PANTHER Gene Information   
Gene Symbol(s): SKIL
Organism: Homo sapiens
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Gene Name: Ski-like protein
Gene ID: HGNC:10897
Protein ID: P12757
Enhancers: View enhancers for HUMAN|HGNC=10897|UniProtKB=P12757
Genetic Variant Annotation: Annoq
Persistent Id: PTN002467143
Alternate Ids:
SKIL_HUMAN(UniProtKB-ID) 222143139(GI)
HGNC:10897(HGNC) 6498(GeneID)
Ski-related oncogene(Synonym) 165340(MIM)
U70730(EMBL) SKIL(Symbol)
ENSG00000136603(Ensembl) CAA79636(EMBL-CDS)
A6NGT1(AltAccession)
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PANTHER Classification
PANTHER Family: SKI ONCOGENE-RELATED (PTHR10005)
PANTHER Subfamily: SKI-LIKE PROTEIN (PTHR10005:SF3)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
SMAD binding
DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process: negative regulation of BMP signaling pathway
negative regulation of transcription by RNA polymerase II
regulation of transforming growth factor beta receptor signaling pathway
PANTHER GO-slim Cellular Component: nucleus
cytoplasm
transcription regulator complex
PANTHER protein class:
Pathway Categories: TGF-beta signaling pathway
   Co-activators or corepressors
Gonadotropin-releasing hormone receptor pathway
   SKIL

GO MF Complete: protein domain specific binding, identical protein binding, protein binding, SMAD binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, chromatin binding, DNA-binding transcription factor activity, RNA polymerase II-specific, protein-containing complex binding
GO BP Complete: response to cytokine, positive regulation of extrinsic apoptotic signaling pathway via death domain receptors, response to growth factor, spermatogenesis, positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage, lymphocyte homeostasis, transforming growth factor beta receptor signaling pathway, response to antibiotic, intrinsic apoptotic signaling pathway in response to DNA damage, extrinsic apoptotic signaling pathway via death domain receptors, negative regulation of transcription by RNA polymerase II, negative regulation of BMP signaling pathway, positive regulation of axonogenesis, negative regulation of cell differentiation, skeletal muscle tissue development, blastocyst formation, regulation of cell cycle, lens fiber cell differentiation, negative regulation of transforming growth factor beta receptor signaling pathway
GO CC Complete: nucleus, transcription regulator complex, PML body, cytoplasm, acrosomal vesicle, protein-containing complex, nucleoplasm
Reactome Pathways: Signal Transduction, Signaling by TGF-beta Receptor Complex, Gene expression (Transcription), RNA Polymerase II Transcription, Generic Transcription Pathway, Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer, Downregulation of SMAD2/3:SMAD4 transcriptional activity, Signaling by TGFB family members