PANTHER Gene Information

Gene Symbol(s):

Pxn

Organism:

Drosophila melanogaster

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Gene Name:

Peroxidasin

Gene ID:

FBgn0011828

Protein ID:

Q9VZZ4

Persistent Id:

PTN000158927

Alternate Ids:

24656157(GI)	PXDN(Synonym)
Pxn{ECO:0000312\|FlyBase:FBgn0011828}(Symbol)	38326(GeneID)
AY051536(EMBL)	AAK92960(EMBL-CDS)
FBgn0011828(FlyBase)	PXDN_DROME(UniProtKB-ID)
1.11.2.- {ECO:0000269\|PubMed:22842973}(EC)	Q961K8(AltAccession)
FBgn0011828(Ensembl)
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PANTHER Classification

PANTHER Family:	OXIDASE/PEROXIDASE (PTHR11475)
PANTHER Subfamily:	PEROXIDASIN (PTHR11475:SF58)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on peroxide as acceptor antioxidant activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	peroxidase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	peroxidase activity, oxidoreductase activity, acting on peroxide as acceptor, heme binding
GO BP Complete:	response to oxidative stress, phagocytosis, extracellular matrix organization, basement membrane assembly, collagen fibril organization
GO CC Complete:	extracellular space, collagen-containing extracellular matrix

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Thyroxine biosynthesis, ROS and RNS production in phagocytes, Metabolism, Immune System, Events associated with phagocytolytic activity of PMN cells, Innate Immune System, Metabolism of amine-derived hormones, Metabolism of amino acids and derivatives, Neutrophil degranulation

