PANTHER Gene Information   
Gene Symbol(s): Dcp1a
Organism: Rattus norvegicus
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Gene Name: 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase
Gene ID: 1561298
Protein ID: D4AE80
Persistent Id: PTN000418301
Alternate Ids:
NP_001178760(refSeq) 300797332(GI)
D4AE80_RAT(UniProtKB-ID) ENSRNOG00000016015(Ensembl)
ENSRNOP00000021473(Ensembl_PRO) 361109(GeneID)
ENSRNOT00000021475(Ensembl_TRS) 1561298(RGD)
D4AE80(Synonym)
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PANTHER Classification
PANTHER Family: TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1 (PTHR16290)
PANTHER Subfamily: MRNA-DECAPPING ENZYME 1A (PTHR16290:SF4)  
PANTHER GO-slim Molecular Function: mRNA binding
PANTHER GO-slim Biological Process: nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
RNA decapping
PANTHER GO-slim Cellular Component: P-body
PANTHER protein class: mRNA capping factor
Pathway Categories: TGF-beta signaling pathway
   Co-activators or corepressors
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: identical protein binding, kinesin binding, mRNA binding, enzyme activator activity
GO BP Complete: mRNA methylguanosine-cap decapping, protein localization to cytoplasmic stress granule, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, deadenylation-independent decapping of nuclear-transcribed mRNA, deadenylation-dependent decapping of nuclear-transcribed mRNA
GO CC Complete: dendrite, cytoplasmic ribonucleoprotein granule, cytoplasm, P-body
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA, Deadenylation-dependent mRNA decay, Regulation of mRNA stability by proteins that bind AU-rich elements, Metabolism of RNA, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC), mRNA decay by 5' to 3' exoribonuclease, Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA, Nonsense-Mediated Decay (NMD)

Orthologs