Pathway Component Details
| Name: | p21 activated kinase (PAK) |
| Definition: | PAK is a member of a family of serine/threonine kinases related to yeast Ste20. |
| Category ID: | P00517 |
| Synonyms: | |
| Upstream: | |
| Downstream: |
Stathmin
(Op18/stathmin)
LIM domain kinase 1 (LIMK) |
| Number Families/Subfamilies: | 8 |
| Number of Associated Sequences: | 47 |
| GO Molecular Function: |
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| GO Biological Process: |
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| GO Cellular Component: |
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| PANTHER protein class: |
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| References: | OMIM:602590 |
Sequence Association
| Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
| PTHR48015:SF17 | A0A6I8SQB3 | non-specific serine_threonine protein kinase | ISS | |
| A0A8I3MTF5 | non-specific serine_threonine protein kinase | ISS | ||
| B5DF62 | P21 (RAC1) activated kinase 4 | ISS | ||
| F6Z9H7 | non-specific serine_threonine protein kinase | ISS | ||
| O96013 | Serine_threonine-protein kinase PAK 4 | ISS | ||
| Q17QZ0 | non-specific serine_threonine protein kinase | ISS | ||
| Q8BTW9 | Serine_threonine-protein kinase PAK 4 | ISS | ||
| PTHR48015:SF19 | D3ZQ51 | P21 (RAC1) activated kinase 6 | ISS | |
| E1BA03 | non-specific serine_threonine protein kinase | ISS | ||
| F6TWF0 | non-specific serine_threonine protein kinase | ISS | ||
| H2Q960 | non-specific serine_threonine protein kinase | ISS | ||
| Q3ULB5 | Serine_threonine-protein kinase PAK 6 | ISS | ||
| Q9NQU5 | Serine_threonine-protein kinase PAK 6 | ISS | ||
| PTHR48015:SF20 | A0A8I3NMF7 | P21 (RAC1) activated kinase 1 | ISS | PubMed:10508610 |
| A0A8I3NMF7 | P21 (RAC1) activated kinase 1 | ISS | PubMed:11689432 | |
| A0A8I3NMF7 | P21 (RAC1) activated kinase 1 | ISS | PubMed:12912914 | |
| A0A8I3NMF7 | P21 (RAC1) activated kinase 1 | ISS | PubMed:14580336 | |
| A0A8I3NMF7 | P21 (RAC1) activated kinase 1 | ISS | PubMed:15187108 | |
| E1C3P6 | non-specific serine_threonine protein kinase | ISS | PubMed:10508610 | |
| E1C3P6 | non-specific serine_threonine protein kinase | ISS | PubMed:11689432 | |
| E1C3P6 | non-specific serine_threonine protein kinase | ISS | PubMed:12912914 | |
| E1C3P6 | non-specific serine_threonine protein kinase | ISS | PubMed:14580336 | |
| E1C3P6 | non-specific serine_threonine protein kinase | ISS | PubMed:15187108 | |
| H9EM79 | non-specific serine_threonine protein kinase | ISS | PubMed:10508610 | |
| H9EM79 | non-specific serine_threonine protein kinase | ISS | PubMed:11689432 | |
| H9EM79 | non-specific serine_threonine protein kinase | ISS | PubMed:12912914 | |
| H9EM79 | non-specific serine_threonine protein kinase | ISS | PubMed:14580336 | |
| H9EM79 | non-specific serine_threonine protein kinase | ISS | PubMed:15187108 | |
| O88643 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:10508610 | |
| O88643 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:11689432 | |
| O88643 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:12912914 | |
| O88643 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:14580336 | |
| O88643 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:15187108 | |
| P35465 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:10508610 | |
| P35465 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:11689432 | |
| P35465 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:12912914 | |
| P35465 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:15187108 | |
| Q08E52 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:10508610 | |
| Q08E52 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:11689432 | |
| Q08E52 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:12912914 | |
| Q08E52 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:14580336 | |
| Q08E52 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:15187108 | |
| Q13153 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:10508610 | |
| Q13153 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:11689432 | |
| Q13153 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:12912914 | |
| Q13153 | Serine_threonine-protein kinase PAK 1 | ISS | PubMed:15187108 | |
| PTHR48015:SF22 | A0A3Q1M0G8 | non-specific serine_threonine protein kinase | ISS | PubMed:15187108 |
| A0A3Q1M0G8 | non-specific serine_threonine protein kinase | ISS | PubMed:8626411 | |