Orthologs

ID	Organism	Type
MONDO\|Ensembl=ENSMODG00000019169.4\|UniProtKB=A0A5F8GV99	Monodelphis domestica	O
CHICK\|Ensembl=ENSGALG00010029565.1\|UniProtKB=A0A8V1AP72	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000013406.4\|UniProtKB=A0A803SXX8	Anolis carolinensis	O
HUMAN\|HGNC=7218\|UniProtKB=P05164	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000009449.6\|UniProtKB=H2QDI9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000016705.3\|UniProtKB=A0A2I2ZML3	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000002266.4\|UniProtKB=F7BAA9	Macaca mulatta	O
MOUSE\|MGI=MGI=97137\|UniProtKB=P11247	Mus musculus	O
RAT\|RGD=1592081\|UniProtKB=A0A0G2K1A2	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000011616.6\|UniProtKB=A6QPT4	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000017637.6\|UniProtKB=K7GRV6	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000006662.4\|UniProtKB=F7BZ88	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000012263.6\|UniProtKB=M3WGL9	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845018435.1\|UniProtKB=A0A8I3P7A7	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000014737.4\|UniProtKB=A0A5F8G344	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000013085.2\|UniProtKB=A0A6I8N0T1	Ornithorhynchus anatinus	O
HUMAN\|HGNC=6678\|UniProtKB=P22079	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000009448.5\|UniProtKB=H2QDI8	Pan troglodytes	O
MACMU\|Ensembl=ENSMMUG00000002264.4\|UniProtKB=F7BAC5	Macaca mulatta	O
MOUSE\|MGI=MGI=1923363\|UniProtKB=Q5SW46	Mus musculus	O
RAT\|RGD=1310051\|UniProtKB=D4A400	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000012780\|UniProtKB=P80025	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000017636.6\|UniProtKB=A0A4X1SLW4	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000023550.4\|UniProtKB=F7C3Z3	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000012262.6\|UniProtKB=M3WGL8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845018202.1\|UniProtKB=A0A8I3P5G5	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000014744.3\|UniProtKB=F6YN88	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000008483.3\|UniProtKB=F7CCN5	Ornithorhynchus anatinus	O
HUMAN\|HGNC=3423\|UniProtKB=P11678	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000009446.5\|UniProtKB=H2QDI6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000003135.3\|UniProtKB=G3QKU8	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000011973.4\|UniProtKB=F7H275	Macaca mulatta	O
MOUSE\|MGI=MGI=107569\|UniProtKB=P49290	Mus musculus	O
RAT\|RGD=1311882\|UniProtKB=D3ZSY4	Rattus norvegicus	O
PIG\|Ensembl=ENSSSCG00000017630.5\|UniProtKB=F1RSB4	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000017317.4\|UniProtKB=F6RBT1	Equus caballus	O
CANLF\|Ensembl=ENSCAFG00845017713.1\|UniProtKB=A0A8I3NYF9	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000014755.4\|UniProtKB=A0A5F8GRK9	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000040563.1\|UniProtKB=F6YEM5	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010029571.1\|UniProtKB=A0A8V1AP82	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000000090.3\|UniProtKB=H9G386	Anolis carolinensis	O
XENLA\|Gene=mpo.L\|UniProtKB=Q8QFX3	Xenopus laevis	O
XENLA\|Gene=mpo.S\|UniProtKB=A0A8J1MD77	Xenopus laevis	O
XENTR\|Gene=mpo\|UniProtKB=A0A8J0QMK7	Xenopus tropicalis	O
XENLA\|Gene=epx.L\|UniProtKB=B7ZR75	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-6039946\|UniProtKB=A0A8J0QNI7	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000023289.1\|UniProtKB=A0A3B3I439	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000029520.1\|UniProtKB=A0A3B3HEP2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000027810.1\|UniProtKB=A0A3B3HIJ5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000009349.2\|UniProtKB=H2LZT8	Oryzias latipes	O
DANRE\|Gene=epx\|UniProtKB=A0A8M9PHJ3	Danio rerio	O
DANRE\|Gene=mpx\|UniProtKB=A0A8M1P4H4	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000015220.1\|UniProtKB=W5NDM5	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000007217.1\|UniProtKB=W5MK29	lepisosteus oculatus	O
HUMAN\|HGNC=12015\|UniProtKB=P07202	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000049999.1\|UniProtKB=A0A2I3SH53	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000004239.4\|UniProtKB=G3QNP8	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000009662.4\|UniProtKB=F6ZA88	Macaca mulatta	O
MOUSE\|MGI=MGI=98813\|UniProtKB=P35419	Mus musculus	O
RAT\|RGD=3900\|UniProtKB=P14650	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000055050.1\|UniProtKB=A0A3Q1M790	Bos taurus	O
PIG\|Gene=TPO\|UniProtKB=P09933	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000033193.3\|UniProtKB=A0A287AZ10	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000025046.3\|UniProtKB=F6QKN1	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000002875.6\|UniProtKB=A0A2I2U1B1	Felis catus	O
CANLF\|Gene=TPO\|UniProtKB=Q8HYB7	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845017327.1\|UniProtKB=A0A8I3PAJ8	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000014296.4\|UniProtKB=F6WJN9	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000009858.3\|UniProtKB=A0A6I8PEN1	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010002300.1\|UniProtKB=A0A8V0XEQ0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000005443.4\|UniProtKB=G1KE77	Anolis carolinensis	O
XENLA\|Gene=tpo.S\|UniProtKB=A0A8J1KRZ9	Xenopus laevis	O
XENTR\|Gene=tpo\|UniProtKB=A0A8J1JL56	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000017591.2\|UniProtKB=H2MTA8	Oryzias latipes	O
DANRE\|Gene=tpo\|UniProtKB=A0A8M9PP20	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000016428.1\|UniProtKB=W5NI32	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000002735.3\|UniProtKB=F6TPL8	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000001200.3\|UniProtKB=F6TKP0	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000007419.3\|UniProtKB=F7B882	Ciona intestinalis	O
