PANTHER Gene Information

Gene Symbol(s):

Adcy1

Organism:

Rattus norvegicus

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Gene Name:

Adenylate cyclase type 1

Gene ID:

1309318

Protein ID:

D4A3N4

Persistent Id:

PTN000229384

Alternate Ids:

NP_001100709(refSeq)	D4A3N4_RAT(UniProtKB-ID)
1309318(RGD)	ENSRNOP00000070999(Ensembl_PRO)
ENSRNOT00000088032(Ensembl_TRS)	CHEMBL2095179(ChEMBL)
ENSRNOG00000059479(Ensembl)	D4A3N4(Synonym)
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PANTHER Classification

PANTHER Family:	ADENYLATE CYCLASE TYPE 1 (PTHR45627)
PANTHER Subfamily:	ADENYLATE CYCLASE TYPE 1 (PTHR45627:SF26)
PANTHER GO-slim Molecular Function:	adenylate cyclase activity
PANTHER GO-slim Biological Process:	purine ribonucleotide biosynthetic process adenylate cyclase-activating G protein-coupled receptor signaling pathway cyclic nucleotide metabolic process
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	adenylate cyclase

Pathway Categories:

Endothelin signaling pathway

Adenylate cyclase

GABA-B receptor II signaling

adenylate cyclase

Gonadotropin-releasing hormone receptor pathway

Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway

Adenylyl cyclase

CCKR signaling map

Adenylate cyclase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	calcium- and calmodulin-responsive adenylate cyclase activity, ATP binding, metal ion binding, adenylate cyclase activity
GO BP Complete:	cAMP biosynthetic process, positive regulation of long-term synaptic potentiation, adenylate cyclase-activating G protein-coupled receptor signaling pathway, response to xenobiotic stimulus, presynaptic modulation of chemical synaptic transmission, neuroinflammatory response, circadian rhythm, regulation of circadian rhythm, long-term memory, axonogenesis, modulation of chemical synaptic transmission, positive regulation of CREB transcription factor activity, intracellular signal transduction
GO CC Complete:	Schaffer collateral - CA1 synapse, nucleus, postsynaptic density, hippocampal mossy fiber to CA3 synapse, presynapse, cytoplasm, glutamatergic synapse, axon hillock, plasma membrane, postsynaptic density membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Orthologs

ID	Organism	Type
HUMAN\|HGNC=232\|UniProtKB=Q08828	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000051596.1\|UniProtKB=H2QUJ4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010304.3\|UniProtKB=G3R473	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000006421.4\|UniProtKB=A0A5F7ZYU0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=99677\|UniProtKB=O88444	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000009520\|UniProtKB=P19754	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000016726.5\|UniProtKB=F1ST77	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000025044.4\|UniProtKB=A0A5F5PP65	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000011140.6\|UniProtKB=A0A5F5XNK3	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845011343.1\|UniProtKB=A0A8I3RWF9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000010195.4\|UniProtKB=A0A5F8GET0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000043203.1\|UniProtKB=A0A6I8NH00	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010008388.1\|UniProtKB=A0A8V0XY43	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000007921.3\|UniProtKB=G1KHB4	Anolis carolinensis	LDO
XENLA\|Gene=adcy1.S\|UniProtKB=A0A8J1L1W1	Xenopus laevis	O
XENLA\|Gene=adcy1.L\|UniProtKB=A0A8J1KZ78	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-950909\|UniProtKB=A0A6I8QGP8	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000012874.2\|UniProtKB=H2MC48	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-070705-302\|UniProtKB=D1MIA2	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000017169.2\|UniProtKB=A0A3B3H4M0	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-100805-1\|UniProtKB=D1MIA3	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000013092.1\|UniProtKB=W5N677	lepisosteus oculatus	LDO
CAEEL\|WormBase=WBGene00000070\|UniProtKB=G5EE33	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG09223\|UniProtKB=A8X8B1	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00090344\|UniProtKB=A0A2A6BQS5	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0003301\|UniProtKB=P32870	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP000727\|UniProtKB=A0A1S4GAE3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC012082\|UniProtKB=A0A139WCA1	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_48469\|UniProtKB=E9GC19	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW003150\|UniProtKB=B7P9V2	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g234384\|UniProtKB=A7RRQ7	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG21914\|UniProtKB=B3RQI4	Trichoplax adhaerens	O
BATDJ\|Gene_ORFName=BATDEDRAFT_23648\|UniProtKB=F4NXY1	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0281545\|UniProtKB=Q03100	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_51614\|UniProtKB=F1A4L3	Dictyostelium purpureum	O
GIAIC\|EnsemblGenome=GL50803_16599\|UniProtKB=A8B947	Giardia intestinalis	O
PARTE\|EnsemblGenome=GSPATT00035944001\|UniProtKB=A0C7P7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028571001\|UniProtKB=A0BG69	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00020771001\|UniProtKB=A0DVQ1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017090001\|UniProtKB=A0DI52	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00008342001\|UniProtKB=A0CM46	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00035991001\|UniProtKB=A0C7U3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00035327001\|UniProtKB=A0C5Y1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000356001\|UniProtKB=A0BBK4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00037686001\|UniProtKB=A0CEN0	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00037840001\|UniProtKB=A0CF34	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028233001\|UniProtKB=A0BF81	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00022215001\|UniProtKB=A0E179	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00008067001\|UniProtKB=A0CL53	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00013081001\|UniProtKB=A0D3H6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00030444001\|UniProtKB=A0BMP1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00008009001\|UniProtKB=A0CKZ5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00035245001\|UniProtKB=A0C5P9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00036203001\|UniProtKB=A0C8F3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019986001\|UniProtKB=A0DTD8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017694001\|UniProtKB=A0DJY3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00021918001\|UniProtKB=A0E0D3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000775001\|UniProtKB=A0CJU6	Paramecium tetraurelia	O
PARTE\|Gene_ORFName=PTMB.171c\|UniProtKB=Q6BG52	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025644001\|UniProtKB=A0EC90	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00005251001\|UniProtKB=A0BPN4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00032566001\|UniProtKB=A0BVZ7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00030881001\|UniProtKB=A0BNX5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025082001\|UniProtKB=A0EAN1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029118001\|UniProtKB=A0BHR5	Paramecium tetraurelia	O