PANTHER Gene Information

Gene Symbol(s):

nfatc3

Organism:

Xenopus tropicalis

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Gene Name:

Nuclear factor of activated T-cells, cytoplasmic 3

Gene ID:

XB-GENE-493918

Protein ID:

B4F6V2

Persistent Id:

PTN008997608

Alternate Ids:

XM_018092947(refSeq)	1043424852(GI)
ENSXETP00000012789(Ensembl_PRO)	100216091(GeneID)
B4F6V2(Synonym)	ENSXETT00000007515(Ensembl_TRS)
AAI68023(EMBL-CDS)	BC168023(EMBL)
B4F6V2_XENTR(UniProtKB-ID)	ENSXETG00000005812(Ensembl)
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PANTHER Classification

PANTHER Family:	NFAT (PTHR12533)
PANTHER Subfamily:	NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3 (PTHR12533:SF6)
PANTHER GO-slim Molecular Function:	DNA-binding transcription factor activity, RNA polymerase II-specific transcription factor binding RNA polymerase II cis-regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process:	regulation of transcription by RNA polymerase II calcineurin-mediated signaling cytokine production
PANTHER GO-slim Cellular Component:	transcription regulator complex
PANTHER protein class:	Rel homology transcription factor

Pathway Categories:

T cell activation

Nuclear factor of activated T cells

Inflammation mediated by chemokine and cytokine signaling pathway

Nuclear factor of activated T cells

Gonadotropin-releasing hormone receptor pathway

NFAT

B cell activation

Nuclear factor of activated T cells

Wnt signaling pathway

Nuclear factor of activated T-cells

Axon guidance mediated by netrin

Nuclear factor of activated T-cells

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, DNA-binding transcription factor activity
GO BP Complete:	regulation of DNA-templated transcription
GO CC Complete:	nucleus, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Innate Immune System, FCERI mediated Ca+2 mobilization, Immune System, C-type lectin receptors (CLRs), CLEC7A (Dectin-1) signaling, CLEC7A (Dectin-1) induces NFAT activation, Fc epsilon receptor (FCERI) signaling

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7777\|UniProtKB=Q12968	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000008260.6\|UniProtKB=K7DDW5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010145.3\|UniProtKB=G3R3R8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000021843.4\|UniProtKB=F7EIB3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=103296\|UniProtKB=P97305	Mus musculus	LDO
RAT\|RGD=1308692\|UniProtKB=A0A0G2JTY4	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000004368.6\|UniProtKB=F1MSU2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000029578.4\|UniProtKB=A0A287B5I3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000014089.4\|UniProtKB=A0A3Q2HAK2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000030997.4\|UniProtKB=M3X7E0	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000005276.3\|UniProtKB=A0A5F8G5Z7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000021344.3\|UniProtKB=F6S104	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010021335.1\|UniProtKB=A0A1D5P8S9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000009839.4\|UniProtKB=H9GFR3	Anolis carolinensis	LDO
XENLA\|Gene=nfatc3.L\|UniProtKB=A0A1L8GK58	Xenopus laevis	O
XENLA\|Gene=nfatc3.S\|UniProtKB=Q8QHM1	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000027634.1\|UniProtKB=A0A3B3HZY7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000011964.2\|UniProtKB=H2M909	Oryzias latipes	LDO
DANRE\|Gene=nfatc3b\|UniProtKB=A0A8M3APB5	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-041111-41\|UniProtKB=E7FE12	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000008087.1\|UniProtKB=W5MN63	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118418168\|UniProtKB=A0A9J7LBQ8	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC590859\|UniProtKB=A0A7M7LTI6	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0030505\|UniProtKB=A8JUV3	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP013287\|UniProtKB=A0A453YYJ4	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC014708\|UniProtKB=D6WNZ3	Tribolium castaneum	O
IXOSC\|EnsemblGenome=ISCW023728\|UniProtKB=B7QHC8	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g243338\|UniProtKB=A7S787	Nematostella vectensis	O