PANTHER Gene Information   
Gene Symbol(s): rac2
Organism: Xenopus tropicalis
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Gene Name: Novel protein similar to ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1)
Gene ID: XB-GENE-494950
Protein ID: Q5M8J2
Persistent Id: PTN008604833
Alternate Ids:
BC087999(EMBL) Q5M8J2_XENTR(UniProtKB-ID)
NM_001011285(refSeq) 89272958(GI)
CAJ82940(EMBL-CDS) ENSXETG00000004629(Ensembl)
ENSXETT00000016252(Ensembl_TRS) 496738(GeneID)
ENSXETP00000016252(Ensembl_PRO) Q5M8J2(Synonym)
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PANTHER Classification
PANTHER Family: RHO FAMILY GTPASE (PTHR24072)
PANTHER Subfamily: RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2 (PTHR24072:SF169)  
PANTHER GO-slim Molecular Function: protein kinase binding
GTPase activity
carbohydrate derivative binding
anion binding
nucleotide binding
PANTHER GO-slim Biological Process: regulation of cell shape
cortical cytoskeleton organization
establishment or maintenance of cell polarity
regulation of actin cytoskeleton organization
PANTHER GO-slim Cellular Component: cell projection
cytoskeleton
cytoplasmic vesicle
PANTHER protein class: small GTPase
Pathway Categories: VEGF signaling pathway
   Ras-related C3 botulinum toxin substrate
FGF signaling pathway
   Ras-related C3 botulinum toxin substrate
Integrin signalling pathway
   Ras-related C3 botulinum toxin substrate
Axon guidance mediated by Slit/Robo
   Ras-related C3 botulinum toxin substrate
Inflammation mediated by chemokine and cytokine signaling pathway
   Cell division cycle 42
p38 MAPK pathway
   Ras-related C3 botulinum toxin substrate
Huntington disease
   Ras-related C3 botulinum toxin substrate
B cell activation
   Ras-related C3 botulinum toxin substrate
T cell activation
   Ras-related C3 botulinum toxin substrate
Axon guidance mediated by netrin
   Ras-related C3 botulinum toxin substrate
Axon guidance mediated by semaphorins
   Ras-related C3 botulinum toxin substrate
Cytoskeletal regulation by Rho GTPase
   Ras-related C3 Botulinum toxin substrate 1
Ras Pathway
   Ras-related C3 botulinum toxin substrate
EGF receptor signaling pathway
   Ras-related C3 botulinum toxin substrate

GO MF Complete: GTP binding, protein kinase binding, GTPase activity
GO BP Complete: regulation of cell shape, positive regulation of lamellipodium assembly, chemotaxis, cortical cytoskeleton organization, regulation of actin cytoskeleton organization, signal transduction, small GTPase-mediated signal transduction, establishment or maintenance of cell polarity, regulation of neutrophil migration, actin filament organization
GO CC Complete: cytoskeleton, cytoplasmic vesicle, cell projection, plasma membrane
Reactome Pathways: Signal Transduction, Innate Immune System, Signaling by Rho GTPases, Hemostasis, Immune System, ROS and RNS production in phagocytes, RHO GTPases Activate NADPH Oxidases, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, PCP/CE pathway, Beta-catenin independent WNT signaling, RHO GTPase cycle, RAC2 GTPase cycle, PIP3 activates AKT signaling, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, GPVI-mediated activation cascade, RHO GTPase Effectors, Signaling by WNT, Platelet activation, signaling and aggregation, Negative regulation of the PI3K/AKT network, Intracellular signaling by second messengers