PANTHER Gene Information

Gene Symbol(s):

Tb07.28B13.710

Organism:

Trypanosoma brucei

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Tree

Gene Name:

Farnesyl pyrophosphate synthase

Gene ID:

Tb927.7.3360

Protein ID:

Q57WF1

Persistent Id:

PTN002264105

Alternate Ids:

XP_845959(refSeq)	AC159429(EMBL)
62175946(GI)	AAX70070(EMBL-CDS)
Q57WF1(Synonym)	3658548(GeneID)
Q57WF1_TRYB2(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	FARNESYL-PYROPHOSPHATE SYNTHETASE (PTHR11525)
PANTHER Subfamily:	FARNESYL PYROPHOSPHATE SYNTHASE (PTHR11525:SF0)
PANTHER GO-slim Molecular Function:	prenyltransferase activity
PANTHER GO-slim Biological Process:	terpenoid biosynthetic process phospholipid biosynthetic process
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	acyltransferase

Pathway Categories:

Cholesterol biosynthesis

Geranyl trans-transferase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	geranyltranstransferase activity, dimethylallyltranstransferase activity
GO BP Complete:	cholesterol biosynthetic process, farnesyl diphosphate biosynthetic process
GO CC Complete:	cytoplasm, cytosol, endoplasmic reticulum

