PANTHER Gene Information   
Gene Symbol(s): HDAC3
Organism: Sus scrofa
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Gene Name: Histone deacetylase 3
Gene ID: ENSSSCG00000014388.5
Protein ID: A0A287B575
Persistent Id: PTN001318780
Alternate Ids:
A0A287B575_PIG(UniProtKB-ID) A0A287B575(Synonym)
ENSSSCG00000014388(Ensembl) ENSSSCT00000047350(Ensembl_TRS)
ENSSSCP00000051591(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: HISTONE DEACETYLASE HDAC1-RELATED (PTHR10625)
PANTHER Subfamily: HISTONE DEACETYLASE 3 (PTHR10625:SF36)  
PANTHER GO-slim Molecular Function: histone deacetylase activity
PANTHER GO-slim Biological Process: epigenetic regulation of gene expression
PANTHER GO-slim Cellular Component:
PANTHER protein class:
Pathway Categories: Wnt signaling pathway
   Histone deacetylase
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: chromatin DNA binding, histone deacetylase binding, tubulin deacetylase activity, histone H3K4 deacetylase activity, hydrolytic mechanism, transcription corepressor binding, NF-kappaB binding, histone H4K8 deacetylase activity, hydrolytic mechanism, histone H4K16 deacetylase activity, hydrolytic mechanism, histone H4K5 deacetylase activity, hydrolytic mechanism, histone H4K12 deacetylase activity, hydrolytic mechanism, histone deacetylase activity, histone decrotonylase activity, transcription corepressor activity, metal ion binding, cyclin binding, protein de-2-hydroxyisobutyrylase activity, histone H3K14 deacetylase activity, hydrolytic mechanism, histone H3K9 deacetylase activity, hydrolytic mechanism
GO BP Complete: regulation of multicellular organism growth, positive regulation of protein import into nucleus, cornified envelope assembly, neural precursor cell proliferation, transcription by RNA polymerase II, regulation of circadian rhythm, positive regulation of transcription by RNA polymerase II, negative regulation of JNK cascade, regulation of mitotic cell cycle, epigenetic regulation of gene expression, establishment of skin barrier, negative regulation of transcription by RNA polymerase II, establishment of mitotic spindle orientation, spindle assembly, circadian regulation of gene expression, regulation of protein stability, in utero embryonic development, random inactivation of X chromosome, cellular response to fluid shear stress, negative regulation of cardiac muscle cell differentiation, positive regulation of protein ubiquitination, DNA repair-dependent chromatin remodeling, positive regulation of cold-induced thermogenesis, positive regulation of TOR signaling
GO CC Complete: mitotic spindle, transcription repressor complex, histone deacetylase complex, cytosol, Golgi apparatus, chromatin, plasma membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Metabolism, Signaling by ALK, Signal Transduction, Developmental Biology, STAT3 nuclear events downstream of ALK signaling, Chromatin organization, Notch-HLH transcription pathway, Gene expression (Transcription), Metabolism of lipids, Regulation of lipid metabolism by PPARalpha, NR1H2 and NR1H3-mediated signaling, Generic Transcription Pathway, HDACs deacetylate histones, Signaling by Receptor Tyrosine Kinases, NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux, Signaling by Nuclear Receptors, Chromatin modifying enzymes, Transcriptional regulation of white adipocyte differentiation, RNA Polymerase II Transcription

Orthologs