PANTHER Gene Information   
Gene Symbol(s): CREBBP
Organism: Bos taurus
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Gene Name: histone acetyltransferase
Gene ID: ENSBTAG00000026403.5
Protein ID: F1MD32
Persistent Id: PTN000351849
Alternate Ids:
505453(GeneID) ENSBTAP00000005092(Ensembl_PRO)
F1MD32(Synonym) ENSBTAT00000005092(Ensembl_TRS)
255683523(GI) ENSBTAG00000026403(Ensembl)
F1MD32_BOVIN(UniProtKB-ID) NM_001164022(refSeq)
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PANTHER Classification
PANTHER Family: CBP/P300-RELATED (PTHR13808)
PANTHER Subfamily: CREB-BINDING PROTEIN (PTHR13808:SF34)  
PANTHER GO-slim Molecular Function: chromatin DNA binding
transcription coactivator activity
histone acetyltransferase activity
PANTHER GO-slim Biological Process: positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: histone acetyltransferase complex
transcription regulator complex
PANTHER protein class: histone modifying enzyme
Pathway Categories: TGF-beta signaling pathway
   Co-activators or corepressors
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   CREB binding protein
Huntington disease
   CREB binding protein
Wnt signaling pathway
   CREB binding protein
Hedgehog signaling pathway
   CREB binding protein
Hypoxia response via HIF activation
   p300
p53 pathway
   CREB binding protein
Transcription regulation by bZIP transcription factor
   CBP/P300
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   cAMP response element binding protein
Gonadotropin-releasing hormone receptor pathway
   CBP

GO MF Complete: histone H2BK5 acetyltransferase activity, histone H3K4 acetyltransferase activity, histone H4K16 acetyltransferase activity, histone H2BK12 acetyltransferase activity, histone H3K36 acetyltransferase activity, histone H3K27 acetyltransferase activity, MRF binding, transcription coactivator binding, p53 binding, histone H3K14 acetyltransferase activity, chromatin DNA binding, histone H2AK5 acetyltransferase activity, zinc ion binding, peptide lactyltransferase (CoA-dependent) activity, histone H3K9 acetyltransferase activity, histone H3K23 acetyltransferase activity, histone H3K18 acetyltransferase activity, histone H4K8 acetyltransferase activity, damaged DNA binding, histone H4K5 acetyltransferase activity, histone H3K122 acetyltransferase activity, histone H4K12 acetyltransferase activity, histone acetyltransferase activity, transcription coactivator activity, RNA polymerase II-specific DNA-binding transcription factor binding, transcription corepressor activity, histone H2AK9 acetyltransferase activity, histone H3K56 acetyltransferase activity
GO BP Complete: negative regulation of transcription by RNA polymerase II, protein destabilization, positive regulation of protein localization to nucleus, chromatin remodeling, cellular response to nutrient levels, rhythmic process, positive regulation of double-strand break repair via homologous recombination, cellular response to UV, canonical NF-kappaB signal transduction, positive regulation of transcription by RNA polymerase II, negative regulation of transcription by RNA polymerase I, positive regulation of transforming growth factor beta receptor signaling pathway
GO CC Complete: transcription regulator complex, nuclear body, cytoplasm, histone acetyltransferase complex
Reactome Pathways: CD209 (DC-SIGN) signaling, Gene expression (Transcription), HSF1-dependent transactivation, LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production, Cellular response to chemical stress, Cytoprotection by HMOX1, RUNX3 regulates NOTCH signaling, Signal Transduction, Metabolism, Innate Immune System, Notch-HLH transcription pathway, Activation of the TFAP2 (AP-2) family of transcription factors, RUNX1 regulates transcription of genes involved in differentiation of myeloid cells, Attenuation phase, Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors, Signaling by Nuclear Receptors, Generic Transcription Pathway, Cytosolic sensors of pathogen-associated DNA , Cellular responses to stimuli, Regulation of lipid metabolism by PPARalpha, TCF dependent signaling in response to WNT, Nuclear events mediated by NFE2L2, Estrogen-dependent gene expression, KEAP1-NFE2L2 pathway, C-type lectin receptors (CLRs), Immune System, Regulation of FOXO transcriptional activity by acetylation, RNA Polymerase II Transcription, Metabolism of lipids, Formation of the beta-catenin:TCF transactivating complex, Cellular responses to stress, ESR-mediated signaling, Cellular response to hypoxia, Transcriptional regulation by RUNX1, DDX58/IFIH1-mediated induction of interferon-alpha/beta, Regulation of gene expression by Hypoxia-inducible Factor, Cellular response to heat stress, Signaling by WNT, FOXO-mediated transcription, TRAF6 mediated IRF7 activation, Transcriptional regulation by RUNX3