Pathway Component Details
| Name: | Rho-associated coiled-coil Ser/Thr specific kinase (ROCK) |
| Definition: | Rho-associated coiled-coil Ser/Thr specific kinase. Specific pharmacological inhibitor, Y-27632, inhibits actin polymerization-dependent contractile force. |
| Category ID: | P00881 |
| Synonyms: | |
| Upstream: |
Rho
P21-activated kinase (PAK) |
| Downstream: |
Myosin light chain kinase
(MLCK)
|
| Number Families/Subfamilies: | 1 |
| Number of Associated Sequences: | 5 |
| GO Molecular Function: |
-
|
| GO Biological Process: |
-
|
| GO Cellular Component: |
-
|
| PANTHER protein class: |
-
|
| References: |
Sequence Association
| Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
| PTHR22988:SF33 | A0A5F8H6U5 | non-specific serine_threonine protein kinase | ISS | PubMed:10779382 |
| H9EPT5 | Rho-associated protein kinase | ISS | PubMed:10779382 | |
| P70335 | Rho-associated protein kinase 1 | IDA | PubMed:10779382 | |
| Q13464 | Rho-associated protein kinase 1 | ISS | PubMed:10779382 | |
| Q63644 | Rho-associated protein kinase 1 | ISS | PubMed:10779382 |
