PANTHER Gene Information   
Gene Symbol(s): MYLK
Organism: Homo sapiens
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Gene Name: Myosin light chain kinase, smooth muscle
Gene ID: HGNC:7590
Protein ID: Q15746
Enhancers: View enhancers for HUMAN|HGNC=7590|UniProtKB=Q15746
Genetic Variant Annotation: Annoq
Persistent Id: PTN002557125
Alternate Ids:
194373985(GI) BC100761(EMBL)
MYLK(Synonym) BAG37033(EMBL-CDS)
613780(MIM) ENSG00000065534(Ensembl)
4638(GeneID) HGNC:7590(HGNC)
MYLK_HUMAN(UniProtKB-ID) CHEMBL2428(ChEMBL)
XP_011511162(refSeq) D3DN97(AltAccession)
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PANTHER Classification
PANTHER Family: IMMUNOGLOBULIN (PTHR47633)
PANTHER Subfamily: MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE (PTHR47633:SF1)  
PANTHER GO-slim Molecular Function: protein kinase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:
Pathway Categories: Inflammation mediated by chemokine and cytokine signaling pathway
   Myosin light chain kinase
Cytoskeletal regulation by Rho GTPase
   Myosin light chain kinase

GO MF Complete: ATP binding, scaffold protein binding, calmodulin binding, protein binding, actin binding, metal ion binding, myosin light chain kinase activity
GO BP Complete: bleb assembly, positive regulation of wound healing, smooth muscle contraction, cellular hypotonic response, positive regulation of calcium ion transport, regulation of synaptic vesicle endocytosis, protein phosphorylation, tonic smooth muscle contraction, positive regulation of cell migration, aorta smooth muscle tissue morphogenesis
GO CC Complete: cytoplasm, cleavage furrow, stress fiber, actin cytoskeleton, cytosol, synapse, plasma membrane, lamellipodium
Reactome Pathways: Signal Transduction, Smooth Muscle Contraction, RHO GTPases activate PAKs, RHO GTPase Effectors, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Signaling by Rho GTPases, Muscle contraction