PANTHER Gene Information   
Gene Symbol(s): BRIP1
Organism: Bos taurus
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Gene Name: BRCA1 interacting helicase 1
Gene ID: ENSBTAG00000012068.7
Protein ID: F1MMS0
Persistent Id: PTN000158328
Alternate Ids:
F1MMS0_BOVIN(UniProtKB-ID) ENSBTAP00000053187(Ensembl_PRO)
F1MMS0(Synonym) ENSBTAT00000061499(Ensembl_TRS)
ENSBTAG00000012068(Ensembl)
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PANTHER Classification
PANTHER Family: DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER (PTHR11472)
PANTHER Subfamily: FANCONI ANEMIA GROUP J PROTEIN (PTHR11472:SF47)  
PANTHER GO-slim Molecular Function: DNA helicase activity
PANTHER GO-slim Biological Process: double-strand break repair
nucleotide-excision repair
reciprocal meiotic recombination
PANTHER GO-slim Cellular Component: nucleus
PANTHER protein class: DNA helicase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: DNA binding, ATP binding, DNA helicase activity, metal ion binding, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, iron-sulfur cluster binding, isomerase activity, 5'-3' DNA helicase activity
GO BP Complete: chiasma assembly, spermatid development, G-quadruplex DNA unwinding, seminiferous tubule development, meiotic DNA double-strand break processing involved in reciprocal meiotic recombination, DNA duplex unwinding, spermatogonial cell division, nucleotide-excision repair, protein-DNA covalent cross-linking repair, regulation of transcription by RNA polymerase II, double-strand break repair involved in meiotic recombination
GO CC Complete: replication fork, nucleus, nuclear membrane, cytoplasm, BRCA1-B complex, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: DNA Double-Strand Break Repair, Generic Transcription Pathway, Resolution of D-loop Structures through Holliday Junction Intermediates, Homologous DNA Pairing and Strand Exchange, HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA), Resolution of D-Loop Structures, Gene expression (Transcription), Presynaptic phase of homologous DNA pairing and strand exchange, Homology Directed Repair, Processing of DNA double-strand break ends, Regulation of TP53 Activity through Phosphorylation, RNA Polymerase II Transcription, G2/M DNA damage checkpoint, Cell Cycle, Regulation of TP53 Activity, DNA Repair, HDR through Single Strand Annealing (SSA), Transcriptional Regulation by TP53, HDR through Homologous Recombination (HRR), G2/M Checkpoints, Cell Cycle Checkpoints

Orthologs