PANTHER Gene Information

Gene Symbol(s):

ALDH5A1

Organism:

Macaca mulatta

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Tree

Gene Name:

Succinate-semialdehyde dehydrogenase

Gene ID:

ENSMMUG00000019368.4

Protein ID:

F6T9P8

Persistent Id:

PTN000192596

Alternate Ids:

F6T9P8(Synonym)	109069782(GI)
XM_001101142(refSeq)	ENSMMUG00000019368(Ensembl)
F6T9P8_MACMU(UniProtKB-ID)	707902(GeneID)
ENSMMUT00000027200(Ensembl_TRS)	ENSMMUP00000025444(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL (PTHR43353)
PANTHER Subfamily:	SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL (PTHR43353:SF5)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	nitrogen compound metabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	dehydrogenase

Pathway Categories:

5-Hydroxytryptamine degredation

Aldehyde Dehydrogenase

Aminobutyrate degradation

Succinate semialdehyde dehydrogenase

Gamma-aminobutyric acid synthesis

Succinate semialdehyde dehydrogenase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	succinate-semialdehyde dehydrogenase (NAD+) activity, identical protein binding, succinate-semialdehyde dehydrogenase [NAD(P)+] activity, oxidoreductase activity
GO BP Complete:	glutamate metabolic process, central nervous system development, gamma-aminobutyric acid catabolic process, post-embryonic development, succinate metabolic process, synaptic transmission, GABAergic, gamma-aminobutyric acid metabolic process
GO CC Complete:	mitochondrion, synapse

