PANTHER Gene Information

Gene Symbol(s):

SKIL

Organism:

Pan troglodytes

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Gene Name:

SKI like proto-onco

Gene ID:

ENSPTRG00000015616.5

Protein ID:

H2QNQ5

Persistent Id:

PTN000000370

Alternate Ids:

ENSPTRT00000029117(Ensembl_TRS)	H2QNQ5_PANTR(UniProtKB-ID)
460844(GeneID)	ENSPTRP00000070313(Ensembl_PRO)
ENSPTRG00000015616(Ensembl)	XP_001163447(refSeq)
JAA42489(EMBL-CDS)	1034160564(GI)
H2QNQ5(Synonym)	GABC01006643(EMBL)
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PANTHER Classification

PANTHER Family:	SKI ONCOGENE-RELATED (PTHR10005)
PANTHER Subfamily:	SKI-LIKE PROTEIN (PTHR10005:SF3)
PANTHER GO-slim Molecular Function:	RNA polymerase II cis-regulatory region sequence-specific DNA binding SMAD binding DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process:	negative regulation of BMP signaling pathway negative regulation of transcription by RNA polymerase II regulation of transforming growth factor beta receptor signaling pathway
PANTHER GO-slim Cellular Component:	nucleus cytoplasm transcription regulator complex
PANTHER protein class:

Pathway Categories:

TGF-beta signaling pathway

Co-activators or corepressors

Gonadotropin-releasing hormone receptor pathway

SKIL

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	SMAD binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, chromatin binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors, positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage, lymphocyte homeostasis, transforming growth factor beta receptor signaling pathway, intrinsic apoptotic signaling pathway in response to DNA damage, extrinsic apoptotic signaling pathway via death domain receptors, negative regulation of transcription by RNA polymerase II, negative regulation of BMP signaling pathway, negative regulation of cell differentiation, blastocyst formation, cell differentiation, regulation of cell cycle, lens fiber cell differentiation, negative regulation of transforming growth factor beta receptor signaling pathway
GO CC Complete:	nucleus, transcription regulator complex, cytoplasm, protein-containing complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=10897\|UniProtKB=P12757	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000026891.2\|UniProtKB=G3RYD2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000039099.2\|UniProtKB=G7MJB2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=106203\|UniProtKB=Q60665	Mus musculus	LDO
RAT\|RGD=621399\|UniProtKB=D3ZWL1	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000004154.4\|UniProtKB=E1BJ37	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000011746.5\|UniProtKB=F1SH27	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000010663.4\|UniProtKB=A0A9L0S6H7	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000031064.4\|UniProtKB=A0A2I2UY81	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845022824.1\|UniProtKB=A0A8I3PJY2	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000000724.3\|UniProtKB=F6ZDC3	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010016675.1\|UniProtKB=F1P0N0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000016018.4\|UniProtKB=G1KRY8	Anolis carolinensis	LDO
XENLA\|Gene=skil.S\|UniProtKB=A0A8J1KU38	Xenopus laevis	O
XENLA\|Gene=skil.L\|UniProtKB=A0A1L8GA38	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-486095\|UniProtKB=F7DVM3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000023373.1\|UniProtKB=A0A3B3I8Q8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-080723-40\|UniProtKB=B3DGU8	Danio rerio	O
DANRE\|Gene=skila\|UniProtKB=A0A8M6YU52	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007221.1\|UniProtKB=W5MK33	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000000087.3\|UniProtKB=F6TS32	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118429858\|UniProtKB=A0A9J7N7S3	Branchiostoma floridae	LDO
PRIPA\|EnsemblGenome=WBGene00111802\|UniProtKB=A0A2A6B5M9	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0085450\|UniProtKB=Q00G30	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP029919\|UniProtKB=A0A903XX60	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC033943\|UniProtKB=A0A139WDV4	Tribolium castaneum	LDO