PANTHER Gene Information   
Gene Symbol(s): PRKD2
Organism: Homo sapiens
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Gene Name: Serine_threonine-protein kinase D2
Gene ID: HGNC:17293
Protein ID: Q9BZL6
Enhancers: View enhancers for HUMAN|HGNC=17293|UniProtKB=Q9BZL6
Genetic Variant Annotation: Annoq
Persistent Id: PTN002506450
Alternate Ids:
4884154(GI) AK074673(EMBL)
BAG62084(EMBL-CDS) nPKC-D2(Synonym)
KPCD2_HUMAN(UniProtKB-ID) Q8TB08(AltAccession)
2.7.11.13 {ECO:0000269|PubMed:11062248, ECO:0000269|PubMed:12058027, ECO:0000269|PubMed:17962809, ECO:0000269|PubMed:28428613}(EC) PRKD2(Symbol)
CHEMBL4900(ChEMBL) ENSG00000105287(Ensembl)
HGNC:17293(HGNC) 607074(MIM)
25865(GeneID)
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PANTHER Classification
PANTHER Family: PROTEIN KINASE C, MU (PTHR22968)
PANTHER Subfamily: SERINE_THREONINE-PROTEIN KINASE D2 (PTHR22968:SF12)  
PANTHER GO-slim Molecular Function: protein serine/threonine kinase activity
PANTHER GO-slim Biological Process: intracellular signal transduction
phospholipase C-activating G protein-coupled receptor signaling pathway
PANTHER GO-slim Cellular Component: cytosol
PANTHER protein class: non-receptor serine/threonine protein kinase
Pathway Categories: VEGF signaling pathway
   Protein kinase C
CCKR signaling map
   PRKD2
Angiogenesis
   Protein kinase B
EGF receptor signaling pathway
   PKC

GO MF Complete: protein kinase C binding, diacylglycerol-dependent, calcium-independent serine/threonine kinase activity, ATP binding, protein binding, metal ion binding, protein kinase activity, protein serine/threonine kinase activity, calcium,diacylglycerol-dependent serine/threonine kinase activity, protein serine kinase activity, diacylglycerol-dependent serine/threonine kinase activity
GO BP Complete: endothelial tube morphogenesis, positive regulation of fibroblast growth factor receptor signaling pathway, protein autophosphorylation, cell adhesion, positive regulation of cell adhesion, protein phosphorylation, positive regulation of transcription by RNA polymerase II, positive regulation of DNA-binding transcription factor activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of angiogenesis, angiogenesis, positive regulation of vascular endothelial growth factor receptor signaling pathway, positive regulation of endothelial cell chemotaxis, positive regulation of endothelial cell migration, positive regulation of DNA biosynthetic process, intracellular signal transduction, T cell receptor signaling pathway, sphingolipid biosynthetic process, positive regulation of interleukin-2 production, adaptive immune response, phospholipase C-activating G protein-coupled receptor signaling pathway, positive regulation of blood vessel endothelial cell migration, positive regulation of T cell receptor signaling pathway, positive regulation of interleukin-8 production, vascular endothelial growth factor receptor signaling pathway, regulation of T cell apoptotic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of endothelial cell proliferation, cellular response to vascular endothelial growth factor stimulus, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation
GO CC Complete: nucleus, cytoplasm, cytosol, Golgi apparatus, plasma membrane, nucleoplasm
Reactome Pathways: Metabolism, Sphingolipid metabolism, Metabolism of lipids, Sphingolipid de novo biosynthesis