PANTHER Gene Information   
Gene Symbol(s): AKT1
Organism: Gallus gallus
View Gene in Tree
Tree Reduced Tree  
Tree Reduced Tree
Gene Name: RAC-alpha serine_threonine-protein kinase
Gene ID: ENSGALG00010017364.1
Protein ID: A0A8V0Z0D0
Persistent Id: PTN000682383
Alternate Ids:
ENSGALG00010017364(Ensembl) ENSGALP00010024506(Ensembl_PRO)
ENSGALT00010041894(Ensembl_TRS) A0A8V0Z0D0(Synonym)
A0A8V0Z0D0_CHICK(UniProtKB-ID)
Show All

PANTHER Classification
PANTHER Family: SERINE/THREONINE-PROTEIN KINASE (PTHR24356)
PANTHER Subfamily: RAC-ALPHA SERINE_THREONINE-PROTEIN KINASE (PTHR24356:SF171)  
PANTHER GO-slim Molecular Function: protein serine/threonine kinase activity
PANTHER GO-slim Biological Process: peptidyl-serine phosphorylation
intracellular signal transduction
PANTHER GO-slim Cellular Component:
PANTHER protein class: non-receptor serine/threonine protein kinase
Pathway Categories: Interleukin signaling pathway
   Protein kinase B
PI3 kinase pathway
   Protein kinase B
Endothelin signaling pathway
   protein kinase B
T cell activation
   protein kinase B
VEGF signaling pathway
   protein kinase B
Hypoxia response via HIF activation
   protein kinase B
p53 pathway
   protein kinase B
Gonadotropin-releasing hormone receptor pathway
   AKT
p53 pathway feedback loops 2
   protein kinase B
FGF signaling pathway
   protein kinase B
Angiogenesis
   Protein Kinase B
p53 pathway by glucose deprivation
   protein kinase B
Apoptosis signaling pathway
   protein kinase B
Huntington disease
   protein kinase B
Insulin/IGF pathway-protein kinase B signaling cascade
   protein kinase B
EGF receptor signaling pathway
   protein kinase B
FAS signaling pathway
   Apoptosis signal regulating kinase 1
Inflammation mediated by chemokine and cytokine signaling pathway
   protein kinase B
Ras Pathway
   protein kinase B
CCKR signaling map
   AKT1
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: phosphatidylinositol-3,4,5-trisphosphate binding, ATP binding, protein kinase binding, potassium channel activator activity, calmodulin binding, protein serine/threonine/tyrosine kinase activity, protein homodimerization activity, protein serine/threonine kinase activity, nitric-oxide synthase regulator activity, phosphatidylinositol-3,4-bisphosphate binding, protein serine kinase activity, 14-3-3 protein binding
GO BP Complete: response to food, cellular response to decreased oxygen levels, mammalian oogenesis stage, epidermal growth factor receptor signaling pathway, cellular response to nerve growth factor stimulus, positive regulation of fat cell differentiation, cell migration involved in sprouting angiogenesis, glucose metabolic process, sphingosine-1-phosphate receptor signaling pathway, positive regulation of glycogen biosynthetic process, cellular response to prostaglandin E stimulus, negative regulation of cGAS/STING signaling pathway, inflammatory response, positive regulation of cell growth, negative regulation of fatty acid beta-oxidation, peripheral nervous system myelin maintenance, regulation of neuron projection development, negative regulation of protein ubiquitination, negative regulation of intrinsic apoptotic signaling pathway, intracellular signal transduction, positive regulation of protein localization to nucleus, positive regulation of protein localization to endoplasmic reticulum, positive regulation of TORC1 signaling, positive regulation of protein localization to cell surface, positive regulation of organ growth, insulin-like growth factor receptor signaling pathway, negative regulation of PERK-mediated unfolded protein response, activation-induced cell death of T cells, negative regulation of gene expression, cellular response to granulocyte macrophage colony-stimulating factor stimulus, proteasome-mediated ubiquitin-dependent protein catabolic process, protein import into nucleus, negative regulation of autophagy, positive regulation of gene expression, negative regulation of long-chain fatty acid import across plasma membrane, glucose homeostasis, cellular response to epidermal growth factor stimulus, gene expression, lipopolysaccharide-mediated signaling pathway, maintenance of protein location in mitochondrion, establishment of protein localization to mitochondrion, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, negative regulation of lymphocyte migration, protein ubiquitination, positive regulation of nitric oxide biosynthetic process, insulin receptor signaling pathway, negative regulation of cilium assembly, negative regulation of proteolysis, positive regulation of transcription by RNA polymerase II, execution phase of apoptosis, regulation of postsynapse organization, positive regulation of smooth muscle cell proliferation, response to UV-A, response to heat, phosphatidylinositol 3-kinase/protein kinase B signal transduction, regulation of tRNA methylation, apoptotic mitochondrial changes, striated muscle cell differentiation, behavioral response to pain, osteoblast differentiation, cellular response to tumor necrosis factor, response to fluid shear stress, interleukin-18-mediated signaling pathway, cellular response to oxidised low-density lipoprotein particle stimulus, negative regulation of release of cytochrome c from mitochondria, positive regulation of G1/S transition of mitotic cell cycle, positive regulation of protein localization to plasma membrane, negative regulation of protein localization to lysosome, cellular response to peptide, positive regulation of D-glucose import, negative regulation of leukocyte cell-cell adhesion, positive regulation of blood vessel endothelial cell migration, positive regulation of lipid biosynthetic process, glycogen biosynthetic process, positive regulation of sodium ion transport, regulation of myelination, positive regulation of endothelial cell proliferation, cellular response to vascular endothelial growth factor stimulus, positive regulation of fibroblast migration
GO CC Complete: mitochondrial intermembrane space, cell-cell junction, ciliary basal body, spindle, cytosol, vesicle, protein-containing complex, glutamatergic synapse, plasma membrane, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: -

Orthologs