PANTHER Gene Information

Gene Symbol(s):

id:ibd1250

Organism:

Danio rerio

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Gene Name:

Ski oncogene

Gene ID:

ZDB-GENE-990715-9

Protein ID:

Q1ECW8

Persistent Id:

PTN000000416

Alternate Ids:

108742030(GI)	BC117641(EMBL)
NM_130935(refSeq)	30101(GeneID)
ZDB-GENE-990715-9(ZFIN)	Q1ECW8_DANRE(UniProtKB-ID)
AAI17642(EMBL-CDS)	Q1ECW8(Synonym)
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PANTHER Classification

PANTHER Family:	SKI ONCOGENE-RELATED (PTHR10005)
PANTHER Subfamily:	SKI ONCOGENE (PTHR10005:SF15)
PANTHER GO-slim Molecular Function:	RNA polymerase II cis-regulatory region sequence-specific DNA binding SMAD binding DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process:	negative regulation of BMP signaling pathway negative regulation of transcription by RNA polymerase II regulation of transforming growth factor beta receptor signaling pathway
PANTHER GO-slim Cellular Component:	nucleus cytoplasm transcription regulator complex
PANTHER protein class:

Pathway Categories:

TGF-beta signaling pathway

Co-activators or corepressors

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	SMAD binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	negative regulation of transcription by RNA polymerase II, negative regulation of BMP signaling pathway, heart looping, negative regulation of transforming growth factor beta receptor signaling pathway, cardiac conduction, dorsal/ventral pattern formation, cartilage development
GO CC Complete:	nucleus, transcription regulator complex, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

RNA Polymerase II Transcription, Gene expression (Transcription), Downregulation of SMAD2/3:SMAD4 transcriptional activity, Signaling by TGFB family members, Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer, Generic Transcription Pathway, Signal Transduction, Signaling by TGF-beta Receptor Complex

Orthologs

ID	Organism	Type
HUMAN\|HGNC=10896\|UniProtKB=P12755	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000000047.4\|UniProtKB=H2PXU5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010476.3\|UniProtKB=G3R4L4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000010280.4\|UniProtKB=F6PUV5	Macaca mulatta	LDO
MOUSE\|MGI=MGI=98310\|UniProtKB=Q60698	Mus musculus	LDO
RAT\|RGD=1565591\|UniProtKB=A0A0G2K628	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000038716.4\|UniProtKB=F1N727	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000040944.3\|UniProtKB=A0A287AGC8	Sus scrofa	LDO
HORSE\|Gene=SKI\|UniProtKB=Q9TUG2	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000012543.4\|UniProtKB=A0A9L0RU01	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000026707.4\|UniProtKB=M3X092	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845016973.1\|UniProtKB=A0A8I3P330	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000020914.4\|UniProtKB=H9H7S6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000010922.4\|UniProtKB=A0A6I8PL30	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010020038.1\|UniProtKB=E1BSJ7	Gallus gallus	LDO
CHICK\|Gene=SKI\|UniProtKB=P49140	Gallus gallus	LDO
XENLA\|Gene=ski\|UniProtKB=Q02225	Xenopus laevis	O
XENLA\|Gene=ski.L\|UniProtKB=A0A1L8FM01	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-494028\|UniProtKB=A0A8J0R5Q3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000016855.2\|UniProtKB=A0A3B3HP51	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000005728.1\|UniProtKB=W5MEW2	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000000087.3\|UniProtKB=F6TS32	Ciona intestinalis	O
BRAFL\|Gene=LOC118429858\|UniProtKB=A0A9J7N7S3	Branchiostoma floridae	O
PRIPA\|EnsemblGenome=WBGene00111802\|UniProtKB=A0A2A6B5M9	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0085450\|UniProtKB=Q00G30	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029919\|UniProtKB=A0A903XX60	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC033943\|UniProtKB=A0A139WDV4	Tribolium castaneum	O