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3631\|UniProtKB=P14324	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000001422.5\|UniProtKB=H2Q079	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000023144.4\|UniProtKB=F7FI27	Macaca mulatta	LDO
MOUSE\|MGI=MGI=104888\|UniProtKB=Q920E5	Mus musculus	LDO
RAT\|RGD=68953\|UniProtKB=P05369	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000006512.5\|UniProtKB=A0A287AWX3	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000039350.3\|UniProtKB=A0A5F5XN41	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845011910.1\|UniProtKB=A0A8I3NF82	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000019060.3\|UniProtKB=H9H792	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010028374.1\|UniProtKB=A0A8V1AK88	Gallus gallus	LDO
CHICK\|Gene=FDPS\|UniProtKB=P08836	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003450.3\|UniProtKB=H9G7J1	Anolis carolinensis	LDO
XENLA\|Gene=fdps.S\|UniProtKB=A0A1L8F590	Xenopus laevis	O
XENLA\|Gene=fdps.L\|UniProtKB=A0A1L8FDJ2	Xenopus laevis	LDO
XENTR\|Gene=fdps\|UniProtKB=A0A8J1ILE9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000010041.2\|UniProtKB=H2M2F4	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050506-78\|UniProtKB=Q4V916	Danio rerio	LDO
CIOIN\|Ensembl=ENSCING00000008276.3\|UniProtKB=F6QHP8	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118409624\|UniProtKB=A0A9J7KMF8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC576515\|UniProtKB=A0A7M7T2B7	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00011058\|UniProtKB=O62336	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00038065\|UniProtKB=A8XTW8	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00304433\|UniProtKB=A0A8R1V2Y2	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0025373\|UniProtKB=Q7KN61	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP007104\|UniProtKB=Q7QIW5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC009256\|UniProtKB=D6WSE7	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC009257\|UniProtKB=D6WSE5	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_313317\|UniProtKB=E9G2F8	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW009264\|UniProtKB=B7Q0Y1	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG115552\|UniProtKB=T1EG91	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g185913\|UniProtKB=A7S5I7	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG31406\|UniProtKB=B3S8W6	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_6210\|UniProtKB=A9UT59	Monosiga brevicollis	LDO
YEAST\|SGD=S000003703\|UniProtKB=P08524	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AEL122W\|UniProtKB=Q757Y2	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000188232\|UniProtKB=A0A1D8PH78	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E05753g\|UniProtKB=Q6C6W3	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_08012\|UniProtKB=Q5AUL8	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G02450\|UniProtKB=Q4WEB8	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU01175\|UniProtKB=Q92250	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_07659\|UniProtKB=A7EQQ6	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_15418\|UniProtKB=Q0TY86	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC36.06c\|UniProtKB=O59703	Schizosaccharomyces pombe	O
SCHPO\|PomBase=SPAC6F12.13c\|UniProtKB=O14230	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_00580\|UniProtKB=B6JW13	Schizosaccharomyces japonicus	O
SCHJY\|EnsemblGenome=SJAG_03352\|UniProtKB=B6K405	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNE04510\|UniProtKB=Q5KG83	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_11875\|UniProtKB=A0A0D1E775	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_16289\|UniProtKB=E3L168	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_00514\|UniProtKB=E3JPU5	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_17386\|UniProtKB=F4P7S3	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0268742\|UniProtKB=Q55EU7	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_150024\|UniProtKB=F0ZF95	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0278823\|UniProtKB=Q54XP1	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0278735\|UniProtKB=Q9NH03	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_38391\|UniProtKB=F0ZUD6	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_38388\|UniProtKB=F0ZUD8	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_147615\|UniProtKB=F0Z8Y9	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_22_1360\|UniProtKB=Q4QBL1	Leishmania major	LDO
GIAIC\|EnsemblGenome=GL50803_6633\|UniProtKB=A8B433	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_388030\|UniProtKB=A2E130	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_150090\|UniProtKB=A2DRR1	Trichomonas vaginalis	LDO
TRIV3\|Gene_ORFName=TVAG_353270\|UniProtKB=A2EN50	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_1128400\|UniProtKB=Q8II79	Plasmodium falciparum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_30105\|UniProtKB=B8CD36	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3HB70_PHYRM\|UniProtKB=H3HB70	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_03g207700v5\|UniProtKB=A8IX41	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00061p00181710\|UniProtKB=U5DFJ8	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_70G00610\|UniProtKB=A0A0K9NSK0	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_112G00130\|UniProtKB=A0A0K9Q373	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma03_g29760\|UniProtKB=A0A804IHU0	Musa acuminata subsp. malaccensis	LDO
MUSAM\|EnsemblGenome=Ma09_g22750\|UniProtKB=A0A804KML5	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_022190mg\|UniProtKB=K3Z6M1	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3006G248000\|UniProtKB=A0A1B6PNS2	Sorghum bicolor	O
ORYSJ\|EnsemblGenome=Os04g0657100\|UniProtKB=Q0J9F2	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_5g24640v3\|UniProtKB=I1J2U5	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0202590\|UniProtKB=A0A8I6XHJ3	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS2A02G501900\|UniProtKB=A0A3B6B6C0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2B02G530100\|UniProtKB=A0A3B6CGW5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G502400\|UniProtKB=A0A3B6DL43	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_022312mg\|UniProtKB=K3Z6Z2	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3009G216800\|UniProtKB=C5YUX0	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb342550\|UniProtKB=P49353	Zea mays	O
