PANTHER Gene Information   
Gene Symbol(s): Ski
Organism: Mus musculus
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Gene Name: Ski oncogene
Gene ID: MGI:98310
Protein ID: Q60698
Persistent Id: PTN000000400
Alternate Ids:
Ski(Symbol) SKI(Synonym)
AAL30825(EMBL-CDS) AF435852(EMBL)
Q8VIL5(AltAccession) 68067481(GI)
MGI:98310(MGI) SKI_MOUSE(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: SKI ONCOGENE-RELATED (PTHR10005)
PANTHER Subfamily: SKI ONCOGENE (PTHR10005:SF15)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
SMAD binding
DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process: negative regulation of BMP signaling pathway
negative regulation of transcription by RNA polymerase II
regulation of transforming growth factor beta receptor signaling pathway
PANTHER GO-slim Cellular Component: nucleus
cytoplasm
transcription regulator complex
PANTHER protein class:
Pathway Categories: TGF-beta signaling pathway
   Co-activators or corepressors

GO MF Complete: protein kinase binding, zinc ion binding, protein domain specific binding, identical protein binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, chromatin binding, histone deacetylase inhibitor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, protein binding, ubiquitin protein ligase binding, SMAD binding, transcription corepressor activity, DNA-binding transcription factor binding
GO BP Complete: retina development in camera-type eye, negative regulation of cell population proliferation, roof of mouth development, nose morphogenesis, bone morphogenesis, positive regulation of DNA binding, positive regulation of transcription by RNA polymerase II, lens morphogenesis in camera-type eye, olfactory bulb development, face morphogenesis, negative regulation of osteoblast differentiation, negative regulation of transcription by RNA polymerase II, fibroblast proliferation, anterior/posterior axis specification, embryonic limb morphogenesis, myelination in peripheral nervous system, neural tube closure, negative regulation of fibroblast proliferation, skeletal muscle fiber development, negative regulation of activin receptor signaling pathway, camera-type eye development, somatic stem cell population maintenance, protein heterotrimerization, negative regulation of SMAD protein signal transduction, cardiac muscle cell proliferation, negative regulation of BMP signaling pathway, camera-type eye morphogenesis, negative regulation of Schwann cell proliferation, negative regulation of transcription by RNA polymerase III, myotube differentiation, negative regulation of transforming growth factor beta receptor signaling pathway
GO CC Complete: nucleus, transcription regulator complex, centrosome, nuclear body, PML body, cytoplasm, transcription repressor complex, protein-containing complex, nucleoplasm
Reactome Pathways: Signaling by BMP, Downregulation of SMAD2/3:SMAD4 transcriptional activity, Signal Transduction, Signaling by TGFB family members, Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer, Generic Transcription Pathway, Signaling by TGF-beta Receptor Complex, Gene expression (Transcription), RNA Polymerase II Transcription