PANTHER Gene Information   
Gene Symbol(s): NFATC3
Organism: Sus scrofa
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Gene Name: Nuclear factor of activated T cells 3
Gene ID: ENSSSCG00000029578.4
Protein ID: A0A287B5I3
Persistent Id: PTN008997602
Alternate Ids:
A0A287B5I3(Synonym) ENSSSCG00000029578(Ensembl)
ENSSSCP00000051545(Ensembl_PRO) A0A287B5I3_PIG(UniProtKB-ID)
ENSSSCT00000048178(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: NFAT (PTHR12533)
PANTHER Subfamily: NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3 (PTHR12533:SF6)  
PANTHER GO-slim Molecular Function: DNA-binding transcription factor activity, RNA polymerase II-specific
transcription factor binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process: regulation of transcription by RNA polymerase II
calcineurin-mediated signaling
cytokine production
PANTHER GO-slim Cellular Component: transcription regulator complex
PANTHER protein class: Rel homology transcription factor
Pathway Categories: T cell activation
   Nuclear factor of activated T cells
Inflammation mediated by chemokine and cytokine signaling pathway
   Nuclear factor of activated T cells
Gonadotropin-releasing hormone receptor pathway
   NFAT
B cell activation
   Nuclear factor of activated T cells
Wnt signaling pathway
   Nuclear factor of activated T-cells
Axon guidance mediated by netrin
   Nuclear factor of activated T-cells
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, transcription factor binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete: negative regulation of transcription by RNA polymerase II, calcineurin-NFAT signaling cascade, negative regulation of miRNA transcription, cytokine production, positive regulation of transcription by RNA polymerase II, negative regulation of vascular associated smooth muscle cell differentiation, regulation of transcription by RNA polymerase II
GO CC Complete: transcription regulator complex, cytosol, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Downstream signaling events of B Cell Receptor (BCR), Fc epsilon receptor (FCERI) signaling, CLEC7A (Dectin-1) induces NFAT activation, Immune System, C-type lectin receptors (CLRs), FCERI mediated Ca+2 mobilization, Calcineurin activates NFAT, Innate Immune System, CLEC7A (Dectin-1) signaling, Adaptive Immune System, Signaling by the B Cell Receptor (BCR)

Orthologs