PANTHER Gene Information

Gene Symbol(s):

mitf

Organism:

Xenopus tropicalis

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Gene Name:

Microphthalmia-associated transcription factor

Gene ID:

XB-GENE-484962

Protein ID:

A4IID0

Persistent Id:

PTN008697895

Alternate Ids:

100101790(GeneID)	AAI35969(EMBL-CDS)
A4IID0_XENTR(UniProtKB-ID)	154147684(GI)
BC135968(EMBL)	NM_001100277(refSeq)
A4IID0(Synonym)
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PANTHER Classification

PANTHER Family:	MIP04163P (PTHR45776)
PANTHER Subfamily:	MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR (PTHR45776:SF4)
PANTHER GO-slim Molecular Function:	DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process:	regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	basic helix-loop-helix transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, protein dimerization activity, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	melanocyte differentiation, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II
GO CC Complete:	nucleus, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism of proteins, SUMOylation, SUMOylation of transcription factors, Post-translational protein modification, SUMO E3 ligases SUMOylate target proteins

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7105\|UniProtKB=O75030	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000015100.5\|UniProtKB=A0A2I3RWW4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000024338.2\|UniProtKB=A0A2I2YQK2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000002100.4\|UniProtKB=H9ELZ8	Macaca mulatta	LDO
MOUSE\|MGI=MGI=104554\|UniProtKB=Q08874	Mus musculus	LDO
RAT\|RGD=3092\|UniProtKB=O88368	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000006679.7\|UniProtKB=A0A3Q1MKP6	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000011514.5\|UniProtKB=D2JUK3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000005360.4\|UniProtKB=F6ZKQ4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000024419.4\|UniProtKB=A0A2I2UHM0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845009666.1\|UniProtKB=A0A8I3N265	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000003754.4\|UniProtKB=F7DV34	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000012406.4\|UniProtKB=F7DUA0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010022062.1\|UniProtKB=A0A3Q2U6P0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000036061.1\|UniProtKB=A0A803TPW1	Anolis carolinensis	LDO
XENLA\|Gene=mitf.S\|UniProtKB=A0A8J0V374	Xenopus laevis	O
XENLA\|Gene=Mitf-M\|UniProtKB=Q76DN3	Xenopus laevis	O
XENLA\|Gene=mitf.L\|UniProtKB=Q76DN4	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000003123.2\|UniProtKB=K9L437	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000013461.2\|UniProtKB=A0A3B3HNN5	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-990910-11\|UniProtKB=Q9PWC2	Danio rerio	LDO
DANRE\|ZFIN=ZDB-GENE-010919-1\|UniProtKB=F1Q885	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000010058.1\|UniProtKB=W5MV93	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004702.3\|UniProtKB=F6QNF1	Ciona intestinalis	O
BRAFL\|Gene=LOC118415416\|UniProtKB=A0A9J7MPM9	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC577766\|UniProtKB=A0A7M7RDY6	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00020930\|UniProtKB=H2KZZ2	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00042922\|UniProtKB=H8WHA0	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG05364\|UniProtKB=A8WZP5	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00202776\|UniProtKB=A0A2A6BYJ1	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0263112\|UniProtKB=C3KGP2	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP000807\|UniProtKB=A7USK4	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC014225\|UniProtKB=A0A139WP70	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_96359\|UniProtKB=E9FXN6	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW011795\|UniProtKB=B7Q780	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW011796\|UniProtKB=B7Q781	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG180867\|UniProtKB=T1FGC6	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g240998\|UniProtKB=A7RVM3	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG60032\|UniProtKB=B3S741	Trichoplax adhaerens	O
YEAST\|SGD=S000000199\|UniProtKB=P38165	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ADR067W\|UniProtKB=Q75A52	Eremothecium gossypii	O
YARLI\|EnsemblGenome=YALI0_F11979g\|UniProtKB=Q6C201	Yarrowia lipolytica	O