Pathway Component Details
| Name: | Ras-related C3 botulinum toxin substrate (rac) |
| Definition: | Rac is a monomeric GTPase that undergoes nucleotide exchange upon interacting with the GEF, vav. Rac-GTP regulates actin cytoskeletal dynamics through its interaction with PAK, and through incompletely characterized means promotes MEKK activity. |
| Category ID: | P01324 |
| Synonyms: | |
| Upstream: | |
| Downstream: | |
| Number Families/Subfamilies: | 5 |
| Number of Associated Sequences: | 11 |
| GO Molecular Function: |
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| GO Biological Process: |
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| GO Cellular Component: |
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| PANTHER protein class: |
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| References: |
Sequence Association
| Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
| PTHR24072:SF105 | A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | PubMed:10891487 |
| A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | PubMed:12676940 | |
| A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | PubMed:12874273 | |
| A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | PubMed:12912997 | |
| A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | PubMed:12932731 | |
| A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | PubMed:14564011 | |
| A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | PubMed:15470041 | |
| A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | 4757952 | |
| A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | PubMed:8649368 | |
| Q29RC5 | Rac family small GTPase 1b | ISS | PubMed:10891487 | |
| Q29RC5 | Rac family small GTPase 1b | ISS | PubMed:12676940 | |
| Q29RC5 | Rac family small GTPase 1b | ISS | PubMed:12874273 | |
| Q29RC5 | Rac family small GTPase 1b | ISS | PubMed:12912997 | |
| Q29RC5 | Rac family small GTPase 1b | ISS | PubMed:12932731 | |
| Q29RC5 | Rac family small GTPase 1b | ISS | PubMed:14564011 | |
| Q29RC5 | Rac family small GTPase 1b | ISS | PubMed:15470041 | |
| Q29RC5 | Rac family small GTPase 1b | ISS | 4757952 | |
| Q29RC5 | Rac family small GTPase 1b | ISS | PubMed:8649368 | |
| Q7ZSZ9 | Rac family small GTPase 1a | ISS | PubMed:10891487 | |
| Q7ZSZ9 | Rac family small GTPase 1a | ISS | PubMed:12676940 | |
| Q7ZSZ9 | Rac family small GTPase 1a | ISS | PubMed:12932731 | |
| Q7ZSZ9 | Rac family small GTPase 1a | ISS | PubMed:14564011 | |
| Q7ZSZ9 | Rac family small GTPase 1a | ISS | PubMed:21244534 | |
| Q7ZSZ9 | Rac family small GTPase 1a | ISS | 4757952 | |
| Q7ZSZ9 | Rac family small GTPase 1a | ISS | PubMed:8649368 | |
| PTHR24072:SF169 | A0A8I6A1P8 | Rac family small GTPase 2 | ISS | PubMed:10802295 |
| A0A8I6A1P8 | Rac family small GTPase 2 | ISS | PubMed:10891487 | |
| A0A8I6A1P8 | Rac family small GTPase 2 | ISS | PubMed:12176041 | |
| A0A8I6A1P8 | Rac family small GTPase 2 | ISS | PubMed:12676940 | |
| A0A8I6A1P8 | Rac family small GTPase 2 | ISS | PubMed:12932731 | |
| A0A8I6A1P8 | Rac family small GTPase 2 | ISS | PubMed:12960248 | |
| A0A8I6A1P8 | Rac family small GTPase 2 | ISS | PubMed:14564011 | |
| A0A8I6A1P8 | Rac family small GTPase 2 | ISS | PubMed:20264070 | |
| A0A8I6A1P8 | Rac family small GTPase 2 | ISS | 4757952 | |
| Q05144 | Ras-related C3 botulinum toxin substrate 2 | ISS | PubMed:10802295 | |
| Q05144 | Ras-related C3 botulinum toxin substrate 2 | ISS | PubMed:10891487 | |
| Q05144 | Ras-related C3 botulinum toxin substrate 2 | ISS | PubMed:12176041 | |
