PANTHER Gene Information

Gene Symbol(s):

Slc24a5

Organism:

Mus musculus

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Gene Name:

Sodium_potassium_calcium exchanger 5

Gene ID:

MGI:2677271

Protein ID:

Q8C261

Persistent Id:

PTN000091000

Alternate Ids:

Solute carrier family 24 member 5(Synonym)	AY236527(EMBL)
ENSMUSG00000035183(Ensembl)	AAH94232(EMBL-CDS)
NCKX5_MOUSE(UniProtKB-ID)	81876138(GI)
Slc24a5(Symbol)	MGI:2677271(MGI)
NM_175034(refSeq)	ENSMUST00000070353(Ensembl_TRS)
317750(GeneID)	Q8CJF1(AltAccession)
ENSMUSP00000063887(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	SODIUM/POTASSIUM/CALCIUM EXCHANGER (PTHR10846)
PANTHER Subfamily:	SODIUM_POTASSIUM_CALCIUM EXCHANGER 5 (PTHR10846:SF61)
PANTHER GO-slim Molecular Function:	sodium ion transmembrane transporter activity potassium ion transmembrane transporter activity calcium channel activity active monoatomic ion transmembrane transporter activity antiporter activity
PANTHER GO-slim Biological Process:	calcium ion transmembrane transport intracellular calcium ion homeostasis
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	secondary carrier transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	calcium channel activity, calcium, potassium:sodium antiporter activity, calcium ion transmembrane transporter activity, symporter activity
GO BP Complete:	melanin biosynthetic process, negative regulation of melanin biosynthetic process, calcium ion import, potassium ion transmembrane transport, monoatomic ion transmembrane transport, calcium ion transmembrane transport, sodium ion transmembrane transport, intracellular calcium ion homeostasis
GO CC Complete:	trans-Golgi network, melanosome, membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Transport of inorganic cations/anions and amino acids/oligopeptides, Transport of small molecules, Sodium/Calcium exchangers, SLC-mediated transmembrane transport

