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Gene Symbol(s):
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Atf2
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| Organism: |
Mus musculus |
| View Gene in Tree |
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| Gene Name: |
Cyclic AMP-dependent transcription factor ATF-2
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| Gene ID: |
MGI:109349
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| Protein ID: |
P16951
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| Persistent Id: |
PTN000447710 |
| Alternate Ids: |
| ENSMUSG00000027104(Ensembl) |
387487(GI) |
| S76659(EMBL) |
AAB21129(EMBL-CDS) |
| CHEMBL2176797(ChEMBL) |
11909(GeneID) |
| Atf2(Symbol) |
MXBP protein(Synonym) |
| ATF2_MOUSE(UniProtKB-ID) |
MGI:109349(MGI) |
Q64090(AltAccession) |
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Show All
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| GO MF Complete: |
cAMP response element binding protein binding, protein kinase binding, cAMP response element binding, identical protein binding, protein homodimerization activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, cis-regulatory region sequence-specific DNA binding, histone H2B acetyltransferase activity, DNA-binding transcription activator activity, RNA polymerase II-specific, sequence-specific DNA binding, chromatin binding, leucine zipper domain binding, DNA-binding transcription factor activity, RNA polymerase II-specific, protein-containing complex binding, DNA binding, DNA-binding transcription factor activity, protein binding, RNA polymerase II-specific DNA-binding transcription factor binding, promoter-specific chromatin binding, metal ion binding, protein heterodimerization activity, sequence-specific double-stranded DNA binding, histone H4 acetyltransferase activity
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| GO BP Complete: |
negative regulation of angiogenesis, detection of cell density, positive regulation of mitochondrial membrane permeability involved in apoptotic process, facial nucleus development, JNK cascade, positive regulation of DNA-binding transcription factor activity, hematopoietic progenitor cell differentiation, cellular response to leucine starvation, white fat cell differentiation, positive regulation of cardiac muscle myoblast proliferation, NK T cell differentiation, motor neuron apoptotic process, in utero embryonic development, cellular response to anisomycin, BMP signaling pathway, apoptotic process, mRNA transcription by RNA polymerase II, transcription initiation-coupled chromatin remodeling, p38MAPK cascade, response to osmotic stress, abducens nucleus development, hypoglossal nucleus development, response to organic cyclic compound, DNA damage response, amelogenesis, cellular response to virus, growth plate cartilage chondrocyte differentiation, protein import into nucleus, positive regulation of gene expression, positive regulation of transforming growth factor beta2 production, growth plate cartilage chondrocyte proliferation, negative regulation of epithelial cell proliferation, gene expression, vacuole organization, outflow tract morphogenesis, positive regulation of transcription by RNA polymerase II, positive regulation of neuron apoptotic process, negative regulation of transcription by RNA polymerase II, intrinsic apoptotic signaling pathway in response to hypoxia, MAPK cascade, heart development, liver development, mitotic intra-S DNA damage checkpoint signaling, neurofilament cytoskeleton organization, brainstem development, regulation of DNA-templated transcription, apoptotic process involved in development, regulation of cell cycle checkpoint, regulation of transcription by RNA polymerase II, adipose tissue development, hepatocyte apoptotic process, positive regulation of protein phosphorylation, lipid metabolic process, cellular response to oxidative stress
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| GO CC Complete: |
nucleus, CCAAT-binding factor complex, site of double-strand break, RNA polymerase II transcription regulator complex, cytoplasm, membrane, H4 histone acetyltransferase complex, mitochondrial outer membrane, chromatin, nucleoplasm
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| Reactome Pathways: |
Immune System, Toll Like Receptor TLR1:TLR2 Cascade, Toll Like Receptor 5 (TLR5) Cascade, Toll-like Receptor Cascades, Toll Like Receptor 4 (TLR4) Cascade, Toll Like Receptor 9 (TLR9) Cascade, Interleukin-17 signaling, MyD88:MAL(TIRAP) cascade initiated on plasma membrane, Chromatin modifying enzymes, TRIF(TICAM1)-mediated TLR4 signaling , MAP kinase activation, MyD88-independent TLR4 cascade , Toll Like Receptor TLR6:TLR2 Cascade, Chromatin organization, Innate Immune System, MyD88 cascade initiated on plasma membrane, MyD88 dependent cascade initiated on endosome, Toll Like Receptor 2 (TLR2) Cascade, MAPK targets/ Nuclear events mediated by MAP kinases, Activation of the AP-1 family of transcription factors, TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation, Signaling by Interleukins, Toll Like Receptor 7/8 (TLR7/8) Cascade, Cytokine Signaling in Immune system, Toll Like Receptor 10 (TLR10) Cascade, Toll Like Receptor 3 (TLR3) Cascade, HATs acetylate histones
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