PANTHER Gene Information

Gene Symbol(s):

CACNA2D1

Organism:

Ornithorhynchus anatinus

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Gene Name:

Calcium voltage-gated channel auxiliary subunit alpha2delta 1

Gene ID:

ENSOANG00000003483.4

Protein ID:

A0A6I8PGU1

Persistent Id:

PTN000018405

Alternate Ids:

A0A6I8PGU1(Synonym)	ENSOANP00000051897(Ensembl_PRO)
XM_007670953(refSeq)	ENSOANG00000003483(Ensembl)
100074856(GeneID)	A0A6I8PGU1_ORNAN(UniProtKB-ID)
ENSOANT00000068124(Ensembl_TRS)	620977754(GI)
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PANTHER Classification

PANTHER Family:	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED (PTHR10166)
PANTHER Subfamily:	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-1 (PTHR10166:SF6)
PANTHER GO-slim Molecular Function:	voltage-gated calcium channel activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	sarcolemma voltage-gated calcium channel complex
PANTHER protein class:	voltage-gated ion channel

Pathway Categories:

Muscarinic acetylcholine receptor 2 and 4 signaling pathway

L-type Calcium Channel

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	voltage-gated calcium channel activity involved in bundle of His cell action potential, calcium channel activity, voltage-gated calcium channel activity
GO BP Complete:	cardiac muscle cell action potential involved in contraction, membrane depolarization during bundle of His cell action potential, calcium ion transport, calcium ion transmembrane transport, cellular response to amyloid-beta, regulation of ventricular cardiac muscle cell membrane repolarization, regulation of heart rate by cardiac conduction, regulation of calcium ion transport, regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
GO CC Complete:	GABA-ergic synapse, T-tubule, L-type voltage-gated calcium channel complex, neuronal dense core vesicle, sarcoplasmic reticulum, membrane, voltage-gated calcium channel complex, presynaptic active zone membrane, monoatomic ion channel complex, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=1399\|UniProtKB=P54289	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000019350.7\|UniProtKB=A0A2I3S420	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000027366.2\|UniProtKB=A0A2I2YH32	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000030244.3\|UniProtKB=A0A1D5QVR4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=88295\|UniProtKB=O08532	Mus musculus	LDO
RAT\|RGD=2247\|UniProtKB=P54290	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000020569.7\|UniProtKB=F1N7F9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000015402.5\|UniProtKB=A0A287BIN3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000010809.4\|UniProtKB=A0A3Q2H0H3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000029914.4\|UniProtKB=A0A2I2UTD9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845026601.1\|UniProtKB=A0A8I3QBI1	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000012063.4\|UniProtKB=A0A5F8GKH5	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000017022.4\|UniProtKB=F6Y0X6	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010010410.1\|UniProtKB=A0A3Q2TVT0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000012663.4\|UniProtKB=G1KNB8	Anolis carolinensis	LDO
XENLA\|Gene=cacna2d1.S\|UniProtKB=A0A8J1MRM7	Xenopus laevis	O
XENLA\|Gene=cacna2d1.L\|UniProtKB=A0A8J1MN54	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-964524\|UniProtKB=A1L1E0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000015164.2\|UniProtKB=H2MK02	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000016214.2\|UniProtKB=H2MNI4	Oryzias latipes	LDO
DANRE\|Gene=cacna2d1a\|UniProtKB=A0A8M3B8Y7	Danio rerio	O
DANRE\|Gene=cacna2d1\|UniProtKB=A0A8M6Z241	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015521.1\|UniProtKB=W5NEQ3	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118416228\|UniProtKB=A0A9J7L7X3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118416201\|UniProtKB=A0A9J7L7V5	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC105441547\|UniProtKB=A0A7M7MZD9	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00007041\|UniProtKB=G5EG74	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG02926\|UniProtKB=A8WT73	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00278310\|UniProtKB=A0A2A6BZ90	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00006772\|UniProtKB=P34374	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG16666\|UniProtKB=A8XP97	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00096769\|UniProtKB=A0A2A6CBK0	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0028863\|UniProtKB=X2J9Z3	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP009598\|UniProtKB=A0A903XHE3	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC001887\|UniProtKB=A0A139WP66	Tribolium castaneum	O
