PANTHER Gene Information

Gene Symbol(s):

Inhbb

Organism:

Mus musculus

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Gene Name:

Inhibin beta B chain

Gene ID:

MGI:96571

Protein ID:

Q04999

Persistent Id:

PTN000218182

Alternate Ids:

INHBB_MOUSE(UniProtKB-ID)	Q3V1N0(AltAccession)
X83376(EMBL)	MGI:96571(MGI)
Inhbb(Symbol)	ENSMUST00000038765(Ensembl_TRS)
ENSMUSP00000044918(Ensembl_PRO)	Activin beta-B chain(Synonym)
BAE21120(EMBL-CDS)	16324(GeneID)
29179420(GI)	ENSMUSG00000037035(Ensembl)
NP_032407(refSeq)
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PANTHER Classification

PANTHER Family:	TGF-BETA FAMILY (PTHR11848)
PANTHER Subfamily:	INHIBIN BETA B CHAIN (PTHR11848:SF29)
PANTHER GO-slim Molecular Function:	cytokine activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	extracellular space
PANTHER protein class:	growth factor

Pathway Categories:

TGF-beta signaling pathway

Transforming growth factor beta

Gonadotropin-releasing hormone receptor pathway

Inhba/b

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	growth factor activity, protein homodimerization activity, cytokine activity, hormone activity
GO BP Complete:	response to wounding, apoptotic signaling pathway, female gonad development, fat cell differentiation, negative regulation of insulin secretion, cellular response to Thyroglobulin triiodothyronine, cellular response to insulin stimulus, activin receptor signaling pathway, cellular response to thyroid hormone stimulus, negative regulation of follicle-stimulating hormone secretion, cellular response to calcium ion, response to insecticide, seminiferous tubule development, cellular response to leptin stimulus, positive regulation of follicle-stimulating hormone secretion, cellular response to cholesterol, negative regulation of hepatocyte growth factor production, spermatogenesis, cellular response to starvation, positive regulation of ovulation, pituitary gland development, eye development, oocyte development, cellular response to cAMP, cellular response to interleukin-1, response to gonadotropin, positive regulation of apoptotic signaling pathway
GO CC Complete:	extracellular space, perinuclear region of cytoplasm, extracellular region, cell periphery

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Antagonism of Activin by Follistatin, Peptide hormone metabolism, Glycoprotein hormones, Signal Transduction, Signaling by Activin, Signaling by TGFB family members, Peptide hormone biosynthesis, Metabolism of proteins

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6067\|UniProtKB=P09529	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000046739.1\|UniProtKB=A0A2I3TNV9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015308.3\|UniProtKB=G3RH13	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000060196.1\|UniProtKB=A0A5F8ALK5	Macaca mulatta	LDO
RAT\|RGD=2913\|UniProtKB=P17491	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000049058.1\|UniProtKB=A0A3Q1LMU4	Bos taurus	LDO
BOVIN\|Gene=INHBB\|UniProtKB=P42917	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000038610.2\|UniProtKB=A0A287BPF5	Sus scrofa	LDO
PIG\|Gene=INHBB\|UniProtKB=P04088	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000014285.3\|UniProtKB=F7A1Y1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000042797.2\|UniProtKB=A0A337RU16	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845027084.1\|UniProtKB=A0A8I3SAJ4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000042727.1\|UniProtKB=A0A5F8HIU4	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000042798.1\|UniProtKB=A0A6I8NNB7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010018937.1\|UniProtKB=R4GIS0	Gallus gallus	LDO
CHICK\|Gene=INHBB\|UniProtKB=P27093	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000004094.4\|UniProtKB=R4GDL9	Anolis carolinensis	LDO
XENLA\|Gene=inhbb.S\|UniProtKB=A0A1L8ENH9	Xenopus laevis	LDO
XENLA\|Gene=inhbb.L\|UniProtKB=Q91350	Xenopus laevis	LDO
XENTR\|Ensembl=ENSXETG00000044060\|UniProtKB=A0A803JF31	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000001340.2\|UniProtKB=H2L746	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-990415-2\|UniProtKB=B0S7E0	Danio rerio	O
DANRE\|Gene=LOC100332902\|UniProtKB=A0A8M2BK93	Danio rerio	O
DANRE\|Gene=LOC101887111\|UniProtKB=A0A8M2BK69	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000002019.1\|UniProtKB=W5M1T3	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118423922\|UniProtKB=A0A9J7N3A4	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC100147806\|UniProtKB=B2YGG4	Strongylocentrotus purpuratus	O
CAEEL\|Gene_ORFName=CELE_Y46E12BL.1\|UniProtKB=A0A8S4QGI4	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG20656\|UniProtKB=A8XYB0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00107742\|UniProtKB=A0A2A6C891	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00278464\|UniProtKB=A0A454Y4J7	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00272968\|UniProtKB=A0A454XJT7	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00273955\|UniProtKB=A0A2A6B6K2	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00096903\|UniProtKB=A0A2A6C8S7	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0024913\|UniProtKB=O61643	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP000342\|UniProtKB=A0A1S4G8N6	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC015808\|UniProtKB=D2A422	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_305466\|UniProtKB=E9FWU5	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW008819\|UniProtKB=B7PZ52	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW016200\|UniProtKB=B7P4B4	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG111242\|UniProtKB=T1EF97	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g196852\|UniProtKB=A7RGJ4	Nematostella vectensis	O