PANTHER Gene Information   
Gene Symbol(s): pik3r3
Organism: Xenopus tropicalis
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Gene Name: Phosphatidylinositol 3-kinase regulatory subunit gamma
Gene ID: XB-GENE-6464721
Protein ID: Q28IS1
Persistent Id: PTN008494594
Alternate Ids:
Q28IS1_XENTR(UniProtKB-ID) NM_001017229(refSeq)
ENSXETP00000007065(Ensembl_PRO) 549983(GeneID)
89268740(GI) CR760256(EMBL)
ENSXETT00000007065(Ensembl_TRS) ENSXETG00000003253(Ensembl)
CAJ82419(EMBL-CDS) Q28IS1(Synonym)
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PANTHER Classification
PANTHER Family: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT (PTHR10155)
PANTHER Subfamily: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT GAMMA (PTHR10155:SF2)  
PANTHER GO-slim Molecular Function: kinase regulator activity
PANTHER GO-slim Biological Process: phosphatidylinositol phosphate biosynthetic process
insulin receptor signaling pathway
PANTHER GO-slim Cellular Component: phosphatidylinositol 3-kinase complex
PANTHER protein class: kinase modulator
Pathway Categories: VEGF signaling pathway
   Phosphatidylinositol 3-kinase
PI3 kinase pathway
   p85
T cell activation
   Phosphatidylinositol 3-kinase
Hypoxia response via HIF activation
   Phosphatidylinositol 3-kinase
Insulin/IGF pathway-protein kinase B signaling cascade
   Phosphatidylinositol 3-kinase
Angiogenesis
   Phosphatidylinositol 3-kinase
Integrin signalling pathway
   Phosphatidylinositol 3-kinase
Axon guidance mediated by netrin
   Phosphatidylinositol 3-kinase
Endothelin signaling pathway
   Phosphatidylinositol 3-kinase
PDGF signaling pathway
   Phosphatidylinositol 3-kinase
p53 pathway feedback loops 2
   Phosphatidylinositol 3-kinase
p53 pathway
   Phosphatidylinositol 3-kinase
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: kinase activity, 1-phosphatidylinositol-3-kinase regulator activity
GO BP Complete: insulin receptor signaling pathway
GO CC Complete: phosphatidylinositol 3-kinase complex, class IA
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Signal Transduction, Signaling by Rho GTPases, Costimulation by the CD28 family, Synthesis of PIPs at the plasma membrane, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, CD28 dependent PI3K/Akt signaling, CD28 co-stimulation, Metabolism, RET signaling, Cytokine Signaling in Immune system, Signaling by Interleukins, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, Adaptive Immune System, GPVI-mediated activation cascade, Regulation of signaling by CBL, Negative regulation of the PI3K/AKT network, Nervous system development, Signaling by SCF-KIT, Intracellular signaling by second messengers, PI Metabolism, G alpha (q) signalling events, Hemostasis, Immune System, Phospholipid metabolism, Axon guidance, Metabolism of lipids, RHO GTPase cycle, GPCR downstream signalling, RAC2 GTPase cycle, Interleukin-3, Interleukin-5 and GM-CSF signaling, PIP3 activates AKT signaling, RAC1 GTPase cycle, Developmental Biology, Signaling by Receptor Tyrosine Kinases, Platelet activation, signaling and aggregation, Signaling by GPCR

Orthologs