PANTHER Gene Information   
Gene Symbol(s): CITED2
Organism: Homo sapiens
View Gene in Tree
Tree Reduced Tree  
Tree Reduced Tree
Gene Name: Cbp_p300-interacting transactivator 2
Gene ID: HGNC:1987
Protein ID: Q99967
Enhancers: View enhancers for HUMAN|HGNC=1987|UniProtKB=Q99967
Genetic Variant Annotation: Annoq
Persistent Id: PTN002497737
Alternate Ids:
270288754(GI) AAD10055(EMBL-CDS)
O95426(AltAccession) CITE2_HUMAN(UniProtKB-ID)
NM_001168389(refSeq) HGNC:1987(HGNC)
10370(GeneID) ENSG00000164442(Ensembl)
CITED2(Symbol) BC004377(EMBL)
614433(MIM) CITE2(Synonym)
Show All

PANTHER Classification
PANTHER Family: MELANOCYTE SPECIFIC GENE RELATED CITED (PTHR17045)
PANTHER Subfamily: CBP_P300-INTERACTING TRANSACTIVATOR 2 (PTHR17045:SF7)  
PANTHER GO-slim Molecular Function: transcription coactivator activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component: nucleus
PANTHER protein class: transcription cofactor
Pathway Categories: TGF-beta signaling pathway
   Co-activators or corepressors

GO MF Complete: protein domain specific binding, histone acetyltransferase binding, protein binding, transcription coactivator activity, SMAD binding, RNA polymerase II-specific DNA-binding transcription factor binding, transcription corepressor activity, LBD domain binding, chromatin binding, molecular function activator activity
GO BP Complete: negative regulation of cardiac muscle cell proliferation, response to estrogen, male gonad development, positive regulation of peroxisome proliferator activated receptor signaling pathway, positive regulation of cell-cell adhesion, transforming growth factor beta receptor signaling pathway, decidualization, sex determination, lens morphogenesis in camera-type eye, hematopoietic progenitor cell differentiation, response to hypoxia, skeletal muscle cell differentiation, negative regulation of DNA-templated transcription, positive regulation of DNA-templated transcription, heart looping, cellular response to hypoxia, trophectodermal cell differentiation, determination of left/right asymmetry in lateral mesoderm, peripheral nervous system development, negative regulation of gene expression, central nervous system development, positive regulation of gene expression, granulocyte differentiation, negative regulation of cell migration, cell population proliferation, pulmonary artery morphogenesis, positive regulation of male gonad development, uterus development, cellular senescence, outflow tract morphogenesis, bone morphogenesis, positive regulation of cell cycle, spleen development, endocardial cushion development, vasculogenesis, positive regulation of transcription by RNA polymerase II, regulation of animal organ formation, embryonic placenta development, response to mechanical stimulus, nodal signaling pathway, thymus development, negative regulation of transcription by RNA polymerase II, heart development, neural tube closure, liver development, response to fluid shear stress, left/right axis specification, embryonic heart tube left/right pattern formation, erythrocyte development, cardiac neural crest cell development involved in heart development, cranial nerve morphogenesis, embryonic process involved in female pregnancy, left/right pattern formation, ventricular septum morphogenesis, determination of left/right symmetry, negative regulation of apoptotic process, embryonic camera-type eye morphogenesis, adrenal cortex formation, positive regulation of transforming growth factor beta receptor signaling pathway
GO CC Complete: nucleus, cytoplasm, intracellular membrane-bounded organelle, cytosol, protein-containing complex, chromatin, nucleoplasm
Reactome Pathways: Regulation of gene expression by Hypoxia-inducible Factor, Cellular responses to stress, RNA Polymerase II Transcription, Generic Transcription Pathway, Gene expression (Transcription), FOXO-mediated transcription, Cellular responses to stimuli, Activation of the TFAP2 (AP-2) family of transcription factors, Cellular response to hypoxia, Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors, TFAP2 (AP-2) family regulates transcription of other transcription factors, FOXO-mediated transcription of cell death genes