PANTHER Gene Information   
Gene Symbol(s): EP300
Organism: Macaca mulatta
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Gene Name: histone acetyltransferase
Gene ID: ENSMMUG00000000893.4
Protein ID: A0A5F8AFL2
Persistent Id: PTN000351811
Alternate Ids:
ENSMMUG00000000893(Ensembl) ENSMMUP00000076664(Ensembl_PRO)
AFE77084(EMBL-CDS) JU333329(EMBL)
NP_001253415(refSeq) 380810418(GI)
ENSMMUT00000080799(Ensembl_TRS) A0A5F8AFL2(Synonym)
706258(GeneID) A0A5F8AFL2_MACMU(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: CBP/P300-RELATED (PTHR13808)
PANTHER Subfamily: HISTONE ACETYLTRANSFERASE P300 (PTHR13808:SF29)  
PANTHER GO-slim Molecular Function: chromatin DNA binding
transcription coactivator activity
histone acetyltransferase activity
PANTHER GO-slim Biological Process: positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: histone acetyltransferase complex
transcription regulator complex
PANTHER protein class: histone modifying enzyme
Pathway Categories: Gonadotropin-releasing hormone receptor pathway
   p300
TGF-beta signaling pathway
   Co-activators or corepressors
Huntington disease
   CREB binding protein
Wnt signaling pathway
   CREB binding protein
p53 pathway
   P300
p53 pathway
   CREB binding protein
Transcription regulation by bZIP transcription factor
   CBP/P300
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   cAMP response element binding protein
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: nuclear receptor binding, acetyltransferase activity, histone H4K16 acetyltransferase activity, peptide-lysine-N-acetyltransferase activity, transcription coactivator binding, p53 binding, histone H3K14 acetyltransferase activity, acetylation-dependent protein binding, histone H2AK5 acetyltransferase activity, zinc ion binding, histone lactyltransferase (CoA-dependent) activity, histone H3K9 acetyltransferase activity, histone H3K23 acetyltransferase activity, histone H3K18 acetyltransferase activity, histone H4K8 acetyltransferase activity, histone H4K5 acetyltransferase activity, protein propionyltransferase activity, histone H3K122 acetyltransferase activity, histone H4K12 acetyltransferase activity, NF-kappaB binding, lysine N-acetyltransferase activity, acting on acetyl phosphate as donor, nuclear androgen receptor binding, metal ion binding, histone H2AK9 acetyltransferase activity, histone butyryltransferase activity, peptide butyryltransferase activity, histone crotonyltransferase activity, histone H3 acetyltransferase activity, acyltransferase activity, histone H2BK5 acetyltransferase activity, histone H2B acetyltransferase activity, histone H3K4 acetyltransferase activity, histone H2BK12 acetyltransferase activity, histone H3K36 acetyltransferase activity, histone H3K27 acetyltransferase activity, DNA-binding transcription factor binding, chromatin DNA binding, chromatin binding, beta-catenin binding, damaged DNA binding, transcription coregulator binding, DNA binding, histone acetyltransferase activity, pre-mRNA intronic binding, transcription coregulator activity, transcription coactivator activity, RNA polymerase II-specific DNA-binding transcription factor binding, STAT family protein binding, transferase activity, histone H3K56 acetyltransferase activity, histone H4 acetyltransferase activity
GO BP Complete: response to estrogen, transcription by RNA polymerase II, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, negative regulation of gluconeogenesis, fat cell differentiation, face morphogenesis, regulation of androgen receptor signaling pathway, learning or memory, response to hypoxia, positive regulation of DNA-templated transcription, apoptotic process, platelet formation, positive regulation of neuron projection development, positive regulation of protein import into nucleus, positive regulation of TORC1 signaling, transcription initiation-coupled chromatin remodeling, B cell differentiation, circadian rhythm, animal organ morphogenesis, positive regulation of receptor signaling pathway via JAK-STAT, cellular response to nutrient levels, somitogenesis, negative regulation of autophagy, positive regulation of gene expression, behavioral defense response, regulation of mitochondrion organization, multicellular organism growth, positive regulation by host of viral transcription, positive regulation of transcription by RNA polymerase II, negative regulation of transcription by RNA polymerase II, heart development, chromatin remodeling, cellular response to L-leucine, thigmotaxis, cellular response to UV, megakaryocyte development, negative regulation of protein-containing complex assembly, positive regulation of T-helper 17 cell lineage commitment, lung development, swimming, regulation of tubulin deacetylation, regulation of DNA-templated transcription, regulation of glycolytic process, canonical NF-kappaB signal transduction, regulation of transcription by RNA polymerase II, protein destabilization, rhythmic process, skeletal muscle tissue development, protein stabilization, positive regulation of transforming growth factor beta receptor signaling pathway
GO CC Complete: nucleus, transcription regulator complex, cytoplasm, cytosol, protein-containing complex, chromatin, histone acetyltransferase complex, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: -

Orthologs