PANTHER Gene Information   
Gene Symbol(s): SIAH2
Organism: Gallus gallus
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Gene Name: E3 ubiquitin-protein ligase
Gene ID: ENSGALG00010001127.1
Protein ID: E1C3Q9
Persistent Id: PTN000034830
Alternate Ids:
E1C3Q9(Synonym) ENSGALG00010001127(Ensembl)
118095381(GI) XP_426719(refSeq)
429164(GeneID) E1C3Q9_CHICK(UniProtKB-ID)
ENSGALT00010002561(Ensembl_TRS) ENSGALP00010001111(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: E3 UBIQUITIN-PROTEIN LIGASE SIAH2 (PTHR45877)
PANTHER Subfamily: E3 UBIQUITIN-PROTEIN LIGASE SIAH2 (PTHR45877:SF4)  
PANTHER GO-slim Molecular Function: ubiquitin protein ligase activity
ubiquitin-like protein conjugating enzyme binding
PANTHER GO-slim Biological Process: proteasome-mediated ubiquitin-dependent protein catabolic process
PANTHER GO-slim Cellular Component: cytoplasm
PANTHER protein class: ubiquitin-protein ligase
Pathway Categories: Wnt signaling pathway
   Seven in absentia homolog 1
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: zinc ion binding, ubiquitin conjugating enzyme binding, ubiquitin protein ligase activity
GO BP Complete: negative regulation of canonical Wnt signaling pathway, proteasome-mediated ubiquitin-dependent protein catabolic process, rhythmic process, canonical Wnt signaling pathway, negative regulation of extrinsic apoptotic signaling pathway, regulation of circadian rhythm
GO CC Complete: cytoplasm, cytosol, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Deubiquitination, Ub-specific processing proteases, Post-translational protein modification, Metabolism of proteins, Adaptive Immune System, Class I MHC mediated antigen processing & presentation, Immune System, Antigen processing: Ubiquitination & Proteasome degradation

Orthologs