PANTHER Gene Information

Gene Symbol(s):

Mpo

Organism:

Rattus norvegicus

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Gene Name:

Myeloperoxidase

Gene ID:

1592081

Protein ID:

A0A0G2K1A2

Persistent Id:

PTN002263235

Alternate Ids:

A0A0G2K1A2(Synonym)	ENSRNOG00000008310(Ensembl)
ENSRNOT00000081951(Ensembl_TRS)	XM_006247095(refSeq)
1592081(RGD)	ENSRNOP00000071759(Ensembl_PRO)
A0A0G2K1A2_RAT(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	OXIDASE/PEROXIDASE (PTHR11475)
PANTHER Subfamily:	MYELOPEROXIDASE (PTHR11475:SF108)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on peroxide as acceptor antioxidant activity
PANTHER GO-slim Biological Process:	defense response to bacterium
PANTHER GO-slim Cellular Component:	extracellular space
PANTHER protein class:	peroxidase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	peroxidase activity, metal ion binding, heparin binding, heme binding
GO BP Complete:	response to food, low-density lipoprotein particle remodeling, defense response to bacterium, response to mechanical stimulus, hydrogen peroxide catabolic process, response to oxidative stress, hypochlorous acid biosynthetic process, response to gold nanoparticle, respiratory burst involved in defense response, response to yeast, removal of superoxide radicals, response to lipopolysaccharide, defense response to fungus
GO CC Complete:	extracellular space, secretory granule, intracellular membrane-bounded organelle, azurophil granule, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Neutrophil degranulation, ROS and RNS production in phagocytes, Immune System, Innate Immune System, Events associated with phagocytolytic activity of PMN cells

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7218\|UniProtKB=P05164	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000009449.6\|UniProtKB=H2QDI9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000016705.3\|UniProtKB=A0A2I2ZML3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000002266.4\|UniProtKB=F7BAA9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97137\|UniProtKB=P11247	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000011616.6\|UniProtKB=A6QPT4	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000017637.6\|UniProtKB=K7GRV6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000006662.4\|UniProtKB=F7BZ88	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000012263.6\|UniProtKB=M3WGL9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845018435.1\|UniProtKB=A0A8I3P7A7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000014737.4\|UniProtKB=A0A5F8G344	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000013085.2\|UniProtKB=A0A6I8N0T1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010029571.1\|UniProtKB=A0A8V1AP82	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000000090.3\|UniProtKB=H9G386	Anolis carolinensis	O
XENLA\|Gene=mpo.L\|UniProtKB=Q8QFX3	Xenopus laevis	O
XENLA\|Gene=mpo.S\|UniProtKB=A0A8J1MD77	Xenopus laevis	O
XENTR\|Gene=mpo\|UniProtKB=A0A8J0QMK7	Xenopus tropicalis	O
XENLA\|Gene=epx.L\|UniProtKB=B7ZR75	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-6039946\|UniProtKB=A0A8J0QNI7	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000023289.1\|UniProtKB=A0A3B3I439	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000029520.1\|UniProtKB=A0A3B3HEP2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000027810.1\|UniProtKB=A0A3B3HIJ5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000009349.2\|UniProtKB=H2LZT8	Oryzias latipes	O
DANRE\|Gene=epx\|UniProtKB=A0A8M9PHJ3	Danio rerio	O
DANRE\|Gene=mpx\|UniProtKB=A0A8M1P4H4	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000015220.1\|UniProtKB=W5NDM5	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000007217.1\|UniProtKB=W5MK29	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000002735.3\|UniProtKB=F6TPL8	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000001200.3\|UniProtKB=F6TKP0	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000007419.3\|UniProtKB=F7B882	Ciona intestinalis	O
BRAFL\|Gene=LOC118405423\|UniProtKB=A0A9J7KI86	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421694\|UniProtKB=A0A9J7MYR9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118410320\|UniProtKB=A0A9J7KPR3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118405412\|UniProtKB=A0A9J7HM94	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC593243\|UniProtKB=A0A7M7NRT7	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00004256\|UniProtKB=Q1ENI8	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG01526\|UniProtKB=A8WQH2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00112475\|UniProtKB=A0A2A6C1L5	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00022743\|UniProtKB=Q23490	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG03680\|UniProtKB=A8WVK8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00112969\|UniProtKB=A0A2A6B3L1	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00009897\|UniProtKB=Q20616	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00024013\|UniProtKB=A8WND4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00112337\|UniProtKB=A0A2A6D383	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00015841\|UniProtKB=P91060	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00037311\|UniProtKB=A8XRR7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00278329\|UniProtKB=A0A2A6BYY8	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00017968\|UniProtKB=H2KZ53	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG13113\|UniProtKB=A8XH40	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00273835\|UniProtKB=A0A2A6B853	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00004257\|UniProtKB=G5EG78	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG17537\|UniProtKB=A8XR70	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00100463\|UniProtKB=A0A2A6C2W5	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0011828\|UniProtKB=Q9VZZ4	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007237\|UniProtKB=A0A1S4GUJ9	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC001556\|UniProtKB=D6WFS4	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_318324\|UniProtKB=E9GIG8	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW022537\|UniProtKB=B7QCX2	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG89299\|UniProtKB=T1G7B8	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g110667\|UniProtKB=A7SA38	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG22758\|UniProtKB=B3RSQ8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG27445\|UniProtKB=B3S2M4	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_26049\|UniProtKB=A9V180	Monosiga brevicollis	O
DICDI\|dictyBase=DDB_G0277275\|UniProtKB=Q6TMK4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_83593\|UniProtKB=F1A000	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_95122\|UniProtKB=F0ZSF2	Dictyostelium purpureum	O
THAPS\|EnsemblGenome=THAPSDRAFT_267958\|UniProtKB=B8BPZ7	Thalassiosira pseudonana	O
GLOVI\|Gene=Q7NFC7_GLOVI\|UniProtKB=Q7NFC7	Gloeobacter violaceus	O
RHOBA\|EnsemblGenome=RB4293\|UniProtKB=Q7USU5	Rhodopirellula baltica	O
BRADU\|Gene=Q89E60_BRADU\|UniProtKB=Q89E60	Bradyrhizobium diazoefficiens	O