identical protein binding, ubiquitin protein ligase activity, transcription coactivator activity
GO BP Complete: positive regulation of cell cycle, positive regulation of DNA-binding transcription factor activity, protein K27-linked ubiquitination, negative regulation of innate immune response, stress granule disassembly, positive regulation of DNA-templated transcription, pyroptotic inflammatory response, proteasomal protein catabolic process, protein autoubiquitination, protein K48-linked ubiquitination, negative regulation of NF-kappaB transcription factor activity, protein polyubiquitination, response to type II interferon, negative regulation of protein deubiquitination, protein monoubiquitination, protein destabilization, positive regulation of autophagy, regulation of viral entry into host cell, suppression of viral release by host, innate immune response, regulation of gene expression, protein K63-linked ubiquitination, protein K6-linked ubiquitination, protein ubiquitination, negative regulation of viral transcription
GO CC Complete: nucleus, cytoplasmic stress granule, cytoplasm, SCF ubiquitin ligase complex, nucleoplasm
Reactome Pathways: Cellular response to chemical stress, Cellular responses to stress, Class I MHC mediated antigen processing & presentation, Immune System, Antigen processing: Ubiquitination & Proteasome degradation, Cellular responses to stimuli, Innate Immune System, KEAP1-NFE2L2 pathway, Regulation of innate immune responses to cytosolic DNA, Adaptive Immune System, Cytosolic sensors of pathogen-associated DNA