Name: | RFC |
Definition: | Loads PCNA onto DNA, DNA-dependent ATPase (stimulated by PCNA), binds to primer terminus (3'-OH), binding requires ATP. Involved in polymerase switching: it disrupts the contacts between RPA and pol alpha/primase. This allows pol delta to couple to PCNA. |
Category ID: | P00529 |
Synonyms: | |
Upstream: | |
Downstream: | |
Number Families/Subfamilies: | 6 |
Number of Associated Sequences: | 16 |
GO Molecular Function: |
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GO Biological Process: |
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GO Cellular Component: |
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PANTHER protein class: |
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References: | http://oregonstate.edu/instruction/bb492/lectures/DNAIII.html |
Sequence Association
Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
PTHR11118:SF1 | Q8TU09 | tRNA-splicing ligase RtcB | ISS | |
PTHR11669:SF1 | P40938 | Replication factor C subunit 3 | RCA | |
Q5M830 | Replication factor C subunit 3 | RCA | ||
Q8R323 | Replication factor C subunit 3 | RCA | ||
PTHR11669:SF20 | B4F778 | Replication factor C subunit 4 | RCA | |
P35249 | Replication factor C subunit 4 | RCA | ||
Q99J62 | Replication factor C subunit 4 | RCA | ||
PTHR11669:SF5 | P35250 | Replication factor C subunit 2 | RCA | |
Q641W4 | Replication factor C subunit 2 | RCA | ||
Q9WUK4 | Replication factor C subunit 2 | RCA | ||
PTHR11669:SF9 | B5DF29 | Replication factor C subunit 5 | RCA | |
P40937 | Replication factor C subunit 5 | RCA | ||
Q9D0F6 | Replication factor C subunit 5 | RCA | ||
PTHR23389:SF6 | D3ZFT1 | Replication factor C subunit 1 | RCA | |
P35251 | Replication factor C subunit 1 | RCA | ||
P35601 | Replication factor C subunit 1 | RCA |