PANTHER Gene Information   
Gene Symbol(s): Adcy6
Organism: Rattus norvegicus
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Gene Name: Adenylate cyclase type 6
Gene ID: 2035
Protein ID: Q03343
Persistent Id: PTN000229451
Alternate Ids:
ACVI(Synonym) 4.6.1.1 {ECO:0000269|PubMed:1409703, ECO:0000269|PubMed:15385642, ECO:0000269|PubMed:17110384, ECO:0000269|PubMed:21606183, ECO:0000269|PubMed:9391159}(EC)
2035(RGD) 202713(GI)
CHEMBL2095179(ChEMBL) NP_036953(refSeq)
L01115(EMBL) 25289(GeneID)
AAA40678(EMBL-CDS) ADCY6_RAT(UniProtKB-ID)
Adcy6(Symbol)
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PANTHER Classification
PANTHER Family: ADENYLATE CYCLASE TYPE 1 (PTHR45627)
PANTHER Subfamily: ADENYLATE CYCLASE TYPE 6 (PTHR45627:SF11)  
PANTHER GO-slim Molecular Function: adenylate cyclase activity
PANTHER GO-slim Biological Process: adenylate cyclase-activating G protein-coupled receptor signaling pathway
PANTHER GO-slim Cellular Component: plasma membrane
PANTHER protein class: adenylate cyclase
Pathway Categories: Endothelin signaling pathway
   Adenylate cyclase
GABA-B receptor II signaling
   adenylate cyclase
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   Adenylyl cyclase
Inflammation mediated by chemokine and cytokine signaling pathway
   adenylate cyclase
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein kinase C binding, calcium- and calmodulin-responsive adenylate cyclase activity, ATP binding, protein kinase binding, scaffold protein binding, metal ion binding, SNARE binding, signaling receptor binding, adenylate cyclase activity
GO BP Complete: cAMP biosynthetic process, adenylate cyclase-activating dopamine receptor signaling pathway, renal water homeostasis, adenylate cyclase-activating serotonin receptor signaling pathway, cellular response to forskolin, cellular response to vasopressin, adenylate cyclase-activating G protein-coupled receptor signaling pathway, circadian rhythm, cellular response to prostaglandin E stimulus, maintenance of protein location in plasma membrane, negative regulation of neuron projection development, cellular response to catecholamine stimulus, negative regulation of urine volume, blood vessel diameter maintenance, intracellular signal transduction
GO CC Complete: microvillus membrane, endosome, sarcolemma, membrane, cilium, stereocilium, plasma membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Signaling by GPCR, Signaling by Hedgehog, GABA B receptor activation, Integration of energy metabolism, Neuronal System, Transmission across Chemical Synapses, Neurotransmitter receptors and postsynaptic signal transmission, Opioid Signalling, Adenylate cyclase activating pathway, G alpha (i) signalling events, G alpha (z) signalling events, GABA receptor activation, PKA activation, Hedgehog 'off' state, DAG and IP3 signaling, PLC beta mediated events, Adrenaline,noradrenaline inhibits insulin secretion, Signal Transduction, Calmodulin induced events, Ca-dependent events, CaM pathway, PKA-mediated phosphorylation of CREB, Adenylate cyclase inhibitory pathway, Metabolism, GPCR downstream signalling, Regulation of insulin secretion, Activation of GABAB receptors, G-protein mediated events, Intracellular signaling by second messengers

Orthologs