| A0A8I3QD39 | non-specific serine_threonine protein kinase | ISS | PubMed:15187108 | |
| A0A8I3QD39 | non-specific serine_threonine protein kinase | ISS | PubMed:8626411 | |
| A0A8J0QMG0 | non-specific serine_threonine protein kinase | ISS | PubMed:10644687 | |
| A0A8J0QMG0 | non-specific serine_threonine protein kinase | ISS | PubMed:15187108 | |
| E1BS97 | non-specific serine_threonine protein kinase | ISS | PubMed:10644687 | |
| E1BS97 | non-specific serine_threonine protein kinase | ISS | PubMed:15187108 | |
| E1BS97 | non-specific serine_threonine protein kinase | ISS | PubMed:8626411 | |
| F7CU42 | Protein kinase domain-containing protein | ISS | PubMed:15187108 | |
| F7CU42 | Protein kinase domain-containing protein | ISS | PubMed:8626411 | |
| F7GWI2 | non-specific serine_threonine protein kinase | ISS | PubMed:15187108 | |
| F7GWI2 | non-specific serine_threonine protein kinase | ISS | PubMed:8626411 | |
| H2QP14 | non-specific serine_threonine protein kinase | ISS | PubMed:15187108 | |
| H2QP14 | non-specific serine_threonine protein kinase | ISS | PubMed:8626411 | |
| Q13177 | Serine_threonine-protein kinase PAK 2 | ISS | PubMed:15187108 | |
| Q13177 | Serine_threonine-protein kinase PAK 2 | ISS | PubMed:8626411 | |
| Q64303 | Serine_threonine-protein kinase PAK 2 | ISS | PubMed:15187108 | |
| Q64303 | Serine_threonine-protein kinase PAK 2 | ISS | PubMed:8626411 | |
| Q8CIN4 | Serine_threonine-protein kinase PAK 2 | ISS | PubMed:15187108 | |
| Q8CIN4 | Serine_threonine-protein kinase PAK 2 | ISS | PubMed:8626411 | |
| PTHR48015:SF27 | A0A2J8MSR9 | non-specific serine_threonine protein kinase | ISS | |
| A0A8I3PJQ0 | P21 (RAC1) activated kinase 5 | ISS | ||
| D4A280 | Serine_threonine-protein kinase PAK 5 | ISS | ||
| F1MY55 | non-specific serine_threonine protein kinase | ISS | ||
| F7FKL1 | non-specific serine_threonine protein kinase | ISS | ||
| Q8C015 | Serine_threonine-protein kinase PAK 5 | ISS | ||
| Q9P286 | Serine_threonine-protein kinase PAK 5 | ISS | ||
| PTHR48015:SF30 | A0A3Q1LNA9 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:11259591 |
| A0A3Q1LNA9 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:15187108 | |
| A0A3Q1LNA9 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:7559398 | |
| A0A3Q1LNA9 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:7559638 | |
| A0A5F8G6K2 | non-specific serine_threonine protein kinase | ISS | PubMed:11259591 | |
| A0A5F8G6K2 | non-specific serine_threonine protein kinase | ISS | PubMed:15187108 | |
| A0A5F8G6K2 | non-specific serine_threonine protein kinase | ISS | PubMed:7559398 | |
| A0A5F8G6K2 | non-specific serine_threonine protein kinase | ISS | PubMed:7559638 | |
| A0A6I8P0H1 | non-specific serine_threonine protein kinase | ISS | PubMed:11259591 | |
| A0A6I8P0H1 | non-specific serine_threonine protein kinase | ISS | PubMed:15187108 | |
| A0A6I8P0H1 | non-specific serine_threonine protein kinase | ISS | PubMed:7559398 | |
| A0A6I8P0H1 | non-specific serine_threonine protein kinase | ISS | PubMed:7559638 | |
| A0A8V0YYX2 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:11259591 | |
| A0A8V0YYX2 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:15187108 | |
| A0A8V0YYX2 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:7559398 | |
| A0A8V0YYX2 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:7559638 | |
| O75914 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:11259591 | |
| O75914 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:15187108 | |
| O75914 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:7559638 | |
| Q61036 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:15187108 | |
| Q61036 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:7559638 | |
| Q62829 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:15187108 | |
| Q62829 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:7559638 | |
| Q7YQL4 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:11259591 | |
| Q7YQL4 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:15187108 | |
| Q7YQL4 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:7559398 | |
| Q7YQL4 | Serine_threonine-protein kinase PAK 3 | ISS | PubMed:7559638 | |
| PTHR48015:SF35 | Q17850 | Serine_threonine-protein kinase pak-1 | ISS | |
| PTHR48015:SF4 | Q9VXE5 | Serine_threonine-protein kinase PAK mbt | ISS |
