PANTHER Gene Information   
Gene Symbol(s): prkaca
Organism: Xenopus tropicalis
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Gene Name: cAMP-dependent protein kinase
Gene ID: XB-GENE-5954970
Protein ID: A0A6I8SXB5
Persistent Id: PTN008614650
Alternate Ids:
1043430079(GI) A0A6I8SXB5(Synonym)
XP_012808518(refSeq) ENSXETT00000071352(Ensembl_TRS)
ENSXETP00000097827(Ensembl_PRO) ENSXETG00000022849(Ensembl)
549157(GeneID) A0A6I8SXB5_XENTR(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE (PTHR24353)
PANTHER Subfamily: CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA (PTHR24353:SF82)  
PANTHER GO-slim Molecular Function: protein serine/threonine kinase activity
protein kinase A regulatory subunit binding
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component: cytosol
serine/threonine protein kinase complex
intracellular protein-containing complex
nucleus
PANTHER protein class: non-receptor serine/threonine protein kinase
Pathway Categories: Inflammation mediated by chemokine and cytokine signaling pathway
   Protein kinase A
Metabotropic glutamate receptor group II pathway
   Protein kinase A
GABA-B receptor II signaling
   Protein kinase A
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
   Protein kinase A
CCKR signaling map
   PKA-Calpha/beta/gamma
Endothelin signaling pathway
   Protein kinase A
Enkephalin release
   Protein kinase A
Beta1 adrenergic receptor signaling pathway
   Protein kinase A
Histamine H2 receptor mediated signaling pathway
   Protein kinase A
Beta2 adrenergic receptor signaling pathway
   Protein kinase A
Metabotropic glutamate receptor group I pathway
   Protein kinase A
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   Protein kinase A, catalytic subunit
Nicotine pharmacodynamics pathway
   cAMP-dependent protein kinase catalytic subunit alpha
Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction
   Protein kinase A
5HT1 type receptor mediated signaling pathway
   Protein kinase A
Dopamine receptor mediated signaling pathway
   Protein kinase A
Metabotropic glutamate receptor group III pathway
   Protein kinase A
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP binding, protein kinase A regulatory subunit binding, cAMP-dependent protein kinase activity, protein serine/threonine kinase activity
GO BP Complete: signal transduction
GO CC Complete: nucleus, cytoplasm, mitochondrion, cytosol, plasma membrane, cAMP-dependent protein kinase complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: GLI3 is processed to GLI3R by the proteasome, Centrosome maturation, Recruitment of NuMA to mitotic centrosomes, Hedgehog 'off' state, Mitotic G2-G2/M phases, PKA activation, Mitotic Prometaphase, Loss of proteins required for interphase microtubule organization from the centrosome, Metabolism, PKA-mediated phosphorylation of CREB, Adaptive Immune System, Calmodulin induced events, Factors involved in megakaryocyte development and platelet production, GPER1 signaling, VEGFA-VEGFR2 Pathway, Intracellular signaling by second messengers, Mitochondrial protein degradation, Signaling by Hedgehog, Loss of Nlp from mitotic centrosomes, Hemostasis, Regulation of insulin secretion, Transport of small molecules, DARPP-32 events, Organelle biogenesis and maintenance, Neuronal System, Anchoring of the basal body to the plasma membrane, Signaling by Receptor Tyrosine Kinases, Transmission across Chemical Synapses, Cilium Assembly, Neurotransmitter receptors and postsynaptic signal transmission, Plasma lipoprotein assembly, Plasma lipoprotein assembly, remodeling, and clearance, Signaling by GPCR, HDL assembly, Signal Transduction, G-protein mediated events, Activation of NMDA receptors and postsynaptic events, PLC beta mediated events, Glucagon-like Peptide-1 (GLP1) regulates insulin secretion, Signaling by VEGF, Cell Cycle, DAG and IP3 signaling, Glucagon signaling in metabolic regulation, Cell Cycle, Mitotic, Metabolism of proteins, G2/M Transition, CaM pathway, Ca-dependent events, Cardiac conduction, Regulation of PLK1 Activity at G2/M Transition, Aquaporin-mediated transport, PKA activation in glucagon signalling, CREB1 phosphorylation through the activation of Adenylate Cyclase, G alpha (s) signalling events, Vasopressin regulates renal water homeostasis via Aquaporins, Integration of energy metabolism, Immune System, Ion homeostasis, G alpha (i) signalling events, Rap1 signalling, Recruitment of mitotic centrosome proteins and complexes, Post NMDA receptor activation events, M Phase, GPCR downstream signalling, AURKA Activation by TPX2, Opioid Signalling, Muscle contraction

Orthologs