Orthologs

ID	Organism	Type
HUMAN\|HGNC=20611\|UniProtKB=Q71RS6	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000007041.3\|UniProtKB=A0A2J8NTC3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015163.3\|UniProtKB=G3RGP2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000018831.3\|UniProtKB=F6ZB51	Macaca mulatta	LDO
RAT\|RGD=1310565\|UniProtKB=A0A8I6GB53	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000004854.3\|UniProtKB=F1MIZ1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000004662.5\|UniProtKB=A0A4X1SFS1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000032930.3\|UniProtKB=A0A3Q2HAS1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000022887.4\|UniProtKB=M3X5I5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845018687.1\|UniProtKB=A0A8I3NX53	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000002761.4\|UniProtKB=F6YH24	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000050257.1\|UniProtKB=A0A6I8P2D5	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010018219.1\|UniProtKB=A0A8V0Z5G2	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000004764.4\|UniProtKB=H9G9H7	Anolis carolinensis	LDO
XENLA\|Gene=slc24a5.L\|UniProtKB=A0A1L8H0N1	Xenopus laevis	O
XENLA\|Gene=slc24a5.S\|UniProtKB=A0A8J0UQ45	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-853669\|UniProtKB=A0A6I8SU97	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000002760.2\|UniProtKB=A0A3B3ILY0	Oryzias latipes	LDO
DANRE\|Gene=slc24a5\|UniProtKB=Q49SH1	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000013255.1\|UniProtKB=W5N6S0	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118410309\|UniProtKB=A0A9J7KPF4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409489\|UniProtKB=A0A9J7KM11	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC592113\|UniProtKB=A0A7M7N7L9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC580359\|UniProtKB=A0A7M7NBF4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115919082\|UniProtKB=A0A7M7PRH3	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0037238\|UniProtKB=Q9VN12	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP004518\|UniProtKB=Q7PQ73	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC010649\|UniProtKB=A0A139WB83	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_309468\|UniProtKB=E9HCX6	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW010865\|UniProtKB=B7Q4G9	Ixodes scapularis	O
ANOGA\|EnsemblGenome=AGAP010975\|UniProtKB=A7US87	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC013319\|UniProtKB=D6WM88	Tribolium castaneum	O
DROME\|FlyBase=FBgn0039941\|UniProtKB=Q7PLW4	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP010974\|UniProtKB=A0A1S4H695	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP010973\|UniProtKB=A0A1S4H5E6	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC013320\|UniProtKB=D6WM87	Tribolium castaneum	O
DROME\|FlyBase=FBgn0040031\|UniProtKB=A8Y5A2	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0265767\|UniProtKB=Q5LJX8	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029593\|UniProtKB=A0A453Z087	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC014488\|UniProtKB=D6WM86	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_207878\|UniProtKB=E9G011	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW007235\|UniProtKB=B7PW42	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g85050\|UniProtKB=A7RKL4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g198469\|UniProtKB=A7RKL3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g134893\|UniProtKB=A7SW69	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG33154\|UniProtKB=B3SCB1	Trichoplax adhaerens	O
ENTH1\|EnsemblGenome=CL6EHI_018640\|UniProtKB=C4MA70	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=EHI_049410\|UniProtKB=C4LUE3	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_049310\|UniProtKB=C4LUD3	Entamoeba histolytica	O
PARTE\|EnsemblGenome=GSPATT00007604001\|UniProtKB=A0CH97	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00014844001\|UniProtKB=A0DA70	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_4973\|UniProtKB=B8C1L5	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_10292\|UniProtKB=B8CDR0	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_bd1662\|UniProtKB=B8LEG5	Thalassiosira pseudonana	O
NITMS\|EnsemblGenome=Nmar_0590\|UniProtKB=A9A357	Nitrosopumilus maritimus	O
SACS2\|EnsemblGenome=SSO1174\|UniProtKB=Q97YX8	Sulfolobus solfataricus	O
SACS2\|EnsemblGenome=SSO3192\|UniProtKB=Q97U31	Sulfolobus solfataricus	O
METAC\|EnsemblGenome=MA_2817\|UniProtKB=Q8TM51	Methanosarcina acetivorans	O
METAC\|EnsemblGenome=MA_3021\|UniProtKB=Q8TLL5	Methanosarcina acetivorans	O
METAC\|EnsemblGenome=MA_2008\|UniProtKB=Q8TPA6	Methanosarcina acetivorans	O
METJA\|EnsemblGenome=MJ_0091\|UniProtKB=Q57556	Methanocaldococcus jannaschii	O
HALSA\|EnsemblGenome=VNG_2257G\|UniProtKB=Q9HN44	Halobacterium salinarum	O
HALSA\|EnsemblGenome=VNG_0380G\|UniProtKB=Q9HS69	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK0867\|UniProtKB=Q5JI20	Thermococcus kodakaraensis	O
CHLAA\|EnsemblGenome=Caur_1857\|UniProtKB=A9WDA7	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_2211\|UniProtKB=A9WFS0	Chloroflexus aurantiacus	O
THEMA\|EnsemblGenome=TM_0724\|UniProtKB=Q9WZI3	Thermotoga maritima	O
SYNY3\|Gene=P72945_SYNY3\|UniProtKB=P72945	Synechocystis	O
BACTN\|EnsemblGenome=BT_3019\|UniProtKB=Q8A3D5	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB1641\|UniProtKB=Q7UX07	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_066\|UniProtKB=O66480	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A0130\|UniProtKB=B5YHF9	Thermodesulfovibrio yellowstonii	O
COXBU\|EnsemblGenome=CBU_0095\|UniProtKB=Q83F54	Coxiella burnetii	O
SHEON\|Gene_OrderedLocusName=SO_0354\|UniProtKB=Q8EJV2	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_2522\|UniProtKB=Q9KP54	Vibrio cholerae	O
SALTY\|EnsemblGenome=STM3314\|UniProtKB=Q8ZLS2	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO3576\|UniProtKB=A0A2U2H2F5	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE77240\|UniProtKB=P45394	Escherichia coli	O