PANTHER Gene Information   
Gene Symbol(s): Dpyd
Organism: Rattus norvegicus
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Gene Name: Dihydropyrimidine dehydrogenase [NADP(+)]
Gene ID: 621218
Protein ID: O89000
Persistent Id: PTN000234120
Alternate Ids:
81656(GeneID) 621218(RGD)
Dpyd{ECO:0000312|RGD:621218}(Symbol) DHPDHase(Synonym)
D85035(EMBL) BAA33218(EMBL-CDS)
1.3.1.2 {ECO:0000250|UniProtKB:Q12882}(EC) 13591940(GI)
NP_112289(refSeq) MetaCyc:MON-15405(BioCyc)
DPYD_RAT(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)] (PTHR43073)
PANTHER Subfamily: DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)] (PTHR43073:SF2)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class: dehydrogenase
Pathway Categories: Pyrimidine Metabolism
   Dihydrouracil Dehydrogenase
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: nucleotide binding, FAD binding, identical protein binding, NADP binding, protein homodimerization activity, FMN binding, iron ion binding, metal ion binding, flavin adenine dinucleotide binding, dihydropyrimidine dehydrogenase (NADP+) activity, 4 iron, 4 sulfur cluster binding, uracil binding
GO BP Complete: purine nucleobase catabolic process, uracil catabolic process, response to nutrient, thymine catabolic process, response to xenobiotic stimulus, response to organic cyclic compound, CMP catabolic process, circadian rhythm, dCMP catabolic process, thymidine catabolic process, pyrimidine nucleobase catabolic process, beta-alanine biosynthetic process, dUMP catabolic process, response to glucocorticoid, uracil metabolic process, UMP catabolic process
GO CC Complete: cytoplasm, cytosol
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Metabolism of nucleotides, Metabolism, Pyrimidine catabolism, Nucleotide catabolism

Orthologs