PANTHER Gene Information

Gene Symbol(s):

Tpo

Organism:

Rattus norvegicus

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Gene Name:

Thyroid peroxidase

Gene ID:

3900

Protein ID:

P14650

Persistent Id:

PTN000158854

Alternate Ids:

3900(RGD)	AAA42265(EMBL-CDS)
Tpo(Symbol)	PERT(Synonym)
X17396(EMBL)	129832(GI)
PERT_RAT(UniProtKB-ID)	1.11.1.8 {ECO:0000250\|UniProtKB:P09933}(EC)
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PANTHER Classification

PANTHER Family:	OXIDASE/PEROXIDASE (PTHR11475)
PANTHER Subfamily:	THYROID PEROXIDASE (PTHR11475:SF60)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on peroxide as acceptor antioxidant activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	extracellular space
PANTHER protein class:	peroxidase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	iodide peroxidase activity, peroxidase activity, calcium ion binding, heme binding
GO BP Complete:	response to oxidative stress, embryonic hemopoiesis, thyroid hormone generation, cellular response to nitric oxide, cellular oxidant detoxification, response to lipid, hormone biosynthetic process, hydrogen peroxide catabolic process
GO CC Complete:	extracellular space, membrane, cell surface

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism of amine-derived hormones, Metabolism, Thyroxine biosynthesis, Metabolism of amino acids and derivatives

Orthologs

ID	Organism	Type
HUMAN\|HGNC=12015\|UniProtKB=P07202	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000049999.1\|UniProtKB=A0A2I3SH53	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004239.4\|UniProtKB=G3QNP8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000009662.4\|UniProtKB=F6ZA88	Macaca mulatta	LDO
MOUSE\|MGI=MGI=98813\|UniProtKB=P35419	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000055050.1\|UniProtKB=A0A3Q1M790	Bos taurus	LDO
PIG\|Gene=TPO\|UniProtKB=P09933	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000033193.3\|UniProtKB=A0A287AZ10	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000025046.3\|UniProtKB=F6QKN1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000002875.6\|UniProtKB=A0A2I2U1B1	Felis catus	LDO
CANLF\|Gene=TPO\|UniProtKB=Q8HYB7	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845017327.1\|UniProtKB=A0A8I3PAJ8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000014296.4\|UniProtKB=F6WJN9	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000009858.3\|UniProtKB=A0A6I8PEN1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010002300.1\|UniProtKB=A0A8V0XEQ0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000005443.4\|UniProtKB=G1KE77	Anolis carolinensis	LDO
XENLA\|Gene=tpo.S\|UniProtKB=A0A8J1KRZ9	Xenopus laevis	LDO
XENTR\|Gene=tpo\|UniProtKB=A0A8J1JL56	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000017591.2\|UniProtKB=H2MTA8	Oryzias latipes	LDO
DANRE\|Gene=tpo\|UniProtKB=A0A8M9PP20	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000016428.1\|UniProtKB=W5NI32	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000002735.3\|UniProtKB=F6TPL8	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000001200.3\|UniProtKB=F6TKP0	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000007419.3\|UniProtKB=F7B882	Ciona intestinalis	O
BRAFL\|Gene=LOC118405423\|UniProtKB=A0A9J7KI86	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421694\|UniProtKB=A0A9J7MYR9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118410320\|UniProtKB=A0A9J7KPR3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118405412\|UniProtKB=A0A9J7HM94	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC593243\|UniProtKB=A0A7M7NRT7	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00004256\|UniProtKB=Q1ENI8	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG01526\|UniProtKB=A8WQH2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00112475\|UniProtKB=A0A2A6C1L5	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00022743\|UniProtKB=Q23490	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG03680\|UniProtKB=A8WVK8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00112969\|UniProtKB=A0A2A6B3L1	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00009897\|UniProtKB=Q20616	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00024013\|UniProtKB=A8WND4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00112337\|UniProtKB=A0A2A6D383	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00015841\|UniProtKB=P91060	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00037311\|UniProtKB=A8XRR7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00278329\|UniProtKB=A0A2A6BYY8	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00017968\|UniProtKB=H2KZ53	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG13113\|UniProtKB=A8XH40	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00273835\|UniProtKB=A0A2A6B853	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00004257\|UniProtKB=G5EG78	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG17537\|UniProtKB=A8XR70	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00100463\|UniProtKB=A0A2A6C2W5	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0011828\|UniProtKB=Q9VZZ4	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007237\|UniProtKB=A0A1S4GUJ9	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC001556\|UniProtKB=D6WFS4	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_318324\|UniProtKB=E9GIG8	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW022537\|UniProtKB=B7QCX2	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG89299\|UniProtKB=T1G7B8	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g110667\|UniProtKB=A7SA38	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG22758\|UniProtKB=B3RSQ8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG27445\|UniProtKB=B3S2M4	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_26049\|UniProtKB=A9V180	Monosiga brevicollis	O
DICDI\|dictyBase=DDB_G0277275\|UniProtKB=Q6TMK4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_83593\|UniProtKB=F1A000	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_95122\|UniProtKB=F0ZSF2	Dictyostelium purpureum	O
THAPS\|EnsemblGenome=THAPSDRAFT_267958\|UniProtKB=B8BPZ7	Thalassiosira pseudonana	O
GLOVI\|Gene=Q7NFC7_GLOVI\|UniProtKB=Q7NFC7	Gloeobacter violaceus	O
RHOBA\|EnsemblGenome=RB4293\|UniProtKB=Q7USU5	Rhodopirellula baltica	O
BRADU\|Gene=Q89E60_BRADU\|UniProtKB=Q89E60	Bradyrhizobium diazoefficiens	O