BRAFL\|Gene=LOC118405423\|UniProtKB=A0A9J7KI86	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421694\|UniProtKB=A0A9J7MYR9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118410320\|UniProtKB=A0A9J7KPR3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118405412\|UniProtKB=A0A9J7HM94	Branchiostoma floridae	O
HUMAN\|HGNC=26359\|UniProtKB=A1KZ92	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020241.5\|UniProtKB=H2QW54	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000014572.3\|UniProtKB=G3RQA0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000002781.4\|UniProtKB=A0A5F7ZWY1	Macaca mulatta	LDO
HORSE\|Ensembl=ENSECAG00000022817.4\|UniProtKB=F6WE58	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000005332.5\|UniProtKB=M3W3W4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845029236.1\|UniProtKB=A0A8I3Q2P6	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000009863.4\|UniProtKB=F6VTX1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000007271.4\|UniProtKB=F7CKI9	Ornithorhynchus anatinus	LDO
LEPOC\|Ensembl=ENSLOCG00000005932.1\|UniProtKB=W5MFK7	lepisosteus oculatus	LDO
HUMAN\|HGNC=14966\|UniProtKB=Q92626	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000011612.5\|UniProtKB=K7D7S6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000012776.3\|UniProtKB=G3RAK7	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000039871.2\|UniProtKB=A0A5F8A9Z4	Macaca mulatta	O
MOUSE\|MGI=MGI=1916925\|UniProtKB=Q3UQ28	Mus musculus	O
RAT\|RGD=1560694\|UniProtKB=A0A0G2JWB6	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000050986.1\|UniProtKB=A0A3Q1LMN6	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000029570.4\|UniProtKB=I3LDA4	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000019739.4\|UniProtKB=A0A9L0TF86	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000008327.6\|UniProtKB=A0A2I2V044	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845017525.1\|UniProtKB=A0A8I3P3Y3	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000014304.4\|UniProtKB=F6W4P8	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000009860.3\|UniProtKB=F6ZT49	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010023230.1\|UniProtKB=A0A8V0ZZQ7	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000006172.4\|UniProtKB=G1KF53	Anolis carolinensis	O
CHICK\|Ensembl=ENSGALG00010003388.1\|UniProtKB=A0A8V0XDJ1	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000005554.4\|UniProtKB=G1KEG3	Anolis carolinensis	O
XENLA\|Gene=pxdn.L\|UniProtKB=A0A1L8GBD8	Xenopus laevis	O
XENLA\|Gene=pxdn.S\|UniProtKB=A0A1L8G530	Xenopus laevis	O
ORYLA\|Ensembl=ENSORLG00000017847.2\|UniProtKB=H2MU79	Oryzias latipes	O
DANRE\|Gene=pxdn\|UniProtKB=A0A8M3AJA6	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000017217.1\|UniProtKB=W5NKX8	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000006970.3\|UniProtKB=F6SYX7	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118432218\|UniProtKB=A0A9J7ME95	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC593243\|UniProtKB=A0A7M7NRT7	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00004256\|UniProtKB=Q1ENI8	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG01526\|UniProtKB=A8WQH2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00112475\|UniProtKB=A0A2A6C1L5	Pristionchus pacificus	LDO
CAEEL\|WormBase=WBGene00022743\|UniProtKB=Q23490	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG03680\|UniProtKB=A8WVK8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00112969\|UniProtKB=A0A2A6B3L1	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00009897\|UniProtKB=Q20616	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00024013\|UniProtKB=A8WND4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00112337\|UniProtKB=A0A2A6D383	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00015841\|UniProtKB=P91060	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00037311\|UniProtKB=A8XRR7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00278329\|UniProtKB=A0A2A6BYY8	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00017968\|UniProtKB=H2KZ53	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG13113\|UniProtKB=A8XH40	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00273835\|UniProtKB=A0A2A6B853	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00004257\|UniProtKB=G5EG78	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG17537\|UniProtKB=A8XR70	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00100463\|UniProtKB=A0A2A6C2W5	Pristionchus pacificus	O
ANOGA\|EnsemblGenome=AGAP007237\|UniProtKB=A0A1S4GUJ9	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC001556\|UniProtKB=D6WFS4	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_318324\|UniProtKB=E9GIG8	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW022537\|UniProtKB=B7QCX2	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG89299\|UniProtKB=T1G7B8	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g110667\|UniProtKB=A7SA38	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG22758\|UniProtKB=B3RSQ8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG27445\|UniProtKB=B3S2M4	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_26049\|UniProtKB=A9V180	Monosiga brevicollis	O
DICDI\|dictyBase=DDB_G0277275\|UniProtKB=Q6TMK4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_83593\|UniProtKB=F1A000	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_95122\|UniProtKB=F0ZSF2	Dictyostelium purpureum	O
THAPS\|EnsemblGenome=THAPSDRAFT_267958\|UniProtKB=B8BPZ7	Thalassiosira pseudonana	O
GLOVI\|Gene=Q7NFC7_GLOVI\|UniProtKB=Q7NFC7	Gloeobacter violaceus	O
RHOBA\|EnsemblGenome=RB4293\|UniProtKB=Q7USU5	Rhodopirellula baltica	O
BRADU\|Gene=Q89E60_BRADU\|UniProtKB=Q89E60	Bradyrhizobium diazoefficiens	O