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=408\|UniProtKB=P51649	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000017776.7\|UniProtKB=A0A2I3S135	Pan troglodytes	LDO
PANTR\|Gene=ALDH5A1\|UniProtKB=Q6A2H0	Pan troglodytes	LDO
GORGO\|Gene=ALDH5A1\|UniProtKB=Q6A2H1	Gorilla gorilla gorilla	LDO
GORGO\|Ensembl=ENSGGOG00000006634.3\|UniProtKB=G3QUT4	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=2441982\|UniProtKB=Q8BWF0	Mus musculus	LDO
RAT\|RGD=621422\|UniProtKB=P51650	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000021902.6\|UniProtKB=E1BDP3	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000001090.5\|UniProtKB=F1RUE3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000020590.4\|UniProtKB=A0A9L0SUE2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000023906.4\|UniProtKB=M3X6J9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845018965.1\|UniProtKB=A0A8I3P411	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000043455.1\|UniProtKB=A0A5F8H444	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000043474.1\|UniProtKB=A0A6I8PGP9	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010008001.1\|UniProtKB=A0A1D5PFY7	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000002616.4\|UniProtKB=G1KB06	Anolis carolinensis	LDO
XENLA\|Gene=aldh5a1.L\|UniProtKB=A0A1L8FY56	Xenopus laevis	O
XENLA\|Gene=aldh5a1.S\|UniProtKB=A0A8J0VM74	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1013005\|UniProtKB=B4F708	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000020358.2\|UniProtKB=H2N1D4	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-070228-2\|UniProtKB=A0A0R4IIB7	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005880.1\|UniProtKB=W5MFE6	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000009379.3\|UniProtKB=F6WXA3	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000009381.3\|UniProtKB=F6WBI7	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118412347\|UniProtKB=A0A9J7KWU4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC115919140\|UniProtKB=A0A7M7MWZ5	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC115929154\|UniProtKB=A0A7M7PPM4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC584281\|UniProtKB=A0A7M7PRG9	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00000113\|UniProtKB=O02266	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00039697\|UniProtKB=A8XYK9	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00100809\|UniProtKB=A0A2A6D3T3	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0039349\|UniProtKB=Q9VBP6	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP003165\|UniProtKB=Q7QBI1	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC011254\|UniProtKB=D6X3H7	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_236060\|UniProtKB=E9FZV2	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW007437\|UniProtKB=B7PUD3	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG95271\|UniProtKB=T1G953	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g150665\|UniProtKB=A7T8X3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g162370\|UniProtKB=A7RT61	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG63836\|UniProtKB=B3RUT6	Trichoplax adhaerens	LDO
TRIAD\|EnsemblGenome=TriadG24320\|UniProtKB=B3RUT5	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_18571\|UniProtKB=A9UWD3	Monosiga brevicollis	LDO
CANAL\|CGD=CAL0000201739\|UniProtKB=Q5AI07	Candida albicans	O
EMENI\|EnsemblGenome=ANIA_01541\|UniProtKB=Q5BD39	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_8G05520\|UniProtKB=Q4WC68	Neosartorya fumigata	O
SCLS1\|EnsemblGenome=SS1G_01166\|UniProtKB=A7E789	Sclerotinia sclerotiorum	O
EMENI\|EnsemblGenome=ANIA_04050\|UniProtKB=Q5B5Y0	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_4G01550\|UniProtKB=Q4W9H6	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_1G03620\|UniProtKB=Q4WK58	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02056\|UniProtKB=Q7SDE2	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_06035\|UniProtKB=A7EL38	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_01423\|UniProtKB=Q0V3J1	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_09804\|UniProtKB=Q0UEL0	Phaeosphaeria nodorum	O
CRYNJ\|EnsemblGenome=CNG03080\|UniProtKB=Q5KDR2	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_04046\|UniProtKB=A0A0D1DZP9	Ustilago maydis	O
YEAST\|SGD=S000000210\|UniProtKB=P38067	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AER007W\|UniProtKB=Q757K5	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000178220\|UniProtKB=Q5AEC3	Candida albicans	LDO
CANAL\|CGD=CAL0000192412\|UniProtKB=Q59T88	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F26191g\|UniProtKB=Q6C0B4	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_01585\|UniProtKB=Q5BCZ5	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_04820\|UniProtKB=Q5B3R0	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G07150\|UniProtKB=Q4WWV0	Neosartorya fumigata	O
SCLS1\|Gene_ORFName=SS1G_06865\|UniProtKB=A7ENG6	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_05209\|UniProtKB=Q0USQ5	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_10011\|UniProtKB=C8VQZ9	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G00110\|UniProtKB=Q4WG33	Neosartorya fumigata	O
