PANTHER Gene Information   
Gene Symbol(s): FGF22
Organism: Homo sapiens
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Gene Name: Fibroblast growth factor 22
Gene ID: HGNC:3679
Protein ID: Q9HCT0
Enhancers: View enhancers for HUMAN|HGNC=3679|UniProtKB=Q9HCT0
Genetic Variant Annotation: Annoq
Persistent Id: PTN002479503
Alternate Ids:
FGF22_HUMAN(UniProtKB-ID) BC137444(EMBL)
NM_020637(refSeq) B2RPH4(AltAccession)
ENSG00000070388(Ensembl) 13626689(GI)
ENST00000215530(Ensembl_TRS) AAQ93357(EMBL-CDS)
FGF22(Synonym) FGF22(Symbol)
605831(MIM) CHEMBL2362983(ChEMBL)
HGNC:3679(HGNC) ENSP00000215530(Ensembl_PRO)
27006(GeneID)
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PANTHER Classification
PANTHER Family: FIBROBLAST GROWTH FACTOR (PTHR11486)
PANTHER Subfamily: FIBROBLAST GROWTH FACTOR 22 (PTHR11486:SF41)  
PANTHER GO-slim Molecular Function: growth factor activity
fibroblast growth factor receptor binding
PANTHER GO-slim Biological Process: regulation of cell migration
fibroblast growth factor receptor signaling pathway
positive regulation of protein phosphorylation
cell differentiation
positive regulation of MAPK cascade
positive regulation of gene expression
positive regulation of cell population proliferation
animal organ morphogenesis
PANTHER GO-slim Cellular Component: extracellular space
cytoplasm
PANTHER protein class: growth factor
Pathway Categories: FGF signaling pathway
   fibroblast growth factor

GO MF Complete: growth factor activity, fibroblast growth factor receptor binding
GO BP Complete: positive regulation of cell population proliferation, cell differentiation, fibroblast growth factor receptor signaling pathway, neurogenesis, positive regulation of MAPK cascade, regulation of cell migration
GO CC Complete: extracellular space, cytoplasm, extracellular region
Reactome Pathways: PI3K Cascade, PI3K/AKT Signaling in Cancer, FRS-mediated FGFR1 signaling, MAPK family signaling cascades, FGFR2 mutant receptor activation, IRS-mediated signalling, Diseases of signal transduction by growth factor receptors and second messengers, Signal Transduction, Signaling by FGFR, IRS-related events triggered by IGF1R, FGFR2b ligand binding and activation, PIP3 activates AKT signaling, Negative regulation of FGFR1 signaling, Negative regulation of FGFR2 signaling, IGF1R signaling cascade, SHC-mediated cascade:FGFR1, Constitutive Signaling by Aberrant PI3K in Cancer, FGFR1b ligand binding and activation, PI-3K cascade:FGFR1, FRS-mediated FGFR2 signaling, Signaling by Receptor Tyrosine Kinases, RAF/MAP kinase cascade, Activated point mutants of FGFR2, FGFRL1 modulation of FGFR1 signaling, Signaling by FGFR in disease, Downstream signaling of activated FGFR1, Signaling by FGFR2 in disease, MAPK1/MAPK3 signaling, Phospholipase C-mediated cascade; FGFR2, Disease, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), Signaling by Insulin receptor, Insulin receptor signalling cascade, Negative regulation of the PI3K/AKT network, Phospholipase C-mediated cascade: FGFR1, FGFR1 ligand binding and activation, Signaling by FGFR1, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, Signaling by FGFR2, FGFR2 ligand binding and activation, SHC-mediated cascade:FGFR2, PI-3K cascade:FGFR2, Downstream signaling of activated FGFR2, Intracellular signaling by second messengers