Pathway Component Details
| Name: | Myosin light chain kinase (MLCK) |
| Definition: | Ser/Thr kinase that phosphorylate myosin light chain, thus activating myosin filament formation. |
| Category ID: | P00877 |
| Synonyms: | |
| Upstream: |
Rho-associated coiled-coil Ser/Thr specific kinase
(ROCK)
|
| Downstream: |
Myosin
|
| Number Families/Subfamilies: | 4 |
| Number of Associated Sequences: | 12 |
| GO Molecular Function: |
-
|
| GO Biological Process: |
-
|
| GO Cellular Component: |
-
|
| PANTHER protein class: |
-
|
| References: | OMIM:600922 |
Sequence Association
| Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
| PTHR24347:SF373 | A0A8V0YPY7 | Myosin light chain kinase 2, skeletal_cardiac muscle | IDA | PubMed:11157482 |
| A0A8V0YPY7 | Myosin light chain kinase 2, skeletal_cardiac muscle | IDA | OMIM:600922 | |
| H2QK55 | Myosin light chain kinase 2, skeletal_cardiac muscle | ISS | PubMed:11157482 | |
| H2QK55 | Myosin light chain kinase 2, skeletal_cardiac muscle | ISS | OMIM:600922 | |
| P20689 | Myosin light chain kinase 2, skeletal_cardiac muscle | IDA | PubMed:11157482 | |
| P20689 | Myosin light chain kinase 2, skeletal_cardiac muscle | IDA | OMIM:600922 | |
| Q8VCR8 | Myosin light chain kinase 2, skeletal_cardiac muscle | ISS | PubMed:11157482 | |
| Q8VCR8 | Myosin light chain kinase 2, skeletal_cardiac muscle | ISS | OMIM:600922 | |
| Q9H1R3 | Myosin light chain kinase 2, skeletal_cardiac muscle | IDA | PubMed:11157482 | |
| Q9H1R3 | Myosin light chain kinase 2, skeletal_cardiac muscle | IDA | OMIM:600922 | |
| PTHR24347:SF393 | Q23260 | Protein kinase domain-containing protein | IDA | |
| PTHR24347:SF394 | H2QB15 | Myosin light chain kinase 3 | ISS | PubMed:11157482 |
| H2QB15 | Myosin light chain kinase 3 | ISS | OMIM:600922 | |
| Q32MK0 | Myosin light chain kinase 3 | IDA | PubMed:11157482 | |
| Q32MK0 | Myosin light chain kinase 3 | IDA | OMIM:600922 | |
| PTHR47633:SF1 | A0A2I3TJW3 | Myosin light chain kinase, smooth muscle | ISS | PubMed:11157482 |
| A0A2I3TJW3 | Myosin light chain kinase, smooth muscle | ISS | OMIM:600922 | |
| P11799 | Myosin light chain kinase, smooth muscle | IDA | PubMed:11157482 | |
| P11799 | Myosin light chain kinase, smooth muscle | IDA | OMIM:600922 | |
| Q15746 | Myosin light chain kinase, smooth muscle | IDA | PubMed:11157482 | |
| Q15746 | Myosin light chain kinase, smooth muscle | IDA | OMIM:600922 | |
| Q28824 | Myosin light chain kinase, smooth muscle | IDA | PubMed:11157482 | |
| Q28824 | Myosin light chain kinase, smooth muscle | IDA | OMIM:600922 |