ORYSJ\|EnsemblGenome=Os05g0543400\|UniProtKB=Q65XM9	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_2g17990v3\|UniProtKB=I1HGY9	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0079800\|UniProtKB=F2D4M6	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS1B02G383400\|UniProtKB=A0A3B5Z2T1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G371200\|UniProtKB=A0A3B5ZZS4	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1A02G365800\|UniProtKB=A0A3B5Y680	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_002022mg\|UniProtKB=K3XJE9	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3003G270500\|UniProtKB=C5XHL1	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb361070\|UniProtKB=K7V8H3	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb155590\|UniProtKB=B4FVE3	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os01g0695300\|UniProtKB=Q5N9P6	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_2g47310v3\|UniProtKB=I1HQM7	Brachypodium distachyon	O
WHEAT\|EnsemblGenome=TraesCS3A02G258600\|UniProtKB=A0A3B6EHL0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3D02G258500\|UniProtKB=A0A3B6GUI1	Triticum aestivum	O
ORYSJ\|EnsemblGenome=Os01g0703400\|UniProtKB=O04882	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g47610v3\|UniProtKB=I1HQR4	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0283300\|UniProtKB=F2CPK7	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS3B02G286300\|UniProtKB=L7PE91	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3A02G254300\|UniProtKB=A0A3B6ELC1	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS3D02G255200\|UniProtKB=A0A3B6GXJ4	Triticum aestivum	LDO
NELNU\|Gene=LOC104588689\|UniProtKB=A0A1U7Z2Y6	Nelumbo nucifera	LDO
NELNU\|Gene=LOC104594300\|UniProtKB=A0A1U7ZWG2	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110800321\|UniProtKB=A0A9R0K7F6	Spinacia oleracea	O
SPIOL\|Gene=LOC110782066\|UniProtKB=A0A9R0I2X6	Spinacia oleracea	O
SPIOL\|Gene=LOC110782060\|UniProtKB=A0A9R0I3I2	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr08g0350351\|UniProtKB=A0A251U7H3	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr05g0234511\|UniProtKB=A0A251UT80	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C700387540\|UniProtKB=A0A9R1V2M3	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C500229030\|UniProtKB=A0A9R1VJI8	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a026653mg\|UniProtKB=A0A022QAV5	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a008270mg\|UniProtKB=A0A022R0F5	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_08678\|UniProtKB=A0A1U8G2J5	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400029788\|UniProtKB=M1CX22	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc12g015860.2\|UniProtKB=O65004	Solanum lycopersicum	O
TOBAC\|Gene=LOC107779968\|UniProtKB=A0A1S3YVG4	Nicotiana tabacum	O
TOBAC\|Gene=LOC107806551\|UniProtKB=A0A1S4BBL2	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_24642\|UniProtKB=A0A1U8EE36	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400014369\|UniProtKB=M1B520	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc10g005840.3\|UniProtKB=A0A3Q7I9T2	Solanum lycopersicum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400008690\|UniProtKB=M1AGP3	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc10g005820.2\|UniProtKB=A0A3Q7IB68	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107795792\|UniProtKB=A0A1S4ABD1	Nicotiana tabacum	O
TOBAC\|Gene=LOC107765018\|UniProtKB=A0A1S3XHA2	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi19g00729\|UniProtKB=D7UAM1	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_E03835\|UniProtKB=A0A059C9Z7	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00001929001\|UniProtKB=A0A078FXF0	Brassica napus	O
BRACM\|EnsemblGenome=Bra024917\|UniProtKB=M4E811	Brassica campestris	O
BRANA\|EnsemblGenome=GSBRNA2T00069140001\|UniProtKB=A0A078JML3	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00041597001\|UniProtKB=A0A078GUT9	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra022156\|UniProtKB=M4E059	Brassica campestris	LDO
ARATH\|TAIR=locus=2130654\|UniProtKB=Q43315	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2160947\|UniProtKB=Q09152	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107944620\|UniProtKB=A0A1U8N805	Gossypium hirsutum	O
GOSHI\|Gene=LOC107922380\|UniProtKB=A0A1U8KZP6	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_030583\|UniProtKB=A0A061F3M2	Theobroma cacao	O
GOSHI\|Gene=LOC107905737\|UniProtKB=A0A1U8JH25	Gossypium hirsutum	O
GOSHI\|Gene=FPS2\|UniProtKB=A0A1B1HY16	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_030459\|UniProtKB=A0A061GGK8	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g019339mg\|UniProtKB=A0A067EVX1	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_006G003400v3\|UniProtKB=A9PFL3	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_03G143700\|UniProtKB=A0A140GWW3	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0523370\|UniProtKB=B9S9Y3	Ricinus communis	O
MANES\|EnsemblGenome=MANES_08G076500\|UniProtKB=A0A2C9VEA9	Manihot esculenta	LDO
MANES\|EnsemblGenome=MANES_09G084500\|UniProtKB=A0A140GWW1	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0426460\|UniProtKB=B9T7W9	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_20G047100\|UniProtKB=K7N1M8	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_09G015600\|UniProtKB=I1L053	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_15G121400\|UniProtKB=I1MFU1	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_2g027300\|UniProtKB=G7IQ36	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr09_16640\|UniProtKB=A0A2I4EST8	Juglans regia	O
JUGRE\|EnsemblGenome=Jr02_26210\|UniProtKB=A0A2I4E293	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_7G278210\|UniProtKB=A0A0A0K997	Cucumis sativus	O
JUGRE\|Gene=LOC108996553\|UniProtKB=A0A6P9ENX6	Juglans regia	O
JUGRE\|EnsemblGenome=Jr04_12380\|UniProtKB=A0A2I4G0H5	Juglans regia	O
JUGRE\|EnsemblGenome=Jr03_13240\|UniProtKB=A0A2I4F8S5	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_6G017060\|UniProtKB=A0A0A0K801	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_6G028100\|UniProtKB=M5VZ02	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_4G002700\|UniProtKB=A0A251PDK8	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_234027\|UniProtKB=D8SGZ0	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_127038\|UniProtKB=D8SX77	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_420677\|UniProtKB=D8SCS0	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_173042\|UniProtKB=D8RNV9	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_236261\|UniProtKB=D8T6V9	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_159144\|UniProtKB=D8SXE9	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c24_18700\|UniProtKB=A9SPQ1	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0024s0031\|UniProtKB=A0A2R6XBL8	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_002870200\|UniProtKB=A0A1Y1ICH6	Klebsormidium nitens	LDO