|
Gene Symbol(s):
|
JUN
|
| Organism: |
Homo sapiens |
| View Gene in Tree |
|
| Gene Name: |
Transcription factor Jun
|
| Gene ID: |
HGNC:6204
|
| Protein ID: |
P05412
|
| Enhancers: |
View enhancers for HUMAN|HGNC=6204|UniProtKB=P05412 |
| Genetic Variant Annotation: |
Annoq |
| Persistent Id: |
PTN002479243 |
| Alternate Ids: |
| CHEMBL4977(ChEMBL) |
Activator protein 1(Synonym) |
| ENSP00000503132(Ensembl_PRO) |
165160(MIM) |
| 3725(GeneID) |
HGNC:6204(HGNC) |
| Q96G93(AltAccession) |
JUN_HUMAN(UniProtKB-ID) |
| 49456409(GI) |
NP_002219(refSeq) |
| AAO22993(EMBL-CDS) |
ENSG00000177606(Ensembl) |
| ENST00000678696(Ensembl_TRS) |
BC009874(EMBL) |
JUN(Symbol) |
|
Show All
|
|
| GO MF Complete: |
cAMP response element binding, identical protein binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, GTPase activator activity, transcription cis-regulatory region binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, ubiquitin-like protein ligase binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA binding, DNA-binding transcription factor activity, RNA binding, protein binding, ubiquitin protein ligase binding, RNA polymerase II-specific DNA-binding transcription factor binding, R-SMAD binding, sequence-specific double-stranded DNA binding, general transcription initiation factor binding, enzyme binding
|
| GO BP Complete: |
positive regulation by host of viral transcription, negative regulation by host of viral transcription, SMAD protein signal transduction, transforming growth factor beta receptor signaling pathway, positive regulation of miRNA transcription, response to steroid hormone, positive regulation of transcription by RNA polymerase II, regulation of cell population proliferation, regulation of transcription by RNA polymerase II, negative regulation of transcription by RNA polymerase II, negative regulation of DNA binding, positive regulation of vascular associated smooth muscle cell proliferation, negative regulation of DNA-templated transcription, positive regulation of DNA-templated transcription, positive regulation of apoptotic process, release from viral latency, integrated stress response signaling, positive regulation of DNA-templated transcription initiation, regulation of cell cycle, response to endoplasmic reticulum stress
|
| GO CC Complete: |
nucleus, transcription regulator complex, euchromatin, RNA polymerase II transcription regulator complex, transcription factor AP-1 complex, nuclear chromosome, chromatin, nucleoplasm
|
| Reactome Pathways: |
Cellular Senescence, Toll Like Receptor 2 (TLR2) Cascade, Senescence-Associated Secretory Phenotype (SASP), Fc epsilon receptor (FCERI) signaling, MAPK family signaling cascades, Oxidative Stress Induced Senescence, RNA Polymerase II Transcription, Killing mechanisms, Cellular responses to stimuli, Signaling by ALK in cancer, Toll Like Receptor 10 (TLR10) Cascade, Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models, Infectious disease, Toll Like Receptor 7/8 (TLR7/8) Cascade, Diseases of signal transduction by growth factor receptors and second messengers, Activation of anterior HOX genes in hindbrain development during early embryogenesis, MyD88-independent TLR4 cascade , PIP3 activates AKT signaling, Toll Like Receptor TLR6:TLR2 Cascade, Regulation of PTEN gene transcription, Signaling by Nuclear Receptors, TRIF(TICAM1)-mediated TLR4 signaling , FCERI mediated MAPK activation, Signaling by NOTCH, Toll Like Receptor 4 (TLR4) Cascade, Pre-NOTCH Expression and Processing, MyD88:MAL(TIRAP) cascade initiated on plasma membrane, Parasitic Infection Pathways, Gene expression (Transcription), MyD88 cascade initiated on plasma membrane, MyD88 dependent cascade initiated on endosome, MAPK targets/ Nuclear events mediated by MAP kinases, Intracellular signaling by second messengers, MAP kinase activation, Cellular responses to stress, Signaling by Interleukins, Activation of HOX genes during differentiation, Pre-NOTCH Transcription and Translation, Toll Like Receptor 3 (TLR3) Cascade, PTEN Regulation, ESR-mediated signaling, Neurodegenerative Diseases, Diseases of programmed cell death, Signal Transduction, Innate Immune System, Developmental Biology, Transcriptional Regulation by TP53, Signaling by ALK fusions and activated point mutants, TP53 Regulates Transcription of DNA Repair Genes, Generic Transcription Pathway, Defective Intrinsic Pathway for Apoptosis, Activation of the AP-1 family of transcription factors, Toll Like Receptor 5 (TLR5) Cascade, Disease, TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation, Leishmania infection, Estrogen-dependent gene expression, MAPK6/MAPK4 signaling, Toll-like Receptor Cascades, Toll Like Receptor 9 (TLR9) Cascade, Cytokine Signaling in Immune system, Toll Like Receptor TLR1:TLR2 Cascade, Immune System, Interleukin-17 signaling, WNT5:FZD7-mediated leishmania damping
|
|
