PANTHER Gene Information   
Gene Symbol(s): pka1
Organism: Schizosaccharomyces pombe
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Gene Name: cAMP-dependent protein kinase catalytic subunit
Gene ID: SPBC106.10
Protein ID: P40376
Persistent Id: PTN000682792
Alternate Ids:
2.7.11.11(EC) NP_595159(refSeq)
SPBC106(Ensembl) 729868(GI)
CAB53726(EMBL-CDS) D23667(EMBL)
tpk(Synonym) SPBC106.10(Ensembl_TRS)
SPBC106.10.1:pep(Ensembl_PRO) pka1(Symbol)
KAPB_SCHPO(UniProtKB-ID) 2539781(GeneID)
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PANTHER Classification
PANTHER Family: CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE (PTHR24353)
PANTHER Subfamily: CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT 1 (PTHR24353:SF153)  
PANTHER GO-slim Molecular Function: protein serine/threonine kinase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component: cytosol
serine/threonine protein kinase complex
intracellular protein-containing complex
nucleus
PANTHER protein class: non-receptor serine/threonine protein kinase
Pathway Categories: Metabotropic glutamate receptor group I pathway
   Protein kinase A
Metabotropic glutamate receptor group II pathway
   Protein kinase A
Inflammation mediated by chemokine and cytokine signaling pathway
   Protein kinase A
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
   Protein kinase A
Endothelin signaling pathway
   Protein kinase A
Enkephalin release
   Protein kinase A
Beta1 adrenergic receptor signaling pathway
   Protein kinase A
Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction
   Protein kinase A
Dopamine receptor mediated signaling pathway
   Protein kinase A
5HT1 type receptor mediated signaling pathway
   Protein kinase A
Metabotropic glutamate receptor group III pathway
   Protein kinase A
Histamine H2 receptor mediated signaling pathway
   Protein kinase A
Beta2 adrenergic receptor signaling pathway
   Protein kinase A
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP binding, protein binding, cAMP-dependent protein kinase activity, protein serine/threonine kinase activity
GO BP Complete: negative regulation of transcription by RNA polymerase II, adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway, positive regulation of protein export from nucleus, signal transduction, negative regulation of induction of conjugation with cellular fusion, negative regulation of gluconeogenesis, adenylate cyclase-activating G protein-coupled receptor signaling pathway, positive regulation of microtubule depolymerization
GO CC Complete: nucleus, cytoplasm, cytosol, fungal-type vacuole, cAMP-dependent protein kinase complex, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: G alpha (i) signalling events, PKA activation in glucagon signalling, Vasopressin regulates renal water homeostasis via Aquaporins, Integration of energy metabolism, GPCR downstream signalling, CREB1 phosphorylation through the activation of Adenylate Cyclase, Aquaporin-mediated transport, Signaling by Hedgehog, Post NMDA receptor activation events, Transport of small molecules, Signaling by GPCR, GPER1 signaling, PKA activation, Transmission across Chemical Synapses, Opioid Signalling, Neurotransmitter receptors and postsynaptic signal transmission, DARPP-32 events, Neuronal System, Hedgehog 'off' state, G alpha (s) signalling events, DAG and IP3 signaling, Factors involved in megakaryocyte development and platelet production, Intracellular signaling by second messengers, Activation of NMDA receptors and postsynaptic events, Glucagon signaling in metabolic regulation, Ca-dependent events, Hemostasis, PKA-mediated phosphorylation of CREB, CaM pathway, Metabolism, Signal Transduction, Calmodulin induced events, G-protein mediated events, Mitochondrial protein degradation, PLC beta mediated events, Metabolism of proteins

Orthologs