| Q05144 | Ras-related C3 botulinum toxin substrate 2 | ISS | PubMed:12676940 | |
| Q05144 | Ras-related C3 botulinum toxin substrate 2 | ISS | PubMed:12932731 | |
| Q05144 | Ras-related C3 botulinum toxin substrate 2 | ISS | PubMed:12960248 | |
| Q05144 | Ras-related C3 botulinum toxin substrate 2 | ISS | PubMed:14564011 | |
| Q05144 | Ras-related C3 botulinum toxin substrate 2 | ISS | PubMed:20264070 | |
| Q05144 | Ras-related C3 botulinum toxin substrate 2 | ISS | 4757952 | |
| PTHR24072:SF325 | Q6DGB7 | Rac family small GTPase 3a | ISS | PubMed:10891487 |
| Q6DGB7 | Rac family small GTPase 3a | ISS | PubMed:12676940 | |
| Q6DGB7 | Rac family small GTPase 3a | ISS | PubMed:12874273 | |
| Q6DGB7 | Rac family small GTPase 3a | ISS | PubMed:12912997 | |
| Q6DGB7 | Rac family small GTPase 3a | ISS | PubMed:12932731 | |
| Q6DGB7 | Rac family small GTPase 3a | ISS | PubMed:14564011 | |
| Q6DGB7 | Rac family small GTPase 3a | ISS | PubMed:15470041 | |
| Q6DGB7 | Rac family small GTPase 3a | ISS | 4757952 | |
| Q6DGB7 | Rac family small GTPase 3a | ISS | PubMed:8649368 | |
| PTHR24072:SF359 | C3YJC1 | Ras-related C3 botulinum toxin substrate 1 | ISS | |
| PTHR24072:SF395 | A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | PubMed:10891487 |
| A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | PubMed:12676940 | |
| A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | PubMed:12874273 | |
| A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | PubMed:12912997 | |
| A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | PubMed:12932731 | |
| A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | PubMed:14564011 | |
| A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | PubMed:15470041 | |
| A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | 4757952 | |
| A0A8V0Z8U4 | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | ISS | PubMed:8649368 | |
| P63000 | Ras-related C3 botulinum toxin substrate 1 | IDA | PubMed:10891487 | |
| P63000 | Ras-related C3 botulinum toxin substrate 1 | IDA | PubMed:12676940 | |
| P63000 | Ras-related C3 botulinum toxin substrate 1 | IDA | PubMed:12932731 | |
| P63000 | Ras-related C3 botulinum toxin substrate 1 | IDA | PubMed:14564011 | |
| P63000 | Ras-related C3 botulinum toxin substrate 1 | IDA | PubMed:21244534 | |
| P63000 | Ras-related C3 botulinum toxin substrate 1 | IDA | 4757952 | |
| P63000 | Ras-related C3 botulinum toxin substrate 1 | IDA | PubMed:8649368 | |
| P63001 | Ras-related C3 botulinum toxin substrate 1 | ISS | PubMed:10891487 | |
| P63001 | Ras-related C3 botulinum toxin substrate 1 | ISS | PubMed:12676940 | |
| P63001 | Ras-related C3 botulinum toxin substrate 1 | ISS | PubMed:12932731 | |
| P63001 | Ras-related C3 botulinum toxin substrate 1 | ISS | PubMed:14564011 | |
| P63001 | Ras-related C3 botulinum toxin substrate 1 | ISS | PubMed:21244534 | |
| P63001 | Ras-related C3 botulinum toxin substrate 1 | ISS | 4757952 | |
| P63001 | Ras-related C3 botulinum toxin substrate 1 | ISS | PubMed:8649368 | |
| Q6RUV5 | Ras-related C3 botulinum toxin substrate 1 | ISS | PubMed:10891487 | |
| Q6RUV5 | Ras-related C3 botulinum toxin substrate 1 | ISS | PubMed:12676940 | |
| Q6RUV5 | Ras-related C3 botulinum toxin substrate 1 | ISS | PubMed:12932731 | |
| Q6RUV5 | Ras-related C3 botulinum toxin substrate 1 | ISS | PubMed:14564011 | |
| Q6RUV5 | Ras-related C3 botulinum toxin substrate 1 | ISS | PubMed:21244534 | |
| Q6RUV5 | Ras-related C3 botulinum toxin substrate 1 | ISS | 4757952 | |
| Q6RUV5 | Ras-related C3 botulinum toxin substrate 1 | ISS | PubMed:8649368 |