EMENI\|EnsemblGenome=ANIA_07315\|UniProtKB=Q5AWL5	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_03829\|UniProtKB=C8V6Q8	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_4G08170\|UniProtKB=Q4WP63	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU00936\|UniProtKB=V5IQD0	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_02611\|UniProtKB=A7EBC5	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_00899\|UniProtKB=Q0V515	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC139.05\|UniProtKB=Q9UTM8	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_00674\|UniProtKB=B6JWA1	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPAC1002.12c\|UniProtKB=Q9US47	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03293\|UniProtKB=B6K3V2	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNI00900\|UniProtKB=Q5KBZ0	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_05610\|UniProtKB=A0A0D1BXH3	Ustilago maydis	LDO
CRYNJ\|EnsemblGenome=CND01570\|UniProtKB=Q5KIV9	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_10846\|UniProtKB=A0A0D1BZT3	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_05600\|UniProtKB=A0A0D1BXG5	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_17645\|UniProtKB=E3L4W6	Puccinia graminis	O
LEIMA\|EnsemblGenome=LMJF_36_1760\|UniProtKB=Q4Q1P8	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb10.70.0630\|UniProtKB=Q38AY7	Trypanosoma brucei	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_268262\|UniProtKB=B8BUC3	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G616_PHYRM\|UniProtKB=H3G616	Phytophthora ramorum	O
PHYRM\|Gene=H3GA49_PHYRM\|UniProtKB=H3GA49	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_08g381702v5\|UniProtKB=A0A2K3DI27	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00004p00210450\|UniProtKB=W1NF04	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_142G00170\|UniProtKB=A0A0K9PXE6	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma05_g29200\|UniProtKB=A0A804J9U0	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_016884mg\|UniProtKB=K3YRJ0	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G058600\|UniProtKB=A0A194YMX1	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb233300\|UniProtKB=A0A804PFC8	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb207050\|UniProtKB=B4FYG3	Zea mays	LDO
ORYSJ\|Gene_OrderedLocusName=LOC_Os02g07760\|UniProtKB=B9F3B6	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g05490v3\|UniProtKB=I1HXS5	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0570900\|UniProtKB=M0XSP9	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6B02G183600\|UniProtKB=A0A3B6PJL2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G155500\|UniProtKB=A0A3B6NLV6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G145400\|UniProtKB=A0A3B6QCZ1	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_003805\|UniProtKB=A0A1U8AKX3	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110803266\|UniProtKB=A0A9R0JAY1	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr11g0484171\|UniProtKB=A0A251TBH2	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr06g0271181\|UniProtKB=A0A251UAZ0	Helianthus annuus	O
HELAN\|Gene_ORFName=HannXRQ_Chr07g0190721\|UniProtKB=A0A251UA64	Helianthus annuus	O
HELAN\|Gene_ORFName=HannXRQ_Chr11g0335861\|UniProtKB=A0A251T9U8	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr06g0271251\|UniProtKB=A0A9K3IVI9	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr13g0608301\|UniProtKB=A0A251SWH7	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C700385530\|UniProtKB=A0A9R1X4Z0	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a004331mg\|UniProtKB=A0A022QM88	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_07749\|UniProtKB=A0A2G2ZUK2	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400017144\|UniProtKB=M1BFP9	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc09g090700.1\|UniProtKB=B1Q3F8	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107792837\|UniProtKB=A0A1S4A1R0	Nicotiana tabacum	O
TOBAC\|Gene=LOC107830185\|UniProtKB=A0A1S4DIN9	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_19s0085g00860\|UniProtKB=F6H9T7	Vitis vinifera	O
VITVI\|Gene_OrderedLocusName=VIT_19s0085g00870\|UniProtKB=D7T119	Vitis vinifera	O
VITVI\|EnsemblGenome=Vitvi19g01741\|UniProtKB=F6H9T6	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_F04474\|UniProtKB=A0A059BYY4	Eucalyptus grandis	LDO
BRACM\|EnsemblGenome=Bra035119\|UniProtKB=A0A397YST0	Brassica campestris	LDO
ARATH\|TAIR=locus=2206405\|UniProtKB=Q9SAK4	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107917888\|UniProtKB=A0A1U8KP45	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107922277\|UniProtKB=A0A1U8KZ95	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_033675\|UniProtKB=A0A061FBA3	Theobroma cacao	LDO
POPTR\|EnsemblGenome=POPTR_010G174000v3\|UniProtKB=B9HYB6	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_16G048100\|UniProtKB=A0A251IYP4	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0605750\|UniProtKB=B9SUZ1	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_08G163700\|UniProtKB=I1KTW3	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_15G263500\|UniProtKB=A0A0R4J5H1	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_2g067660\|UniProtKB=A0A072VAA5	Medicago truncatula	LDO
JUGRE\|Gene=LOC108983566\|UniProtKB=A0A6P9EEQ1	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_6G135470\|UniProtKB=A0A0A0KGA1	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_4G128100\|UniProtKB=A0A251PJS2	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_94736\|UniProtKB=D8RJV5	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_230009\|UniProtKB=D8QTT0	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c6_27580\|UniProtKB=A9TPC4	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c26_10950\|UniProtKB=A0A2K1ICJ7	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0091s0004\|UniProtKB=A0A2R6WGZ8	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_007220010\|UniProtKB=A0A1Y1ILN7	Klebsormidium nitens	LDO