PANTHER Gene Information   
Gene Symbol(s): CREBBP
Organism: Canis lupus familiaris
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Gene Name: histone acetyltransferase
Gene ID: ENSCAFG00845001617.1
Protein ID: A0A8I3MJJ8
Persistent Id: PTN000351850
Alternate Ids:
A0A8I3MJJ8_CANLF(UniProtKB-ID) ENSCAFG00845001617(Ensembl)
A0A8I3MJJ8(Synonym) ENSCAFP00845002277(Ensembl_PRO)
ENSCAFT00845002858(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: CBP/P300-RELATED (PTHR13808)
PANTHER Subfamily: CREB-BINDING PROTEIN (PTHR13808:SF34)  
PANTHER GO-slim Molecular Function: chromatin DNA binding
transcription coactivator activity
histone acetyltransferase activity
PANTHER GO-slim Biological Process: positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: histone acetyltransferase complex
transcription regulator complex
PANTHER protein class: histone modifying enzyme
Pathway Categories: TGF-beta signaling pathway
   Co-activators or corepressors
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   CREB binding protein
Huntington disease
   CREB binding protein
Wnt signaling pathway
   CREB binding protein
Hedgehog signaling pathway
   CREB binding protein
Hypoxia response via HIF activation
   p300
p53 pathway
   CREB binding protein
Transcription regulation by bZIP transcription factor
   CBP/P300
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   cAMP response element binding protein
Gonadotropin-releasing hormone receptor pathway
   CBP

GO MF Complete: chromatin DNA binding, zinc ion binding, peptide lactyltransferase (CoA-dependent) activity, chromatin binding, histone H3K18 acetyltransferase activity, damaged DNA binding, histone H3K27 acetyltransferase activity, MRF binding, transcription coactivator binding, histone acetyltransferase activity, p53 binding, transcription coactivator activity, RNA polymerase II-specific DNA-binding transcription factor binding, transcription corepressor activity
GO BP Complete: negative regulation of transcription by RNA polymerase II, protein destabilization, positive regulation of protein localization to nucleus, chromatin remodeling, cellular response to nutrient levels, rhythmic process, positive regulation of double-strand break repair via homologous recombination, cellular response to UV, canonical NF-kappaB signal transduction, positive regulation of transcription by RNA polymerase II, negative regulation of transcription by RNA polymerase I, positive regulation of transforming growth factor beta receptor signaling pathway
GO CC Complete: transcription regulator complex, nuclear body, cytoplasm, histone acetyltransferase complex
Reactome Pathways: RUNX1 regulates transcription of genes involved in differentiation of myeloid cells, Cellular response to heat stress, Signaling by Nuclear Receptors, HSF1-dependent transactivation, Signaling by WNT, Cellular response to chemical stress, Immune System, Formation of the beta-catenin:TCF transactivating complex, LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production, Cytoprotection by HMOX1, CD209 (DC-SIGN) signaling, Estrogen-dependent gene expression, Regulation of FOXO transcriptional activity by acetylation, TCF dependent signaling in response to WNT, ESR-mediated signaling, Gene expression (Transcription), Activation of the TFAP2 (AP-2) family of transcription factors, Cellular response to hypoxia, Generic Transcription Pathway, Transcriptional regulation by RUNX1, Attenuation phase, Regulation of gene expression by Hypoxia-inducible Factor, FOXO-mediated transcription, Regulation of lipid metabolism by PPARalpha, Transcriptional regulation by RUNX3, Metabolism of lipids, Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors, Innate Immune System, Signal Transduction, Cytosolic sensors of pathogen-associated DNA , KEAP1-NFE2L2 pathway, Cellular responses to stimuli, RNA Polymerase II Transcription, Nuclear events mediated by NFE2L2, Metabolism, C-type lectin receptors (CLRs), RUNX3 regulates NOTCH signaling, Cellular responses to stress