PANTHER Gene Information   
Gene Symbol(s): SKI
Organism: Bos taurus
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Gene Name: Ski oncogene
Gene ID: ENSBTAG00000038716.4
Protein ID: F1N727
Persistent Id: PTN000000404
Alternate Ids:
F1N727_BOVIN(UniProtKB-ID) ENSBTAT00000060953(Ensembl_TRS)
ENSBTAG00000038716(Ensembl) F1N727(Synonym)
ENSBTAP00000053695(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: SKI ONCOGENE-RELATED (PTHR10005)
PANTHER Subfamily: SKI ONCOGENE (PTHR10005:SF15)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
SMAD binding
DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process: negative regulation of BMP signaling pathway
negative regulation of transcription by RNA polymerase II
regulation of transforming growth factor beta receptor signaling pathway
PANTHER GO-slim Cellular Component: nucleus
cytoplasm
transcription regulator complex
PANTHER protein class:
Pathway Categories: TGF-beta signaling pathway
   Co-activators or corepressors
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein kinase binding, zinc ion binding, protein domain specific binding, identical protein binding, ubiquitin protein ligase binding, SMAD binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, DNA-binding transcription factor binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete: negative regulation of transcription by RNA polymerase II, negative regulation of BMP signaling pathway, negative regulation of Schwann cell proliferation, negative regulation of SMAD protein signal transduction, negative regulation of activin receptor signaling pathway, myotube differentiation, negative regulation of transforming growth factor beta receptor signaling pathway, negative regulation of osteoblast differentiation
GO CC Complete: nucleus, transcription regulator complex, centrosome, PML body, cytoplasm, protein-containing complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Generic Transcription Pathway, Gene expression (Transcription), Signaling by TGF-beta Receptor Complex, Downregulation of SMAD2/3:SMAD4 transcriptional activity, Signaling by BMP, Signaling by TGFB family members, Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer, RNA Polymerase II Transcription, Signal Transduction

Orthologs