PANTHER Gene Information   
Gene Symbol(s): SKIL
Organism: Gallus gallus
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Gene Name: SKI like proto-onco
Gene ID: ENSGALG00010016675.1
Protein ID: F1P0N0
Persistent Id: PTN000000380
Alternate Ids:
F1P0N0(Synonym) ENSGALG00010016675(Ensembl)
F1P0N0_CHICK(UniProtKB-ID) ENSGALT00010040198(Ensembl_TRS)
ENSGALP00010023306(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: SKI ONCOGENE-RELATED (PTHR10005)
PANTHER Subfamily: SKI-LIKE PROTEIN (PTHR10005:SF3)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
SMAD binding
DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process: negative regulation of BMP signaling pathway
negative regulation of transcription by RNA polymerase II
regulation of transforming growth factor beta receptor signaling pathway
PANTHER GO-slim Cellular Component: nucleus
cytoplasm
transcription regulator complex
PANTHER protein class:
Pathway Categories: TGF-beta signaling pathway
   Co-activators or corepressors
Gonadotropin-releasing hormone receptor pathway
   SKIL
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein domain specific binding, protein homodimerization activity, SMAD binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, sequence-specific DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, chromatin binding, DNA-binding transcription factor binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete: positive regulation of extrinsic apoptotic signaling pathway via death domain receptors, positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage, lymphocyte homeostasis, transforming growth factor beta receptor signaling pathway, intrinsic apoptotic signaling pathway in response to DNA damage, extrinsic apoptotic signaling pathway via death domain receptors, negative regulation of transcription by RNA polymerase II, negative regulation of BMP signaling pathway, negative regulation of DNA-templated transcription, negative regulation of cell differentiation, regulation of cell cycle, lens fiber cell differentiation, negative regulation of transforming growth factor beta receptor signaling pathway
GO CC Complete: nucleus, transcription regulator complex, cytoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: RNA Polymerase II Transcription, Gene expression (Transcription), Signaling by TGFB family members, Signaling by TGF-beta Receptor Complex, Downregulation of SMAD2/3:SMAD4 transcriptional activity, Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer, Signal Transduction, Generic Transcription Pathway

Orthologs