DROME\|FlyBase=FBgn0261999\|UniProtKB=Q8IP22	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP009579\|UniProtKB=A0A1S4H1J5	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC004591\|UniProtKB=D6W834	Tribolium castaneum	O
DROME\|FlyBase=FBgn0261041\|UniProtKB=A0A0B4K866	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP005490\|UniProtKB=A0A1S4GQ08	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC008265\|UniProtKB=D2A0T3	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC034736\|UniProtKB=A0A139WGS5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_324542\|UniProtKB=E9H214	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_317041\|UniProtKB=E9GER3	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG174990\|UniProtKB=T1F8P7	helobdella robusta	O
TRIAD\|EnsemblGenome=TriadG56910\|UniProtKB=B3RWW7	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG56917\|UniProtKB=B3RWX4	Trichoplax adhaerens	O
EMENI\|EnsemblGenome=ANIA_05167\|UniProtKB=Q5B2R3	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G06990\|UniProtKB=Q4WNB0	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU07565\|UniProtKB=Q7S1Y8	Neurospora crassa	O
SELML\|EnsemblGenome=SELMODRAFT_423100\|UniProtKB=D8SKK3	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_402207\|UniProtKB=D8QPX5	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_423098\|UniProtKB=D8SKK1	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_402199\|UniProtKB=D8QPW7	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_423092\|UniProtKB=D8SKJ4	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_402200\|UniProtKB=D8QPW8	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_402202\|UniProtKB=D8QPX0	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c1_25930\|UniProtKB=A0A2K1L9Q7	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c10_3200\|UniProtKB=A0A2K1JXH6	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c2_5170\|UniProtKB=A0A2K1L0A2	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c7_20720\|UniProtKB=A0A2K1KCD4	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c7_19620\|UniProtKB=A0A2K1KC88	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c20_5240\|UniProtKB=A0A2K1IU47	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c22_5320\|UniProtKB=A0A2K1IMC0	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c17_14540\|UniProtKB=A0A7I4B6P4	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0123s0041\|UniProtKB=A0A2R6W9N0	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0009s0226\|UniProtKB=A0A2R6XM14	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0110s0042\|UniProtKB=A0A2R6WCH7	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0123s0042\|UniProtKB=A0A2R6W9N1	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0009s0220\|UniProtKB=A0A2R6XM18	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0200s0010\|UniProtKB=A0A2R6W0N0	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_006550030\|UniProtKB=A0A1Y1IIM7	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_006550020\|UniProtKB=A0A1Y1IKA2	Klebsormidium nitens	O
STRCO\|Gene_OrderedLocusName=SCO2721\|UniProtKB=Q9L1J5	Streptomyces coelicolor	O
CLOBH\|Gene_OrderedLocusName=CBO3213\|UniProtKB=A5I6U2	Clostridium botulinum	O
CLOBH\|Gene_OrderedLocusName=CBO0552\|UniProtKB=A5HZ97	Clostridium botulinum	O
BACTN\|EnsemblGenome=BT_4465\|UniProtKB=Q89ZB2	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB7099\|UniProtKB=Q7UP85	Rhodopirellula baltica	O
SHEON\|Gene_OrderedLocusName=SO_3552\|UniProtKB=Q8EBG6	Shewanella oneidensis	O
XANCP\|EnsemblGenome=XCC2915\|UniProtKB=Q8P6Q2	Xanthomonas campestris	O
SALTY\|EnsemblGenome=STM2315\|UniProtKB=Q8ZNE5	Salmonella typhimurium	O
ECOLI\|EnsemblGenome=BAE76678\|UniProtKB=P76481	Escherichia coli	O